HIV Infection
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CLINICAL_TRIALS trial_result · 2008-08-21Clinical Trial Update: A Study of Male Rectal Samples in Preparation for Future Rectal Microbicide Trials
A completed clinical trial update studying male rectal samples in preparation for future rectal microbicide trials. It is sponsored by the N…
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FDA approval · 2008-08-15FDA Approved: REYATAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
FDA approved a supplemental application for Reyataz (atazanavir) submitted by E.R. Squibb & Sons, L.L.C., resulting in changes approved to t…
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CLINICAL_TRIALS trial_result · 2008-08-14Clinical Trial Update: The Safety and Effectiveness of Didanosine Plus Stavudine Plus Nevirapine Combined With MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors [Phase 2]
Phase 2 trial evaluating the safety and effectiveness of a four-drug regimen (didanosine, stavudine, nevirapine, and MKC-442) in HIV-infecte…
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CLINICAL_TRIALS trial_result · 2008-08-14Clinical Trial Update: The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors [Phase 2]
Phase 2 trial evaluating a four-drug regimen (didanosine, stavudine, delavirdine, MKC-442) in HIV infection patients who have not responded …
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CLINICAL_TRIALS research · 2008-08-13Clinical Trial Update: Computer-Assisted HIV Prevention for Young Drug Users [NA]
This entry outlines a clinical trial on computer-assisted HIV prevention targeting young drug users, with the current status listed as unkno…
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infection [Phase 4]
This Phase 4 trial assessed the immunogenicity of the 7-valent pneumococcal conjugate vaccine in the lung fluid of adults with and without H…
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin [Phase 1]
A Phase 1 pilot study evaluating a rapid methodology to assess bactericidal activity, tolerability, and pharmacokinetics of isoniazid and le…
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: Safety and Effectiveness of Immunotherapy With Autologous HIV-Specific CD8 Cells in HIV Infected Adults [Phase 1]
A Phase 1 study evaluated the safety and potential effectiveness of autologous HIV-specific CD8+ T cells in adults with HIV. The trial is co…
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: HIV and Genital Herpes Among High-Risk Men Who Have Sex With Men (MSM) in Lima, Peru
Completed clinical trial in Lima, Peru studying HIV infection and genital herpes among high-risk men who have sex with men, sponsored by NIA…
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CLINICAL_TRIALS research · 2008-08-07Clinical Trial Update: Immediate Versus Deferred Antiretroviral Therapy for HIV-Associated Tuberculous Meningitis [NA]
This entry discusses a clinical trial comparing immediate versus deferred initiation of antiretroviral therapy in HIV-infected patients with…
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CLINICAL_TRIALS trial_result · 2008-08-07Clinical Trial Update: Use of a Test That Evaluates How the Body Handles Insulin and Glucose
The clinical trial update reports that a study evaluating a test to assess how the body handles insulin and glucose in individuals with HIV …
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CLINICAL_TRIALS trial_result · 2008-08-07Clinical Trial Update: Hormonal Birth Control and the Risk of Acquiring HIV [NA]
This clinical trial update notes a completed study examining whether hormonal birth control influences the risk of acquiring HIV.
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CLINICAL_TRIALS trial_result · 2008-08-06Clinical Trial Update: A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4-Immunoglobulin G (rCD4-IgG) Administered by Intravenous Bolus Injection in Combination With Oral Zidovudine in Patients With AIDS and AIDS-Related Complex [Phase 1]
Phase I study evaluating the safety and pharmacokinetics of intravenous recombinant human CD4-immunoglobulin G (rCD4-IgG) in combination wit…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine in HIV Positive, Asymptomatic and Symptomatic Individuals [Phase 1]
A Phase 1 clinical trial assessed the safety and potential efficacy of combining polyethylene glycol–conjugated interleukin-2 (PEG IL-2) wit…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS [Phase 1]
A Phase 1 trial evaluating the safety and preliminary effectiveness of combining clarithromycin with zidovudine or didanosine for Mycobacter…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection
This clinical trial compares HIV-infected patients with and without AIDS-related opportunistic infections, examining outcomes related to cyt…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: A Randomized Study of Activity, Safety, and Tolerance of Oral Ro 24-7429 (Tat Antagonist) in Patients With HIV Infection [Phase 1]
Phase 1 randomized study evaluating activity, safety, and tolerance of the oral Tat antagonist Ro 24-7429 in HIV infection.
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CLINICAL_TRIALS trial_result · 2008-08-01Clinical Trial Update: A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C Infection
This clinical trial update indicates a study evaluating anti-HIV drugs in HIV-positive patients with Hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2008-08-01Clinical Trial Update: Setting up a Blood Bank for Gene Therapy in HIV-Infected Infants
This update reports termination of a clinical trial (NCT00000917) sponsored by NIAID that aimed to set up a blood bank to support gene thera…
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CLINICAL_TRIALS withdrawal · 2008-08-01Clinical Trial Update: Withdrawal of Antifungal Treatment for Histoplasmosis in Patients After Improved Immune Response to Anti-HIV Drugs
This clinical trial update reports withdrawal of antifungal treatment for histoplasmosis in patients who showed improved immune response to …
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CLINICAL_TRIALS trial_result · 2008-07-31Clinical Trial Update: Daily Nevirapine to Prevent Mother to Infant Transmission of HIV [Phase 3]
Phase 3 trial evaluating daily nevirapine to prevent mother-to-child transmission of HIV has completed.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: Treatment of Hepatitis C in Hemophilic Patients With HIV [Phase 2]
A completed Phase 2 clinical trial evaluated treatment for Hepatitis C in patients with HIV infection and hemophilia.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive Patients
A completed clinical trial assessed the effects of stopping preventive therapy for Mycobacterium avium complex infection in HIV-positive pat…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection [Phase 1]
A Phase 1 clinical trial evaluates the safety and effectiveness of a regimen combining Interleukin-2 with Zidovudine and Thymosin in HIV-inf…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: An Open-Label, Staggered Rising Dose Cohort Study Assessing the Pharmacokinetics, Safety, and Tolerance of BI-RG-587 in Combination With Zidovudine in Patients With HIV Infection (CD4+ Cell Count < 400/mm3) [Phase 1]
This Phase 1 open-label study evaluated the pharmacokinetics, safety, and tolerability of BI-RG-587 in combination with zidovudine in HIV-in…