HIV Infection
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Effect of Antacids on the Pharmacokinetics of Raltegravir [Phase 1]
This Phase 1 trial evaluated whether antacids alter the pharmacokinetics of raltegravir in HIV infection.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Improving Memory Performance by Applying Cognitive Training [NA]
A completed Duke University clinical trial studied whether cognitive training can improve memory in people living with HIV. The results were…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Renal Integrase Study [Phase 4]
Phase 4 clinical trial update on a renal integrase study in HIV patients; the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: An Interactive Game for HIV Prevention in Early Adolescents [NA]
This entry notes the completion of a Yale University–sponsored clinical trial evaluating an interactive game designed to prevent HIV infecti…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: The Pharmacology/Aging Clinic
A completed clinical trial update from the Pharmacology/Aging Clinic related to HIV infection.
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA. [Phase 1]
This Phase 1 study in healthy volunteers evaluated the safety and metabolism of different doses of the long-acting HIV drug TMC278LA. The tr…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Managing Medications [NA]
A completed clinical trial update from the University of Pittsburgh focusing on managing medications for HIV infection. The snippet provides…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1 [Phase 4]
A Phase 4 HIV trial comparing saquinavir plus lopinavir/ritonavir with enfuvirtide to saquinavir plus lopinavir/ritonavir with other nucleos…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients. [Phase 4]
Phase IV, open-label, single-arm study evaluating the pharmacokinetics and pharmacodynamics of the antiretroviral combination rilpivirine pl…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Naltrexone for Medication Compliance Among HIV-infected Men With Alcohol Use Disorder [Phase 4]
Phase 4 trial evaluating naltrexone to improve medication compliance in HIV-infected men with alcohol use disorder; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: HIV Reservoir Dynamics After Switching to Dolutegravir in Patients on a PI and 2 NRTI Based Regimen [Phase 4]
This Phase 4 trial update reports on HIV reservoir dynamics after switching from a protease inhibitor plus two NRTIs to dolutegravir in viro…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla [Phase 4]
A Phase 4 trial comparing switching from Atripla to Eviplera versus continuing Atripla, examining changes in plasma lipid profiles in HIV-1–…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Efficacy of Tenofovir Alafenamide Versus Placebo Added to a Failing Regimen Followed by Treatment With Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Atazanavir in HIV-1 Positive, Antiretroviral Treatment-Experienced Adults [Phase 3]
Phase 3 trial evaluating tenofovir alafenamide added to a failing regimen, followed by a regimen including elvitegravir/cobicistat/emtricita…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Vaccination of HIV-1 Infected Patients With Dendritic Cells in Addition to Antiretroviral Treatment - (DALIA Trial) [Phase 1]
The DALIA trial reports completion of a Phase 1 study evaluating vaccination with dendritic cells in HIV-1 infected patients receiving antir…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: A Study to Assess the Relative Bioavailability of Tablet Formulations of GSK2248761 in Healthy Adult Subjects. SGN114435 [Phase 1]
This Phase 1 study evaluated the relative bioavailability of tablet formulations of GSK2248761 in healthy adult subjects and has completed.
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study) [NA]
The iTest clinical trial evaluated whether home HIV self-testing increases testing frequency among men who have sex with men. The study is c…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Cohort Study of Volunteers That Have Participated to Preventive HIV-1 Vaccine Trials
This entry reports a terminated cohort study of volunteers who participated in preventive HIV-1 vaccine trials, with sponsor information and…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: PENTA Fosamprenavir Study
The PENTA Fosamprenavir Study (NCT01077635) sponsored by ViiV Healthcare has completed.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Fractures Stratified by HIV and Antiretroviral Therapy (ART) Status
A clinical trial evaluating fractures in people living with HIV was completed, with analyses stratified by ART status.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: GW640385 Plus Ritonavir And NRTIs For 48 Weeks In HIV-1 Infected Adults [Phase 2]
This update reports the completion of a Phase 2 trial evaluating GW640385 in combination with ritonavir and nucleoside reverse transcriptase…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Observational Study Of A Protease Inhibitor (PI) Containing Regimen In Subjects With PI Mutations Selected During Prior Treatment With GW433908 (Fosamprenavir) [Phase 3]
Completed Phase 3 observational study evaluating a protease inhibitor–containing regimen in HIV patients with PI mutations selected during p…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: GW873140 In Combination With Kaletra In HIV Infected Subjects [Phase 2]
Phase 2 trial of GW873140 in combination with Kaletra for HIV infection was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: GW873140 In Combination With Combivir In HIV Infected Subjects [Phase 2]
A Phase 2 trial evaluating GW873140 in combination with Combivir in HIV-infected subjects has been terminated.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Effects of L-Carnitine on Postprandial Clearance of Triglyceride-rich Lipoproteins in HIV Patients on HAART [NA]
A completed clinical trial assessed whether L-Carnitine improves postprandial clearance of triglyceride-rich lipoproteins in HIV patients on…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: A Dose Ranging Study Of GW640385 Boosted With Ritonavir (Rtv) In Comparison To A RTV-Boosted Protease Inhibitor (PI) In HIV-1 Infected PI-Experienced Adults [Phase 2]
Phase 2 trial evaluating GW640385 boosted with ritonavir versus a ritonavir-boosted protease inhibitor in HIV-1 infected, protease inhibitor…