HIV Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
A completed pilot study investigated biomarkers related to HIV infection and tobacco use among injection drug users in Baltimore, highlighti…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Daclizumab to Treat HIV-Infected Patients [Phase 1]
A Phase 1 study by NIAID evaluating daclizumab in HIV-infected patients has completed.
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FDA approval · 2017-06-29FDA Approved: NORVIR — Supplemental Application (AbbVie Inc.)
FDA approved a supplemental application for NORVIR (ritonavir) submitted by AbbVie Inc.
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infection [Phase 2]
Phase 2 pilot trial assessing the efficacy and safety of the fixed-dose combination sofosbuvir/ledipasvir in treatment-experienced patients …
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FDA approval · 2017-06-29FDA Approved: NORVIR — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for NORVIR (ritonavir) submitted by AbbVie Inc., updating labeling for the product.
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating whether vorinostat can induce HIV RNA expression in resting CD4+ T cells of HIV-infected individuals on sta…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Toll-like Receptor 9 Agonist Treatment in Chronic HIV-1 Infection [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a Toll-like receptor 9 agonist for chronic HIV infection has completed. The snippet does not include t…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Effect of Antacids on the Pharmacokinetics of Raltegravir [Phase 1]
This Phase 1 trial evaluated whether antacids alter the pharmacokinetics of raltegravir in HIV infection.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Improving Memory Performance by Applying Cognitive Training [NA]
A completed Duke University clinical trial studied whether cognitive training can improve memory in people living with HIV. The results were…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Renal Integrase Study [Phase 4]
Phase 4 clinical trial update on a renal integrase study in HIV patients; the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: An Interactive Game for HIV Prevention in Early Adolescents [NA]
This entry notes the completion of a Yale University–sponsored clinical trial evaluating an interactive game designed to prevent HIV infecti…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: The Pharmacology/Aging Clinic
A completed clinical trial update from the Pharmacology/Aging Clinic related to HIV infection.
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA. [Phase 1]
This Phase 1 study in healthy volunteers evaluated the safety and metabolism of different doses of the long-acting HIV drug TMC278LA. The tr…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Managing Medications [NA]
A completed clinical trial update from the University of Pittsburgh focusing on managing medications for HIV infection. The snippet provides…
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CLINICAL_TRIALS research · 2017-06-21Clinical Trial Update: Pharmacokinetics of Efavirenz in the Presence of Rifampicin and Isoniazid [Phase 1]
Phase 1 study assessing how rifampicin and isoniazid alter the pharmacokinetics of efavirenz in people with HIV.
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1 [Phase 4]
A Phase 4 HIV trial comparing saquinavir plus lopinavir/ritonavir with enfuvirtide to saquinavir plus lopinavir/ritonavir with other nucleos…
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FDA approval · 2017-06-19FDA Approved: PREZISTA — Supplemental Application (Janssen Products LP)
The FDA approved a supplemental application for PREZISTA (darunavir) submitted by Janssen Products LP.
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FDA approval · 2017-06-19FDA Approved: PREZISTA — Supplemental Application (Janssen Products LP)
FDA approved a supplemental application for Prezista (darunavir) submitted by Janssen Products LP.
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients. [Phase 4]
Phase IV, open-label, single-arm study evaluating the pharmacokinetics and pharmacodynamics of the antiretroviral combination rilpivirine pl…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Naltrexone for Medication Compliance Among HIV-infected Men With Alcohol Use Disorder [Phase 4]
Phase 4 trial evaluating naltrexone to improve medication compliance in HIV-infected men with alcohol use disorder; the study has completed.
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FDA approval · 2017-06-15FDA Approved: KALETRA — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for KALETRA (lopinavir/ritonavir) from AbbVie Inc.
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FDA approval · 2017-06-15FDA Approved: KALETRA — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for KALETRA (lopinavir/ritonavir) submitted by AbbVie Inc., resulting in updated labeling for th…
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FDA approval · 2017-06-14FDA Approved: PREZCOBIX — Supplemental Application (Janssen Products, LP)
The FDA approved a supplemental application for PrezcoBix (darunavir ethanolate and cobicistat) from Janssen Products LP.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: HIV Reservoir Dynamics After Switching to Dolutegravir in Patients on a PI and 2 NRTI Based Regimen [Phase 4]
This Phase 4 trial update reports on HIV reservoir dynamics after switching from a protease inhibitor plus two NRTIs to dolutegravir in viro…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla [Phase 4]
A Phase 4 trial comparing switching from Atripla to Eviplera versus continuing Atripla, examining changes in plasma lipid profiles in HIV-1–…