HIV Infection
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Heart Function in HIV-Negative Children Exposed to HIV and HAART
This completed clinical trial evaluated heart function in HIV-exposed uninfected children who were exposed to HIV and HAART; results were po…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Study of Anti-HIV Cellular Therapy Based on Dendritic Cells Pulsed With Chemically Inactivated Virus [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a dendritic cell–based HIV vaccine pulsed with chemically inactivated virus has completed.
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Thol'Impilo: Bringing People Into Care [NA]
This document provides an update on the Thol'Impilo trial aimed at bringing people into HIV care. The study status is listed as completed.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa [NA]
A completed clinical trial evaluating early versus delayed antiretroviral therapy in patients with cryptococcal meningitis and HIV infection…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: H1N1 Influenza Vaccine Immunogenicity in HIV-1 Infected Patients [Phase 4]
Phase 4 clinical trial evaluating the immunogenicity of the H1N1 influenza vaccine in HIV-1 infected patients; results were posted in 2016.
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CLINICAL_TRIALS research · 2016-07-12Clinical Trial Update: Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa [Phase 2, Phase 3]
This is an update on a Phase 2/3 clinical trial evaluating high-dose fluconazole in combination with flucytosine as induction therapy for cr…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Immuno-stimulation With Maraviroc Combined to Antiretroviral Therapy in Advanced Late Diagnosed HIV-1 Infected Patients [Phase 3]
Phase 3 trial assessed immunostimulation with maraviroc added to antiretroviral therapy in advanced HIV infection (AIDS) and has completed.
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CLINICAL_TRIALS research · 2016-07-12Clinical Trial Update: Disability and HIV: Vulnerability of People With Disabilities to HIV Infection in Sub-Saharan Africa
A completed clinical trial update exploring how disability intersects with HIV infection risk and reproductive health in Sub-Saharan Africa.
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Values of the Immune Activation Markers CD38 and HLA-DR and the Ratio CD4/CD8 According to the Delay of Combined AntiRetroviral Therapy (c-ART) Initiation in Primary HIV-infected Patients (PRIMIMMUNO)
This clinical trial update examines how delaying initiation of combined antiretroviral therapy (cART) in primary HIV infection affects immun…
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CLINICAL_TRIALS research · 2016-07-12Clinical Trial Update: Physiopathology Study of the Microbiota Biodiversity of HIV Seropositive Patients
Completed clinical study examining the physiology and microbiota biodiversity in HIV-1 seropositive patients.
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Evaluation of Simplified Antiretroviral Treatment Strategies in HIV Infected Children Treated by Antiretroviral (ARV) Before One Year of Age [Phase 2, Phase 3]
This update reports on a Phase 2/3 trial evaluating simplified antiretroviral treatment strategies in HIV-infected children treated with ARV…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Assessing the Severity of Metabolic-related Liver Injuries in Aging HIV-monoinfected Patients [NA]
A completed clinical trial evaluating the severity of metabolic-related liver injuries in aging HIV-monoinfected patients.
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CLINICAL_TRIALS research · 2016-07-12Clinical Trial Update: A Cross Sectional Evaluation of the Development in Children Age 4 to 7 Infected or Exposed to HIV From the ANRS 12140 Cohort (Pediacam) [NA]
Observational cross-sectional evaluation of development in children aged 4 to 7 who are HIV-infected or HIV-exposed from the ANRS 12140 Pedi…
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CLINICAL_TRIALS research · 2016-07-11Clinical Trial Update: Vitamin D and Calcium Supplement Attenuate Bone Loss Among HIV- Infected Patients Receiving Tenofovir Disoproxil Fumarate, Lamivudine or Emtricitabine and Efavirenz [NA]
A clinical trial update suggests vitamin D and calcium supplementation may attenuate bone loss in HIV-infected patients on tenofovir disopro…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Modulation of Immune Activation by Aspirin [Phase 2]
Phase 2 clinical trial examining aspirin's ability to modulate immune activation in HIV-1 infection; results for the completed study were po…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: A Study of Enfuvirtide (Fuzeon) in Participants With Advanced Human Immunodeficiency Virus (HIV) Infection [Phase 4]
Phase 4 study of enfuvirtide (Fuzeon) in participants with advanced HIV infection has completed with results posted in 2016.
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: Epicardial Adipose Tissue And Coronary Risk In HIV-Infected Patients [NA]
This document notes the completion of a clinical trial evaluating epicardial adipose tissue and coronary risk in HIV-infected patients. No s…
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: PET/CT in Extrapulmonary TB in HIV Patients: a Clinical Trial [NA]
A completed clinical trial evaluating the use of PET/CT imaging for extrapulmonary tuberculosis in HIV-infected patients. The update confirm…
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FDA approval · 2016-07-01FDA Approved: EVOTAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
FDA approved a supplemental application for EVOTAZ (atazanavir and cobicistat) to update the product labeling.
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CLINICAL_TRIALS trial_result · 2016-06-29Clinical Trial Update: A Prospective, With One Site, Open-label Not Controled Trial, for the Observation of Treatment With CIDOFOVIR 1%, 3 Nights Per Week, During 4 Weeks, of Anal Intraepithelial Neoplasia, High Level, in HIV+ Patients [NA]
A single-site, open-label, non-controlled trial evaluated topical cidofovir 1% three nights per week for four weeks in HIV-infected individu…
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CLINICAL_TRIALS research · 2016-06-29Clinical Trial Update: Observational, Retrospective, Multicenter Study to Describe the Reasons for the Change of the Regimen of Antiretroviral Therapy in HIV Patients
This completed multicenter observational, retrospective study describes the reasons why HIV patients change antiretroviral therapy regimens.
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: Vitamin D and HIV-Cardiovascular Disease in Children and Young Adults
This completed clinical trial evaluated Vitamin D supplementation (cholecalciferol) in HIV-infected children and young adults at risk of car…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Relative Oral Bioavailability Study of Different Fixed Dose Combinations of Dolutegravir and Rilpivirine in Healthy Subjects [Phase 1]
Phase 1 pharmacokinetic study evaluating relative oral bioavailability of different fixed-dose combinations of dolutegravir and rilpivirine …
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CLINICAL_TRIALS trial_result · 2016-06-24Clinical Trial Update: Preservation and Expansion of T-cell Subsets Following HAART De-intensification to Atazanavir/Ritonavir (ATV/r) [NA]
This clinical trial update reports on the preservation and expansion of T-cell subsets after de-intensifying HAART to atazanavir/ritonavir (…
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Test of an Intervention to Improve HIV Care [NA]
A clinical trial evaluating an intervention to improve HIV care has completed.