HIV Infection
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Open Label, Pilot Study of Darunavir Boosted by Cobicistat in Combination With Rilpivirine to Treat HIV+ Naïve Subjects [Phase 4]
An open-label Phase 4 pilot trial is evaluating a regimen of darunavir boosted by cobicistat in combination with rilpivirine for treatment-n…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Comparing the Effectiveness Between Ritonavir Boosted Atazanavir and Efavirenz for the First HIV Treatment [Phase 3]
A Phase 3 trial update comparing ritonavir-boosted atazanavir with efavirenz as initial HIV therapy has completed.
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Comparison of Epzicom and Truvada for the Initial Once Daily HIV Treatment [Phase 4]
This update reports completion of a Phase 4 trial comparing Epzicom versus Truvada for initial once-daily HIV treatment.
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Comparing Continuing Tenofovir, Emtricitabine (or Lamivudine) Plus Lopinavir and Switching to Raltegravir Plus Darunavir [NA]
A completed clinical trial comparing continuing Tenofovir disoproxil fumarate with Emtricitabine (or Lamivudine) plus Lopinavir versus switc…
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Lopinavir/Ritonavir (LPV/r) Tablet in HIV Infected Children [Phase 2]
An update on a Phase 2 trial evaluating the Lopinavir/ritonavir tablet in HIV-infected children, with the study status listed as completed.
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Lopinavir/Ritonavir Monotherapy in Children [Phase 4]
Phase 4 trial results update on lopinavir/ritonavir monotherapy in HIV-infected children. The report summarizes safety and efficacy outcomes…
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Simultaneous Versus Sequential Antiretroviral Therapy (ARV) Therapy and Mycobacterium Tuberculosis (MTB) Treatment [NA]
The clinical trial comparing simultaneous versus sequential antiretroviral therapy and tuberculosis treatment was terminated.
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Pediatric Study for Appropriate Dose of Ritonavir Boosted Lopinavir in Thai HIV-infected Children (PEARL) [Phase 3]
Phase 3 pediatric dosing study (PEARL) evaluated the appropriate ritonavir-boosted lopinavir dose in Thai HIV-infected children; the trial h…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Evaluating the Safety and Priming Response of an HIV Vaccine Regimen in Healthy, HIV-Uninfected Adults [Phase 1]
This Phase 1 trial update reports safety outcomes and priming immune responses for an HIV vaccine regimen in healthy, HIV-uninfected adults.
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: IMPAACT P1074: Long-Term Outcomes in HIV-Infected Infants, Children, and Adolescents
Clinical trial update reporting long-term outcomes from the IMPAACT P1074 study in HIV-infected infants, children, and adolescents, with ext…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Phase II Randomized Study of Physiologic Testosterone Replacement in Premenopausal, HIV-Positive Women [Phase 2]
Phase II randomized study of physiologic testosterone replacement in premenopausal HIV-positive women has completed. The trial investigates …
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Study to Evaluate Changes in CD4 on Replacing TDF With ABC or DDI+TDF With ABC+3TC [Phase 3]
Phase 3 trial evaluating CD4 cell count changes after replacing tenofovir disoproxil fumarate with abacavir, or replacing didanosine + TDF w…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Enhanced Prevention in Couples: Feasibility Study #2
This document reports the completion of feasibility study #2 on enhanced prevention in couples for HIV/AIDS. The study was sponsored by Colu…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Enhanced HIV Prevention in Couples: Feasibility Study #1
This is a completed feasibility study update on enhanced HIV prevention in couples (NCT02027714).
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: The First Failure Study [Phase 4]
A Phase 4 HIV trial titled 'The First Failure Study' (NCT01118871) conducted by Imperial College London was terminated. No results are provi…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Evaluating a Microfinance Intervention for High Risk Women in Mongolia [NA]
This document provides an update on a completed clinical trial in Mongolia evaluating a microfinance intervention for high-risk women to inf…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Assessing HIV-Related Oral Mucosal Disease and Using Saliva to Measure Viral Load
This update reports on a completed clinical trial investigating HIV-related oral mucosal disease and the use of saliva to measure HIV viral …
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Observational Study of Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals
An observational study evaluating the specificity of tuberculosis screening and diagnostic tests in people with HIV infection. The study sta…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: A Study of Dementia and Neurological Problems in HIV Infected Patients Who Are Participating in ACTG A5175
This ClinicalTrials.gov entry reports on dementia and neurological problems in HIV-infected patients enrolled in ACTG A5175; the trial has c…
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: A Study to Treat Subjects With Telaprevir, Ribavirin, and Peginterferon Who Are Coinfected With HIV and Hepatitis C Virus (HCV) [Phase 3]
Phase 3 study evaluating telaprevir with ribavirin and peginterferon for HIV/Hepatitis C coinfection was terminated, with results posted in …
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CLINICAL_TRIALS trial_result · 2015-03-13Clinical Trial Update: Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients [Phase 1]
This update reports the completion of a Phase 1 dose-escalation study in HIV-infected patients using autologous T-cells edited at the CCR5 g…
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CLINICAL_TRIALS trial_result · 2015-03-11Clinical Trial Update: Pilot Opened Trial in HIV-infected Patients Including an Investigational Marketed Product [Phase 4]
A Phase 4 pilot open-label trial in HIV-infected patients evaluating an investigational use of a marketed product.
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CLINICAL_TRIALS trial_result · 2015-03-10Clinical Trial Update: Efficacy and Safety of Temazepam in HIV Seropositive Patients With Insomnia [Phase 4]
Phase 4 results evaluate the efficacy and safety of temazepam for treating insomnia in HIV-positive individuals.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Increasing HAART-Induced Immune Restoration With Cyclosporine [Phase 2]
Phase 2 trial evaluating cyclosporine to boost immune restoration in HIV patients receiving HAART; status completed.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: A Study of the Safety and Effectiveness of an HIV Vaccine for HIV-Positive Patients Receiving Anti-HIV Drugs for at Least 2 Years [Phase 1]
Phase 1 clinical trial update evaluating the safety and effectiveness of an HIV vaccine in HIV-positive patients on antiretroviral therapy f…