HIV Infection
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: Growing Up: Intervening With HIV-Positive Adolescents in Resource-Poor Settings [NA]
A completed clinical trial conducted by Florida International University on interventions for HIV-positive adolescents in resource-poor sett…
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CLINICAL_TRIALS research · 2018-07-11Clinical Trial Update: Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM). [NA]
A completed clinical trial evaluating a counseling and problem-solving intervention to improve adherence to HIV pre-exposure prophylaxis (Pr…
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FDA approval · 2018-07-10FDA Approved: CIMDUO — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for Cimduo (lamivudine and tenofovir disoproxil fumarate) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Neuropsychiatric Side Effects of Efavirenz in Children Living With HIV
Completed clinical trial assessing neuropsychiatric side effects of efavirenz in children with HIV.
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: A Comprehensive Approach to Secondary HIV Prevention and Care Among Positives [NA]
This entry reports the completion of a Johns Hopkins-led clinical trial evaluating a comprehensive approach to secondary HIV prevention and …
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Antiretroviral Drug Interaction Study in Volunteers With HIV [Phase 1]
Phase 1 trial evaluating interactions between antiretroviral drugs in volunteers with HIV; study has been completed.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Switching From Efavirenz/Atripla to Rilpivirine Among Patients With Neurocognitive or Neuropsychological Side Effects [Phase 4]
Phase 4 study evaluating switching HIV-1 infected patients with neurocognitive or neuropsychological side effects from efavirenz/Atripla to …
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Lymphocyte Infusions for the Treatment of HIV-Infected Patients Failing Anti-HIV Therapy [Phase 1]
Phase 1 study of lymphocyte infusions for HIV-infected patients failing antiretroviral therapy has been terminated.
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Dolutegravir-based Dual Therapies in HIV-infected Patients With Virological Suppression
Clinical trial update about switching virologically suppressed HIV patients to dolutegravir-based two-drug regimens; the study has completed…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Prevalence of Vertebral Fractures in HIV Infected Patients Older Than 50 Years
Clinical trial update reporting the prevalence of vertebral fractures in HIV-infected patients over 50; the study has completed.
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FDA approval · 2018-07-02FDA Approved: EMTRICITABINE — Original Application (Cipla USA Inc.)
FDA approved Cipla USA Inc.'s original application for generic emtricitabine, enabling its use in HIV-1 treatment regimens.
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: An Observational Retrospective Database Analysis to Evaluate Raltegravir Based-regimens in Aged HIV Patients (RalAge)
This completed observational retrospective database analysis evaluates raltegravir-based regimens in older adults living with HIV. The study…
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: HIV and Ovarian Reserve [NA]
An update on a clinical trial examining HIV and ovarian reserve. The study status is UNKNOWN and no phase information is provided.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers [Phase 2]
A Phase 2 clinical trial evaluated the effects of Visbiome Extra Strength probiotic on the gut microbiome and immune activation markers in H…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV) [Phase 2]
BLIR-HIV is a Phase 2 trial evaluating bone loss and immune reconstitution in people with HIV/AIDS; results were posted after the study comp…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Evaluation of Low-dose Darunavir in a Switch Study [Phase 3]
A Phase 3 trial evaluating a low-dose darunavir in a switch strategy for HIV infection has completed.
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FDA approval · 2018-06-25FDA Approved: ATAZANAVIR SULFATE — Original Application (Aurobindo Pharma Limited)
FDA approved an original abbreviated new drug application for atazanavir sulfate from Aurobindo Pharma Limited. Atazanavir is used in the tr…
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FDA approval · 2018-06-22FDA Approved: APTIVUS — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
FDA approved a supplemental application for APTIVUS (tipranavir) by Boehringer Ingelheim Pharmaceuticals, expanding its labeling.
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Effect of Supplementation of Bioactive Compounds on the Energy Metabolism of People Living With HIV / AIDS [NA]
This completed clinical trial evaluated the effect of supplementing bioactive compounds on energy metabolism in people living with HIV/AIDS.
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Linking Infectious and Narcology Care in Russia [NA]
Completed clinical trial evaluating the integration of infectious disease care with addiction (narcology) services in Russia for individuals…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: ZIAGEN® Post-marketing Surveillance
This document reports the completion of a post-marketing surveillance study for ZIAGEN (abacavir) sponsored by ViiV Healthcare.
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CLINICAL_TRIALS trial_result · 2018-06-18Clinical Trial Update: Evaluation of an Integrated Economic Strengthening and HIV Prevention Program for Vulnerable Youth in South Africa [NA]
The trial evaluating an integrated economic strengthening and HIV prevention program for vulnerable youth in South Africa has completed, acc…
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FDA approval · 2018-06-15FDA Approved: ISENTRESS — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for Isentress (raltegravir) submitted by Merck Sharp & Dohme LLC, resulting in an approved regul…
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FDA approval · 2018-06-15FDA Approved: EFAVIRENZ — Original Application (Cipla USA Inc.)
FDA approved the original application for efavirenz from Cipla USA Inc. as a generic version for HIV-1 infection. This marks another entry i…
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: TMAO and Atherosclerosis in HIV
The trial investigated the relationship between TMAO and atherosclerosis in people with HIV, focusing on carotid artery plaque, and has comp…