HIV Infection
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CLINICAL_TRIALS trial_result · 2011-03-01Clinical Trial Update: The Effects of Zidovudine on the Blood of HIV-Infected Patients [NA]
The document reports the completion of a clinical trial evaluating the effects of Zidovudine on blood parameters in HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2011-03-01Clinical Trial Update: Observational Study of the Therapeutic Study of Recombinant HIV-1 TAT
This document reports the completion of an observational trial evaluating the therapeutic use of recombinant HIV-1 Tat protein for HIV infec…
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CLINICAL_TRIALS trial_result · 2011-03-01Clinical Trial Update: CMV Retinitis Retreatment Trial [Phase 2]
A Phase 2 retreatment trial investigating cytomegalovirus retinitis in HIV-infected individuals has completed.
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FDA approval · 2011-02-25FDA Approved: VIRACEPT — Supplemental Application (AGOURON)
The FDA approved a supplemental application for Viracept (nelfinavir mesylate) submitted by Agouron, updating the approved labeling for the …
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FDA approval · 2011-02-25FDA Approved: VIRACEPT — Supplemental Application (AGOURON)
FDA approved a supplemental application for VIRACEPT (nelfinavir mesylate) from Agouron.
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Safety of Cotrimoxazole in HIV- and HAART-exposed Infants [Phase 4]
Phase 4 safety evaluation of cotrimoxazole (sulfamethoxazole-trimethoprim) in HIV- and HAART-exposed newborns has completed, noting safety e…
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS [Phase 2]
Phase II study assessing the safety and efficacy of clarithromycin for disseminated Mycobacterium avium complex infection in patients with A…
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Minocycline for HIV+ Cognitive Impairment in Uganda [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating minocycline for HIV-associated neurocognitive disorder was terminated; results were posted in 2011.
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FDA label_change · 2011-02-24FDA Approved: KALETRA — Supplemental Application (AbbVie Inc.)
FDA approved a supplemental application for KALETRA (lopinavir/ritonavir), updating its labeling.
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FDA approval · 2011-02-24FDA Approved: KALETRA — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for KALETRA (lopinavir/ritonavir) from AbbVie, updating the product labeling for HIV infection.
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FDA approval · 2011-02-24FDA Approved: ISENTRESS — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for Isentress (raltegravir) from Merck Sharp & Dohme LLC. The action approves changes to the labelin…
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: The Effects of Prednisone on HIV Levels and the Immune System [Phase 2]
A Phase 2 clinical trial sponsored by NIAID evaluated prednisone for its effects on HIV viral levels and immune system parameters. The study…
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: Efavirenz and Lamivudine/Zidovudine for Treatment-Naive HIV Infected People in Wenxi County, Shanxi Province, China [NA]
A completed clinical trial evaluating efavirenz in combination with lamivudine/zidovudine for treatment-naive HIV infection in Wenxi County,…
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis [Phase 4]
Phase 4 trial comparing cidofovir and ganciclovir for cytomegalovirus retinitis in HIV/AIDS patients has completed.
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CLINICAL_TRIALS trial_result · 2011-02-21Clinical Trial Update: Clinical Study of TUTI-16 in Asymptomatic HIV-1 Infected Subjects [Phase 1, Phase 2]
Phase 1/2 study of TUTI-16 in asymptomatic HIV-1 infected subjects completed; results were posted on 2011-02-21.
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CLINICAL_TRIALS trial_result · 2011-02-17Clinical Trial Update: Prevalence of HIV and Tuberculosis in Masiphumelele Township, Cape Town, South Africa
This clinical trial update reports on the prevalence of HIV infection and tuberculosis in Masiphumelele Township, Cape Town, with results po…
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CLINICAL_TRIALS trial_result · 2011-02-16Clinical Trial Update: Can Presumptive Anthelminthic Treatment Delay the Progression of HIV in ART-naïve Patients in Rural Africa? [NA]
A terminated clinical trial (NCT00817713) investigated whether presumptive anthelminthic treatment could delay HIV progression in ART-naïve …
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CLINICAL_TRIALS trial_result · 2011-02-15Clinical Trial Update: Safety of and Immune Response to a Pneumococcal Vaccine (PncCV) in HIV Infected and Uninfected Children [NA]
A clinical trial update reports on the safety and immune response to a pneumococcal vaccine (PncCV) in HIV-infected and uninfected children.
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CLINICAL_TRIALS trial_result · 2011-02-11Clinical Trial Update: Pharmacokinetics of Lamivudine at Two Different Doses [Phase 1, Phase 2]
The document reports pharmacokinetic findings for lamivudine at two different doses from a Phase 1/2 trial.
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CLINICAL_TRIALS trial_result · 2011-02-11Clinical Trial Update: Reactogenicity and Immunogenicity of Vaginal CNgp140 [Phase 1]
Phase 1 trial evaluating the reactogenicity and immunogenicity of vaginal CNgp140 in HIV infection and AIDS; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2011-02-10Clinical Trial Update: Pilot Study Evaluating Interruption of Enfuvirtide (Fuzeon, T20) in Patients With Enfuvirtide Resistance [Phase 4]
A Phase 4 pilot trial evaluates whether interrupting enfuvirtide (Fuzeon) is feasible in patients with enfuvirtide resistance; the study is …
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CLINICAL_TRIALS research · 2011-02-10Clinical Trial Update: Structured Treatment Interruption (STI) in Acute/Primary HIV [NA]
ClinicalTrials.gov entry describing a structured treatment interruption study in acute/primary HIV; current status is UNKNOWN.
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CLINICAL_TRIALS research · 2011-02-09Clinical Trial Update: Characteristics and Prevalence of Tuberculosis and HIV in Masiphumelele Township, Cape Town, South Africa
This completed clinical trial analyzes the characteristics and prevalence of HIV infection and tuberculosis in Masiphumelele Township, Cape …
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CLINICAL_TRIALS trial_result · 2011-02-09Clinical Trial Update: Acceptability Study of Vaginal Films for HIV Prevention
This clinical trial registry entry reports the completion of an acceptability study evaluating vaginal films for HIV prevention.
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CLINICAL_TRIALS trial_result · 2011-02-08Clinical Trial Update: Plasma and Intracellular Concentrations of Raltegravir and Etravirine Administered Once Daily [Phase 4]
Phase 4 pharmacokinetic study measuring plasma and intracellular concentrations of raltegravir and etravirine given once daily in HIV-1 infe…