HIV Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: BRAVO: Background Regimen of Raltegravir on Virologic Outcome
Clinical trial BRAVO studied a background regimen including raltegravir for HIV; the trial is completed and results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-06-16Clinical Trial Update: Evaluation of Two Anti-HIV Treatment Strategies in Resource-Limited South African Communities [NA]
Completed clinical trial in resource-limited South African communities comparing two anti-HIV treatment strategies; results were posted in 2…
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CLINICAL_TRIALS trial_result · 2011-06-16Clinical Trial Update: Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1-infected Mothers [Phase 1, Phase 2]
A Phase 1/2 study evaluating the safety and immunogenicity of a candidate HIV-1 vaccine administered to healthy infants born to HIV-1-infect…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: TMC125-C216: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options. [Phase 3]
Phase III study TMC125-C216 evaluates etravirine (TMC125) as part of an antiretroviral regimen including TMC114/ritonavir in HIV-1 infected …
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: TMC114-C213: A Phase II Randomized, Controlled, Partially Blinded Trial to Investigate Dose-response of TMC114/RTV in 3-class-experienced HIV-1 Infected Patients, Followed by an Open-label Period on the Recommended Dose of TMC114/RTV. [Phase 2]
This Phase II trial update reports the completion of a randomized, partially blinded dose-response study of darunavir/ritonavir in 3-class e…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: TB (Tuberculosis) Preventive Therapy for HIV Patients With Access to HAART (Highly Active Antiretroviral Therapy) [Phase 4]
Phase 4 study evaluating tuberculosis preventive therapy in people with HIV on HAART has completed.
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: Peginterferon Alpha-2a and Ribavirin to Treat Hepatitis C in HIV-infected Patients [Phase 2]
Phase 2 trial evaluating pegylated interferon alfa-2a plus ribavirin for treating Hepatitis C in HIV-infected patients completed, with resul…
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CLINICAL_TRIALS research · 2011-06-15Clinical Trial Update: A Trial to Compare Raltegravir Versus Nevirapine as Anchor Drug for HIV+ Chinese IDUs on Methadone Maintenance [NA]
A clinical trial comparing raltegravir versus nevirapine as anchor antiretroviral therapy for HIV-positive Chinese individuals who inject dr…
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CLINICAL_TRIALS trial_result · 2011-06-14Clinical Trial Update: Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy [Phase 3]
Phase 3 trial of NGX-4010 (capsaicin 8% patch) for painful HIV-associated neuropathy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2011-06-10Clinical Trial Update: A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers [Phase 2]
Phase IIa trial evaluating the safety and immunogenicity of a DNA HIV-1 vaccine followed by an MVA HIV-1 vaccine in HIV-uninfected volunteer…
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FDA approval · 2011-06-10FDA Approved: ISENTRESS — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for Isentress (raltegravir) by Merck Sharp & Dohme LLC.
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CLINICAL_TRIALS trial_result · 2011-06-10Clinical Trial Update: TMC114-C209: A Study of Safety of TMC114 With Low Dose Ritonavir (RTV) and Other Antiretrovirals in Experienced HIV-1 Infected Patients With Limited or no Treatment Options [Phase 3]
Phase 3 study assessing safety of TMC114 (darunavir) boosted with low-dose ritonavir in experienced HIV-1 infected patients with limited or …
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CLINICAL_TRIALS trial_result · 2011-06-10Clinical Trial Update: Prevalence and Determinants of Chronic Obstructive Pulmonary Disease (COPD) in HIV+ Patients
This completed trial reports on the prevalence and determinants of COPD in HIV-positive patients.
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CLINICAL_TRIALS trial_result · 2011-06-10Clinical Trial Update: A Study to Assess the Effectiveness of PROCRIT (Epoetin Alfa) Dosing Every 2 Weeks Versus Once a Week in Anemic HIV-infected Patients [Phase 2]
A Phase 2 trial comparing PROCRIT (epoetin alfa) dosing every two weeks versus once weekly in anemic HIV-infected patients; the study was te…
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 and Two Antifungal Agents (Fluconazole and Voriconazole), All at Steady-state in Healthy Subjects. [Phase 1]
A Phase I, open-label trial evaluated the pharmacokinetic interaction between TMC125 (etravirine) and the antifungal agents fluconazole and …
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: TMC114-TiDP29-C169: Bioavailability and Pharmacokinetics Trial Comparing Darunavir Pediatric Suspension Formulation to Current Darunavir Tablet [Phase 1]
Phase 1 bioavailability and pharmacokinetics study comparing the pediatric suspension formulation of darunavir to the current tablet was com…
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: TMC278-TiDP38-C145: A Bioavailability Study in Healthy Adult Volunteers to Evaluate 3 Pediatric Formulations of TMC278 (a Solution, a Suspension, and Granules) Compared to an Adult Tablet Formulation [Phase 1]
Phase 1 bioavailability study in healthy adult volunteers evaluating three pediatric formulations of TMC278 (rilpivirine) against the adult …
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: Bavituximab Repeat-Dose Trial in Patients Co-Infected With Chronic Hepatitis C Virus and Human Immunodeficiency Virus [Phase 1]
Phase 1 repeat-dose trial of bavituximab in patients co-infected with hepatitis C and HIV has completed.
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: TMC125-TiDP2-C197: A Phase I Trial to Investigate the Pharmacokinetic Interaction Between Lopinavir/Ritonavir and TMC125 Both at Steady-state in Healthy Volunteers. [Phase 1]
This completed Phase I study evaluated the pharmacokinetic interaction between lopinavir/ritonavir and TMC125 (rilpivirine) in healthy volun…
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: TMC125-TiDP2-C188: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Effect of Multiple-dose TMC125 on Buprenorphine and Norbuprenorphine Administered in HIV-negative Patients on Stable Buprenorphine/Naloxone Maintenance Therapy. [Phase 1]
Phase I open-label trial to assess pharmacokinetic interaction between TMC125 (etravirine) and buprenorphine/naloxone in HIV-negative patien…
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CLINICAL_TRIALS trial_result · 2011-06-08Clinical Trial Update: Safety and Efficacy of T Cell Genetic Immunotherapy for HIV [Phase 2]
A Phase 2 trial update from VIRxSYS Corporation evaluating the safety and efficacy of a T cell genetic immunotherapy for HIV.
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CLINICAL_TRIALS trial_result · 2011-06-08Clinical Trial Update: Development of a New HIV Vaccine [Phase 1]
Completion of a Phase 1 clinical trial evaluating a new HIV vaccine sponsored by NIAID.
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CLINICAL_TRIALS research · 2011-06-08Clinical Trial Update: A Rollover Study for Subjects Who Completed Participation in the VRX496-USA-05-002 Trial [Phase 2]
This document describes a rollover study for subjects who completed participation in the VRX496-USA-05-002 Phase 2 trial for HIV infection.
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CLINICAL_TRIALS research · 2011-06-08Clinical Trial Update: Prospective Epidemiological Study Of The Prevalence Of HLA-B*5701 In HIV-1 Infected Patients
This completed prospective study assessed how common the HLA-B*57:01 allele is among HIV-1 infected individuals.
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CLINICAL_TRIALS trial_result · 2011-05-25Clinical Trial Update: A Randomised, Open-label Trial to Assess the Safety and Efficacy of Switching to Tenofovir-emtricitabine or Abacavir-lamivudine: The STEAL Study [Phase 4]
The STEAL trial evaluated safety and efficacy after switching HIV patients to either tenofovir-emtricitabine or abacavir-lamivudine in an op…