HIV Infection
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CLINICAL_TRIALS trial_result · 2019-02-22Clinical Trial Update: HIV Testing in Pregnant Women: Evaluating an Opt-Out Testing Strategy
The completed trial evaluated an opt-out HIV testing strategy in pregnant women to determine if it increases testing uptake compared with st…
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CLINICAL_TRIALS trial_result · 2019-02-22Clinical Trial Update: Fetal HIV Transmission Risk and Duration of Membrane Rupture
This clinical trial update notes the completion of a study assessing fetal HIV transmission risk and how it relates to the duration of membr…
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CLINICAL_TRIALS trial_result · 2019-02-22Clinical Trial Update: Bioavailability of Doravirine (MK-1439) Experimental Nano Formulations in Healthy Adults (MK-1439-046) [Phase 1]
Phase 1 study evaluating bioavailability of experimental nano formulations of doravirine (MK-1439) in healthy adults has completed with resu…
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CLINICAL_TRIALS research · 2019-02-22Clinical Trial Update: HIV Physician's Survey
A completed clinical trial survey gathering information from HIV physicians about HIV management practices and perspectives.
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CLINICAL_TRIALS research · 2019-02-22Clinical Trial Update: Understanding HIV Susceptibility in the Female Genital Tract
A completed clinical trial studying HIV susceptibility in the female genital tract, sponsored by Unity Health Toronto. The trial status is C…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Safer Sex Program for Young African-American Men [Phase 2]
Phase 2 clinical trial evaluating a safer sex program for young African-American men has completed. The study targeted prevention of sexuall…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Bioequivalence Study of Fixed Dose Versus Single Entities of Dolutegravir and Lamivudine [Phase 1]
Phase 1 bioequivalence trial comparing fixed-dose dolutegravir/lamivudine to the two drugs given separately in people with HIV infection; re…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Implementing a Comprehensive Prevention of Mother-to-Child Transmission of HIV Program for South African Couples [NA]
Clinical trial update on implementing a comprehensive prevention of mother-to-child transmission of HIV program for South African couples; r…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Switching From a Tenofovir Disoproxil Fumarate (TDF) Containing Regimen to Elvitegravir/Cobicistat/Emtricitabine/ Tenofovir Alafenamide (E/C/F/TAF) Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Adults Aged ≥ 60 Years [Phase 3]
Phase 3 trial evaluating switching virologically suppressed adults aged 60+ from TDF-containing regimens to the single-tablet regimen E/C/F/…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Same-day ART Initiation Versus Standard of Care After Positive HIV-test Result in Rural Lesotho [Phase 3]
Phase 3 trial in rural Lesotho comparing same-day initiation of antiretroviral therapy after a positive HIV test to standard of care; the st…
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CLINICAL_TRIALS research · 2019-02-18Clinical Trial Update: Prospective Evaluation of HIV Patients Using Non-invasive Methods for Estimation of Liver Fibrosis and Steatosis
Prospective clinical trial in HIV patients evaluating non-invasive methods to estimate liver fibrosis and steatosis.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Efficacy of GZR/EBR in Early Chronic Hepatitis C in HIV/HCV Co-infected Patients [Phase 3]
Phase 3 trial evaluating the efficacy of grazoprevir/elbasvir in early chronic hepatitis C among HIV/HCV co-infected patients.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Evaluation of Compliance With Treatment by Genvoya in HIV Post-exposure Prophylaxis [Phase 3]
This trial update reports on adherence to Genvoya used for HIV post-exposure prophylaxis in a Phase 3 study that has completed.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study [Phase 3]
Completed Phase 3 cohort study evaluating pentamidine prophylaxis to prevent relapses of visceral leishmaniasis in HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: A Study of Doravirine (MK-1439) in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Participants (MK-1439-005) [Phase 1]
Phase 1 study of doravirine (MK-1439) in HIV-1-infected participants has completed, with results posted.
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection [Phase 2]
A Phase 2 clinical trial compares the RIPE tuberculosis regimen alone versus RIPE with added N-acetylcysteine in patients co-infected with H…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Neuropsyquiatric Evolution After Introduction of Raltegravir QD in Substitution of Dolutegravir: NEAR QD Study [Phase 4]
Phase 4 trial evaluating neuropsychiatric outcomes after substituting dolutegravir with raltegravir in HIV infection.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Integrating ENGagement and Adherence Goals Upon Entry iENGAGE to Control HIV [NA]
This completed clinical trial evaluated the iENGAGE program, which integrates engagement and adherence goals to help control HIV.
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: Identification and Quantification of HIV CNS Latency Biomarkers
This clinical trial explores identifying and quantifying biomarkers of HIV central nervous system latency, sponsored by St Vincent's Hospita…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine Among HIV-infected Adults [Phase 4]
Phase 4 study assessing immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine (PCV13) in HIV-infected adults.
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Prospective Non-Interventional Observational Study of Use of TRIUMEQ and Corresponding Monitoring Measures in Clinical Practice in Germany
A completed prospective non-interventional observational study examining the real-world use of TRIUMEQ and monitoring in clinical practice i…
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Randomized Placebo-controlled Pilot Trial of Prebiotics+Glutamine in HIV Infection [Phase 1, Phase 2]
This report documents the completion of a randomized, placebo-controlled pilot trial evaluating prebiotics in combination with glutamine for…
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CLINICAL_TRIALS research · 2019-02-11Clinical Trial Update: A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods [NA]
A clinical trial update describing a study to evaluate acceptability and preference for contraceptive options as proxies for HIV prevention …
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV [Phase 1]
Phase 1 trial evaluating autologous T cells genetically modified to disrupt CCR5 using zinc finger nucleases (SB-728) for HIV. The study sta…
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Differentiated Care for Improved Health Systems Efficiency and Health Outcomes in Zambia [NA]
The clinical trial in Zambia completed, evaluating differentiated care approaches to improve health system efficiency and HIV-related health…