HIV Infection
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CLINICAL_TRIALS research · 2014-07-03Clinical Trial Update: Phase II Randomised Controlled Trial of Memory Work Therapy at PASADA, Tanzania [NA]
A Phase II randomized controlled trial evaluating memory work therapy for people living with HIV at PASADA in Dar es Salaam, Tanzania; curre…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: A Trial Comparing GSK1349572 50mg Plus Abacavir/Lamivudine Once Daily to Atripla (Also Called The SINGLE Trial) [Phase 3]
Phase 3 SINGLE trial comparing dolutegravir/abacavir/lamivudine once daily to Atripla (efavirenz/emtricitabine/tenofovir) in HIV-1 infection…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: Biobehavioral Interventions for HIV-negative, Stimulant Using Men Who Have Sex With Men [Phase 2]
A Phase 2 clinical trial of biobehavioral interventions for HIV-negative, stimulant-using men who have sex with men has completed enrollment…
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CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: Comparing Blood Vessel Endothelial Function in HIV-Infected People and Matched HIV-Uninfected People
The study evaluated differences in blood vessel endothelial function between HIV-infected participants and matched HIV-uninfected controls; …
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Evaluation of a Lopinavir/Ritonavir Monotherapy vs a Triple Therapy as Maintenance Regimens in HIV-1 Infected Patients [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating lopinavir/ritonavir monotherapy versus a triple-therapy maintenance regimen in HIV-1 infected patients has …
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Development and Evaluation of an HIV, STD, and Pregnancy Prevention Program for Middle School Students [NA]
A clinical trial evaluating an HIV, sexually transmitted infection, and pregnancy prevention program for middle school students has complete…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options. [Phase 3]
A Phase III study (TMC125-C206) evaluated etravirine (TMC125) as part of an antiretroviral regimen with darunavir/ritonavir and an investiga…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: An Open Label Trial of TMC114/RTV in HIV-1 Infected, Treatment-experienced Subjects. [Phase 2]
This update reports the completion of a Phase 2 open-label trial of TMC114/RTV (darunavir/ritonavir) in HIV-1 infected, treatment-experience…
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: The Rilpivirine Cerebrospinal-fluid (CSF) Study [Phase 1]
Phase 1 study assessing rilpivirine concentrations in cerebrospinal fluid in HIV-infected participants. The study is completed with results …
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: A Feasibility Study to Assess Tenofovir and Maraviroc Protection Against HIV-1 in Cervical and Vaginal Explants [Phase 1]
A Phase 1 feasibility study evaluated whether tenofovir and maraviroc can protect against HIV-1 infection in cervical and vaginal explants f…
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FDA approval · 2014-06-18FDA Approved: TRUVADA — Supplemental Application (Gilead Sciences, Inc)
FDA approved a supplemental application for Truvada (emtricitabine/tenofovir disoproxil fumarate) filed by Gilead Sciences, Inc.
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CLINICAL_TRIALS trial_result · 2014-06-16Clinical Trial Update: Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C Infections [Phase 4]
A Phase 4 trial evaluating pioglitazone for fatty liver disease in patients with HIV and hepatitis C was terminated, with results posted in …
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CLINICAL_TRIALS trial_result · 2014-06-16Clinical Trial Update: Effects of Probiotics on Microbial Translocation and Immune Activation Markers in HIV-positive Patients on Combined Antiretroviral Therapy [NA]
The study evaluates whether probiotic supplementation affects microbial translocation and immune activation markers in HIV-infected individu…
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CLINICAL_TRIALS trial_result · 2014-06-13Clinical Trial Update: Web-Based Middle School HIV Prevention Curricula: Aspiring for Reach and Impact [NA]
A web-based HIV prevention curriculum trial for middle school students has completed, aiming to assess reach and impact.
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CLINICAL_TRIALS research · 2014-06-13Clinical Trial Update: Zinc Supplementation Effect on Immune Recovery in HIV Patients [NA]
This entry documents a clinical trial evaluating zinc supplementation for immune recovery in HIV/AIDS patients. The current status is unknow…
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CLINICAL_TRIALS trial_result · 2014-06-12Clinical Trial Update: Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS [Phase 4]
A Phase 4 trial evaluated armodafinil for treating fatigue in adults with HIV infection; results were posted after the study was completed.
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: Men of African American Legacy Empowering Self [Phase 2]
Clinical trial update noting the completion of a Phase 2 study addressing HIV under the Men of African American Legacy Empowering Self progr…
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CLINICAL_TRIALS trial_result · 2014-06-10Clinical Trial Update: Outcomes for Antiretroviral Therapy Patients Receiving Palliative Care [Phase 2, Phase 3]
A completed Phase 2 and Phase 3 clinical trial from King's College London evaluating outcomes for HIV patients on antiretroviral therapy rec…
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: Effectiveness of Modafinil for Treating Fatigue in Adults With HIV/AIDS [Phase 4]
Phase 4 study evaluating the effectiveness of modafinil for reducing fatigue in adults with HIV infection has completed; results were posted…
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022 [Phase 2]
A Phase 2 long-term safety study of lersivirine in HIV infection patients who completed prior lersivirine trials has been terminated.
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CLINICAL_TRIALS trial_result · 2014-06-06Clinical Trial Update: Vitamin D Supplementation and CD4 Count in HIV-Infected Children [Phase 2]
This document notes the completion of a Phase 2 trial assessing whether vitamin D supplementation affects CD4 counts in HIV-infected childre…
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CLINICAL_TRIALS trial_result · 2014-06-06Clinical Trial Update: Effectiveness of Opiate Replacement Therapy Administered Prior to Release From a Correctional Facility - 1 [NA]
A completed trial analyzes the effectiveness of opiate replacement therapy administered before release from a correctional facility. Results…
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FDA approval · 2014-06-05FDA Approved: COMPLERA — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for COMPLERA (emtricitabine, rilpivirine hydrochloride, and tenofovir disoproxil fumarate) from …
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CLINICAL_TRIALS trial_result · 2014-06-05Clinical Trial Update: CID 0911 - Adaptation of A Depression Treatment Intervention for HIV Patients in Cameroon
CID 0911 is a trial adapting a depression treatment intervention for people with HIV in Cameroon. The study, sponsored by the University of …
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CLINICAL_TRIALS trial_result · 2014-06-04Clinical Trial Update: Immune Response After Booster Vaccination in HIV - Infected Patients Who Received Rabies Primary Vaccination [NA]
This clinical trial update reports the immune response to a rabies booster in HIV-infected patients who had received a rabies primary vaccin…