HIV Infection

• CLINICAL_TRIALS trial_result · 2016-11-30
  Clinical Trial Update: Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF [Phase 3]

  Phase 3 switch study evaluating F/TAF in HIV-1 patients virologically suppressed on regimens containing FTC/TDF has completed with results p…

• CLINICAL_TRIALS trial_result · 2016-11-30
  Clinical Trial Update: Folinic Acid: Supplementation and Therapy [Phase 3]

  The document reports the completion of a Phase 3 trial evaluating folinic acid supplementation and therapy in individuals with HIV infection…

• CLINICAL_TRIALS trial_result · 2016-11-30
  Clinical Trial Update: The PreNAPS Study: FI, Nutrition, and Psychosocial Health Outcomes at Gulu Regional Referral Hospital

  The PreNAPS study at Gulu Regional Referral Hospital completed, evaluating food insecurity, nutrition, and psychosocial health outcomes in p…

• CLINICAL_TRIALS trial_result · 2016-11-29
  Clinical Trial Update: Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds [Phase 4]

  Phase 4 trial update evaluating interferon alfa sensitivity in HIV/Hepatitis C–coinfected individuals before and after initiation of HIV the…

• CLINICAL_TRIALS trial_result · 2016-11-28
  Clinical Trial Update: An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM) [Phase 2]

  Phase 2 results update for ES-HIM, a behavioral intervention to improve sexual health among Black men at risk for HIV.

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• CLINICAL_TRIALS trial_result · 2016-11-28
  Clinical Trial Update: Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events [Phase 4]

  Phase 4 trial examining whether immediate initiation of antiretroviral therapy improves outcomes compared with deferring treatment in HIV-in…

• CLINICAL_TRIALS trial_result · 2016-11-28
  Clinical Trial Update: Mothers Living With HIV and Their Adolescent Children [NA]

  This entry notes a completed clinical trial sponsored by UCLA investigating mothers living with HIV and how it affects family relations, men…

• CLINICAL_TRIALS trial_result · 2016-11-22
  Clinical Trial Update: Fluoride Metabolism, Bone Remodelling and Mineral Density in HIV Patients Treated With Tenofovir +/- Emtricitabine

  This is a completed clinical trial update. It evaluates fluoride metabolism, bone remodeling, and bone mineral density in HIV-infected patie…

• CLINICAL_TRIALS trial_result · 2016-11-21
  Clinical Trial Update: Trial of the Safety and Immunogenicity of an Oral, Replicating Ad26 Vectored HIV-1 Vaccine [Phase 1]

  A Phase 1 trial evaluating safety and immunogenicity of an oral replicating Ad26-vectored HIV-1 vaccine has completed.

• CLINICAL_TRIALS trial_result · 2016-11-15
  Clinical Trial Update: AIMS Study: Improving HIV Treatment Adherence [NA]

  The HIV treatment adherence trial 'AIMS' sponsored by Wageningen University has completed.

• CLINICAL_TRIALS trial_result · 2016-11-10
  Clinical Trial Update: The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo [Phase 1, Phase 2]

  This document reports an update on a Phase 1/2 trial evaluating the safety and immunogenicity of the DNA-GTU vaccine in HIV-infected adults …

• CLINICAL_TRIALS trial_result · 2016-11-08
  Clinical Trial Update: Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé) [Phase 3]

  Phase 3 clinical trial update evaluating three strategies of second-line antiretroviral treatment in Africa (Dakar, Bobo-Dioulasso, Yaoundé)…

• CLINICAL_TRIALS trial_result · 2016-11-07
  Clinical Trial Update: A Study of Zidovudine in the Prevention of HIV Infection in Individuals Exposed to the Virus [NA]

  This update reports on a completed clinical trial evaluating zidovudine (AZT) for preventing HIV infection in individuals exposed to the vir…

• CLINICAL_TRIALS trial_result · 2016-11-07
  Clinical Trial Update: A Study of HIV in Newly Infected Individuals

  A clinical trial studying HIV infection in individuals newly infected has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study Comparing the Efficacy and Safety of Once-Daily Fuzeon (Enfuvirtide) Dosing Versus the Currently Recommended Twice-Daily Dosing in Human Immunodeficiency Virus-Type 1 (HIV-1) Infected Patients [Phase 2]

  Phase 2 study comparing once-daily dosing of Fuzeon (enfuvirtide) to the standard twice-daily regimen in HIV-1 infected patients has complet…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected Patients [Phase 1]

  This Phase 1 trial evaluated ritonavir-boosted saquinavir in treatment-naive HIV-1 infected patients and has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Observational Study on Predictors of Response to Invirase (Saquinavir) Treatment in Treatment-naïve Patients With HIV Infection

  This completed observational study investigates predictors of response to saquinavir (Invirase) treatment in treatment-naïve people with HIV…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: An Observational Study of Induction Therapy With Fuzeon (Enfuvirtide) in Combination With Antiretroviral Drugs in Patients With HIV-1 Infection

  This completed observational study evaluated induction therapy with Fuzeon (enfuvirtide) in combination with other antiretroviral drugs for …

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: QUALITE Study - A Study of Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With Human Immunodeficiency Virus-1 (HIV-1) Infection [Phase 4]

  The QUALITE study evaluated enfuvirtide (Fuzeon) in treatment-experienced HIV-1 patients in Phase 4, and the trial has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Optimizing Integrated PMTCT Services in Rural North-Central Nigeria [NA]

  A completed clinical trial evaluating integrated PMTCT services in rural North-Central Nigeria.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Enfuvirtide (Fuzeon) in Patients With Advanced Human Immunodeficiency Virus-1 (HIV-1) Infection [Phase 4]

  Phase 4 clinical trial update for enfuvirtide (Fuzeon) in patients with advanced HIV-1 infection; study status completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Contingency Management in the Delivery of HAART to Drug Users in Chennai, India [Phase 2]

  Phase 2 trial update on using contingency management to improve delivery/adherence of HAART to HIV patients who are intravenous drug users i…

• CLINICAL_TRIALS trial_result · 2016-11-01
  Clinical Trial Update: Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults [Phase 3]

  Phase 3 open-label study evaluating switching from optimized darunavir-containing regimens to a fixed-dose combination of elvitegravir/cobic…

• CLINICAL_TRIALS trial_result · 2016-11-01
  Clinical Trial Update: Compassionate Use of Ibalizumab for the Treatment of HIV Infection

  This document provides an update on compassionate-use access to ibalizumab for HIV infection. It notes that the trial is no longer available…

• CLINICAL_TRIALS trial_result · 2016-10-31
  Clinical Trial Update: Evaluation of the Safety and Efficacy of Reformulated Raltegravir (MK-0518) 1200 mg Once Daily in Combination With TRUVADA™ in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-Naive Participants (MK-0518-292) [Phase 3]

  Phase 3 MK-0518-292 evaluated the safety and efficacy of reformulated raltegravir 1200 mg once daily in combination with TRUVADA in treatmen…