HIV Infection
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Sign up freeTop drugs studied for this disease
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FDA approval · 2014-10-10FDA Approved: ISENTRESS — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for Isentress (raltegravir) from Merck Sharp & Dohme LLC.
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CLINICAL_TRIALS trial_result · 2014-10-10Clinical Trial Update: Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy [Phase 3]
Phase 3 trial evaluating lipid changes and safety of raltegravir in HIV-infected patients with hyperlipidemia on current standard therapy. T…
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CLINICAL_TRIALS trial_result · 2014-10-10Clinical Trial Update: Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission
This clinical trial update covers prenatal and postnatal interventions aimed at preventing mother-to-child transmission of HIV; the study is…
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: Quality of Life of HIV-infected Participants Switched to Raltegravir Versus Other Antiretroviral Regimens (MK-0518-266)
The terminated MK-0518-266 trial assessed quality of life in HIV-infected participants who switched to raltegravir versus other antiretrovir…
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: HIV Viral Load Monitoring in Resource-Poor Settings [NA]
A completed clinical trial assessing HIV viral load monitoring in resource-poor settings.
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM) [Phase 1, Phase 2]
This update reports on a Phase 1/2 clinical trial aimed at reducing HIV risk among episodic substance-using men who have sex with men (SUMSM…
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Utility of Urinary beta2 Microglobulin as an Early Marker of Renal Dysfunction in Vietnamese HIV-Infected Patients
Clinical trial update evaluating urinary beta-2 microglobulin as an early marker of renal dysfunction in Vietnamese patients with HIV infect…
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CLINICAL_TRIALS trial_result · 2014-10-02Clinical Trial Update: Open Label Study to Evaluate Chronic Hepatitis C Treatment in Latino Subjects With and Without HIV Co-infection
Open-label study assessing chronic hepatitis C treatment in Latino patients with and without HIV co-infection; study terminated with results…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected Patients [Phase 2]
A Phase 2 trial evaluating peginterferon alfa-2b plus ribavirin for treating hepatitis C in HIV-infected patients is completed, with results…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients. [Phase 1, Phase 2]
This clinical trial update reports Part A on drug interaction between sofosbuvir and antiretroviral therapy in HIV/HCV co-infected patients,…
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Choices-Teen: A Bundled Risk Reduction Intervention for Juvenile Justice Females [NA]
This is a completed trial update for Choices-Teen, a bundled risk-reduction intervention aimed at juvenile justice females to address alcoho…
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Enhanced HIV Prevention in Couples: Feasibility Study #3
Completion report for Feasibility Study #3 evaluating enhanced HIV prevention in couples.
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: A Two Way Cross Over Pharmacokinetic Interaction Study Between Raltegravir and Amlodipine in Healthy Volunteers [Phase 1]
Phase 1 cross-over pharmacokinetic study in healthy volunteers to assess the interaction between raltegravir and amlodipine; results were po…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: Effects of Tipranavir/Ritonavir on the Pharmacokinetic Characteristics of Triple Drug Nucleoside and Non-nucleoside Reverse Transcriptase Inhibitor Therapy in HIV-1-infected Subjects [Phase 1, Phase 2]
Phase 1/2 study evaluating the pharmacokinetic impact of boosted tipranavir/ritonavir on a triple-drug nucleoside and non-nucleoside reverse…
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CLINICAL_TRIALS research · 2014-09-29Clinical Trial Update: Qualitative Assessment of Implementing Routine Rapid HIV Testing
This update reports the results of a qualitative assessment exploring how routine rapid HIV testing can be implemented in clinical settings.…
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: Effects of CYP2B6 Genetic Polymorphisms on Efavirenz Pharmacokinetics [NA]
This clinical trial update reports on how CYP2B6 genetic polymorphisms affect the pharmacokinetics of efavirenz in HIV patients.
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: HIV-1 Specific Immune Responses in Thai Individuals With HIV Dementia
This document announces the completion of a clinical trial investigating HIV-1 specific immune responses in Thai individuals with HIV dement…
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: Epidermal Nerve Fiber Density, Fat and Mitochondrial Parameters in Thai HIV+ Patients on d4T and HIV- Patients
This clinical trial compares epidermal nerve fiber density, fat, and mitochondrial parameters between Thai HIV-positive patients on stavudin…
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CLINICAL_TRIALS research · 2014-09-26Clinical Trial Update: Establishing Normal Values for Neuropsychological Testing in HIV-negative Thais
The trial completed establishing normal neuropsychological test values for HIV-negative Thai individuals.
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: NRTI-Sparing Pilot Study [Phase 4]
Phase 4 pilot trial evaluating NRTI-sparing regimens in people with HIV; the study focusing on mitochondrial toxicity has completed.
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIV
This completed clinical trial studied whether peripheral HIV DNA in monocytes relates to cognitive outcomes in people with HIV.
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CLINICAL_TRIALS trial_result · 2014-09-25Clinical Trial Update: Tipranavir Dose-response Study Using a Prototype Self-emulsifying Drug Delivery System (SEDDS) Formulation in Treatment-naive HIV-1 Infected Patients Report on the Post-study Option, a Treatment of Triple Therapy With Delavirdine, ZDV and 3TC Without Tipranavir [Phase 2]
A Phase 2 dose-response trial of tipranavir in a self-emulsifying drug delivery system in treatment-naive HIV-1 infected patients, including…
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CLINICAL_TRIALS research · 2014-09-25Clinical Trial Update: HIV Liver Regeneration Project for HIV Patients With Cirrhosis by Autologous Bone Marrow Transplantation [NA]
Ongoing clinical trial investigating autologous bone marrow transplantation for HIV patients with cirrhosis; current status is unknown.
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FDA approval · 2014-09-24FDA Approved: TYBOST — Original Application (Gilead Sciences, Inc.)
Tybost (cobicistat) received FDA approval as an original application from Gilead Sciences; cobicistat is a pharmacokinetic booster used in H…
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Community-based Delivery of Integrated Family Planning/HIV Testing and Counseling Services in Uganda [NA]
A completed community-based trial in Uganda evaluated integrating family planning services with HIV testing and counseling.