HIV Infection
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: Antiretroviral Adherence Evaluation in HIV Pregnant and Postpartum Women
This update notes the completion of a clinical trial evaluating adherence to antiretroviral therapy among HIV-infected pregnant and postpart…
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Vicriviroc in HIV(R5/X4)-Treatment Experienced Subjects (Study P05057AM5)(COMPLETED) [Phase 2]
This is an update on a completed Phase 2 trial of vicriviroc in treatment-experienced HIV-infected subjects.
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: A Phase II/III Trial of Lopinavir/Ritonavir Dosed According to the WHO Pediatric Weight Band Dosing Guidelines [Phase 2, Phase 3]
Phase II/III trial evaluating lopinavir/ritonavir dosing according to WHO pediatric weight-band guidelines in HIV; study completed with resu…
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Bryostatin-1 Effect on HIV-1 Latency and Reservoir in HIV-1 Infected Patients Receiving Antiretroviral Treatment [Phase 1]
Phase 1 clinical trial evaluating Bryostatin-1 for its effect on HIV-1 latency and reservoirs in patients on antiretroviral therapy has been…
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Effect of Cytoreductive Chemotherapy and a CCR5 Coreceptor Antagonist on HIV-1 Eradication [EARLY_Phase 1]
An early-phase HIV eradication trial combining cytoreductive chemotherapy with a CCR5 coreceptor antagonist was terminated before completion…
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Safety and Efficacy Study of Daclatasvir (BMS-790052) Plus Pegylated Interferon-Alfa 2a and Ribavirin in Patients Coinfected With Untreated Hepatitis C Virus and HIV Virus [Phase 3]
Phase 3 safety and efficacy study of daclatasvir with pegylated interferon alfa-2a and ribavirin in patients with untreated hepatitis C geno…
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: Feasibility of Measuring Immune Resp, Activation in Foreskin/Mucosa in HIV-, Uncircumcised High-HIV-risk MSM, Lima Peru [NA]
The NIAID-sponsored study completed a feasibility assessment for measuring immune activation in foreskin/mucosal tissue among HIV-negative, …
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Study of Maraviroc (MVC) and Epzicom (ABC/3TC) Once-Daily in ART-Naive & First Switch Patients
A completed study evaluating once-daily maraviroc with Epzicom (abacavir/lamivudine) in ART-naive and first-switch HIV patients.
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment [Phase 3]
A Phase 3 trial compared once-daily darunavir/ritonavir monotherapy to a triple regimen including darunavir/ritonavir in HIV patients with u…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: HIV Prevention Among Substance Abusing SMI [Phase 3]
Phase 3 clinical trial evaluating HIV prevention in individuals with serious mental illness and substance use disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: The Role of Genital Warts in HIV Acquisition in Peru
This completed clinical trial examined whether genital warts influence HIV acquisition risk among participants in Peru.
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Safety Sudy of Atazanavir Boosted With Ritonavir in the Treatment of HIV Infection in Pediatric Patients [Phase 4]
Phase 4 safety study evaluating atazanavir boosted with ritonavir for HIV infection in pediatric patients; results have been posted.
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Multicentre Study To Assess Changes In Bone Mineral Density Of The Switch From Protease Inhibitors To Dolutegravir In HIV-1-Infected Subjects With Low Bone Mineral Density [Phase 3]
A Phase 3 multicenter trial assessing changes in bone mineral density after switching from protease inhibitors to dolutegravir in HIV-1-infe…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Pediatric Expanded Access Program-Oral Solution (0831-908) [Phase 3]
This document reports the completion of a pediatric expanded access program for an oral solution (0831-908) sponsored by Merck for HIV infec…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Immune Activation in HIV-1 Infected Patients Under AntiRetroviral Treatment [NA]
Completed clinical trial evaluating immune activation in HIV-1 infected patients on antiretroviral therapy. The study explored activation of…
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Nevirapine Dosing in Neonates for Prophylaxis of Mother-to-Child-Transmission (MTCT) of HIV Infection
This clinical trial studied nevirapine dosing in neonates to prevent mother-to-child transmission of HIV and has completed.
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) [Phase 2, Phase 3]
Clinical trial update for the SOCA HPCRT study evaluating HPMPC (cidofovir) for CMV retinitis in HIV/AIDS patients; the Phase 2/Phase 3 tria…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) [Phase 2, Phase 3]
Phase 2/3 trial evaluating a CMV-specific monoclonal antibody for ocular complications in AIDS patients with Cytomegalovirus retinitis; resu…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Anal HPV Infection and Abnormal Cytology in HIV-infected Women
Clinical trial completed investigating anal HPV infection and abnormal cytology in HIV-infected women.
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Effect of a Micro-finance-based Intervention for the Prevention of Intimate-partner Violence and HIV [NA]
A clinical trial evaluating a micro-finance–based intervention to prevent intimate-partner violence and HIV infection has completed. Sponsor…
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CLINICAL_TRIALS trial_result · 2015-11-13Clinical Trial Update: Bioequivalence Study Between Lamivudine Formulations in the Form of Coated Tablet of 150 mg in Healthy Volunteers [Phase 1]
A Phase 1 bioequivalence study comparing two 150 mg lamivudine coated tablet formulations in healthy volunteers has been completed.
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CLINICAL_TRIALS trial_result · 2015-11-11Clinical Trial Update: Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life Conditions
This clinical trial update assesses the hepatic safety of currently used antiretroviral regimens in patients with chronic hepatitis and HIV …
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg [Phase 4]
A Phase 4 randomized trial evaluating the concomitant use of rifampicin and efavirenz for TB and HIV co-infection was terminated.
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda [Phase 2, Phase 3]
Phase 2/3 trial update on enhanced provision of neonatal male circumcision as an HIV prevention strategy in Rakai, Uganda; trial status is c…
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Traditional CAM Therapy in the Treatment of HIV/AIDS [Phase 1, Phase 2]
A traditional CAM therapy being studied for HIV infection in a Phase 1/2 trial has been terminated. No efficacy results are provided.