HIV Infection
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CLINICAL_TRIALS trial_result · 2013-05-31Clinical Trial Update: Study of PRO 140 by Subcutaneous Administration in Adult Subjects With HIV -1 Infection [Phase 2]
This is a Phase 2 study update for PRO 140 (leronlimab) given subcutaneously to adults with HIV-1 infection. The trial has completed and res…
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CLINICAL_TRIALS trial_result · 2013-05-31Clinical Trial Update: PRO 140 by IV Administration in Adults With HIV-1 Infection [Phase 2]
A Phase 2 clinical trial evaluating intravenous PRO 140 (leronlimab) in adults with HIV-1 infection has completed and posted results.
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Feasibility of a Hepatitis C Virus (HCV) Decision-Making Intervention Among HIV-infected Adults [NA]
A completed clinical trial evaluating the feasibility of a Hepatitis C decision-making intervention in HIV-infected adults.
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FDA approval · 2013-05-28FDA Approved: VIRACEPT — Supplemental Application (AGOURON)
FDA approved a supplemental application for Viracept (nelfinavir mesylate) filed by Agouron.
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FDA approval · 2013-05-28FDA Approved: VIRACEPT — Supplemental Application (AGOURON)
The FDA approved a supplemental application for Viracept (nelfinavir mesylate) submitted by Agouron.
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FDA approval · 2013-05-28FDA Approved: ISENTRESS — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for ISENTRESS (raltegravir) from Merck Sharp & Dohme LLC, indicating an update to the drug's lab…
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CLINICAL_TRIALS trial_result · 2013-05-27Clinical Trial Update: The Effect of Raltegravir on HIV Decay During Primary and Chronic Infection [NA]
A clinical trial assessed the effect of raltegravir on HIV decay during primary and chronic HIV infection; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder [Phase 2]
Phase 2 clinical trial evaluating the STIRR intervention for people with co-occurring mental illness and substance use disorders; results we…
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Impact of a Computer-Assisted SBIRT Program in an HIV Care Setting
This completed clinical trial evaluates the impact of a computer-assisted SBIRT program implemented in HIV care settings on substance use ou…
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: Observational Study of Blood Treated With Cytolin
A completed observational study evaluating Cytolin (leronlimab) treatment in HIV infection.
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CLINICAL_TRIALS trial_result · 2013-05-20Clinical Trial Update: A School-Based HIV/STD Prevention Program to Reduce Risky Sexual Behaviors Among Adolescents in Liberia [NA]
This entry notes the completion of a school-based HIV/STD prevention program trial aimed at reducing risky sexual behaviors among adolescent…
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CLINICAL_TRIALS trial_result · 2013-05-20Clinical Trial Update: Prevention of Milk-Borne Transmission of HIV-1C in Botswana [NA]
A completed clinical trial evaluating strategies to prevent mother-to-child transmission of HIV-1 subtype C via breast milk in Botswana.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Evaluating the Effectiveness of Pentoxifylline at Improving Blood Vessel Function in HIV-infected People Not Receiving Antiretroviral Medications [Phase 2]
Phase 2 trial results assess pentoxifylline's effectiveness at improving blood vessel function in HIV-infected individuals not on antiretrov…
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Pilot Study to Assess Gut Mucosal B Cells in Individuals With HCV and HIV
This pilot trial evaluating gut mucosal B cells in individuals with HIV infection and hepatitis C has been terminated.
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CLINICAL_TRIALS trial_result · 2013-05-16Clinical Trial Update: Entecavir Intensification for Persistent HBV Viremia in HIV-HBV Infection [Phase 4]
Phase 4 clinical trial evaluating intensification of entecavir for persistent HBV viremia in people with HIV-HBV infection; results were pos…
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CLINICAL_TRIALS trial_result · 2013-05-16Clinical Trial Update: A Trial Examining the Efficacy of Escitalopram Oxalate Upon Depressive Symptoms and Fatigue in HIV Seropositive Women [Phase 4]
A Phase 4 trial evaluating escitalopram oxalate for depressive symptoms and fatigue in HIV seropositive women was terminated; results were p…
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CLINICAL_TRIALS trial_result · 2013-05-15Clinical Trial Update: A Safety and Tolerability Study of Nitazoxanide in HIV-HCV Treatment Failures [Phase 1, Phase 2]
A safety and tolerability study of nitazoxanide in individuals with HIV and hepatitis C who failed prior treatment (Phase 1/2; completed wit…
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: A Randomized, Prospective Study of the Efficacy, Safety and Tolerability of Two Doses of GW433908Ritonavir Given With Abacavir/Lamivudine Fixed Dose Combination [Phase 4]
Completed Phase 4 randomized trial evaluating two doses of GW433908 boosted with ritonavir in combination with abacavir/lamivudine, assessin…
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: HIV Diagnosis in Hospitalized Malawian Infants [NA]
This clinical trial, sponsored by the University of North Carolina, Chapel Hill, evaluated HIV diagnosis in hospitalized infants in Malawi. …
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CLINICAL_TRIALS trial_result · 2013-05-13Clinical Trial Update: The Efavirenz (EFV) Central Nervous System Exposure Sub-study of Encore1 [Phase 3]
The update reports results from the Efavirenz CNS exposure sub-study of the Encore1 Phase 3 trial in HIV infection.
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CLINICAL_TRIALS trial_result · 2013-05-13Clinical Trial Update: The Intensive Pharmacokinetics Sub-study of Encore1 (ENCORE1-PK) [Phase 3]
The document reports the completion of the intensive pharmacokinetics sub-study ENCORE1-PK connected to the ENCORE1 Phase 3 HIV trial.
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CLINICAL_TRIALS trial_result · 2013-05-13Clinical Trial Update: Maintenance Boosted Lopinavir Monotherapy Following Salvage Protease-inhibitor (PI) Based Regimen in HIV With Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI) Based Regimen Failure [Phase 4]
Phase 4 clinical trial evaluating maintenance boosted lopinavir monotherapy after salvage protease inhibitor–based therapy in HIV patients w…
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FDA approval · 2013-05-10FDA Approved: COMPLERA — Supplemental Application (Gilead Sciences, Inc.)
FDA approved a supplemental application for COMPLERA to update its labeling.
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CLINICAL_TRIALS trial_result · 2013-05-07Clinical Trial Update: Evaluation of Cardiovascular Effects of Smoking Cessation in HIV Patients
A completed clinical trial evaluated how smoking cessation impacts cardiovascular health in people with HIV.
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CLINICAL_TRIALS research · 2013-05-06Clinical Trial Update: Non-interventional Study on Use of Darunavir With Ritonavir in Clinical Practice
An observational non-interventional study examining how darunavir boosted with ritonavir is used in routine HIV care, sponsored by Janssen-C…