HIV Infection
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: HIV-1 Vaccine Test in Uninfected Adult Volunteers [Phase 1]
This document reports the completion of a Phase 1 HIV-1 vaccine trial in uninfected adults to evaluate safety and immune responses.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Safety and Immunogenicity of an HIV Vaccine in Normal Adult Volunteers [Phase 1]
Phase 1 clinical trial reports safety and immunogenicity data for an HIV vaccine in healthy adults, indicating tolerability and immune respo…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Phase I Study of Vaccination Schedule of Experimental HIV Vaccines [Phase 1]
Phase I study evaluating vaccination schedule of experimental HIV vaccines has completed. The update does not report efficacy results.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: HIV-1 Vaccine Booster in Previously Immunized Uninfected Adult Volunteers [Phase 1]
Phase 1 trial results evaluating a HIV-1 vaccine booster given to healthy adults who had prior HIV immunization and remained uninfected; the…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: An Open Label Non-Randomized Dose Escalating Trial to Assess Safety and Tolerability of Alb-Interferon Alfa 2b Every Two Weeks With Ribavirin Among HIV/HCV Coinfected Individuals [Phase 1]
Open-label, non-randomized Phase 1 dose-escalation trial evaluating safety and tolerability of Alb-Interferon Alfa 2b given every two weeks …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Safety and Immune Response to a Prime-Boost Vaccination Schedule in HIV-infected Patients [Phase 1]
Phase 1 clinical trial report evaluating the safety and immune response of a prime-boost vaccination schedule in HIV-infected participants.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection [Phase 1]
A Phase 1 clinical trial investigates whether combined antiretroviral therapy can identify sites of persistent HIV infection; the study has …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Immune Responses to HIV in Blood Cells in HIV-Infected and HIV-Uninfected Volunteers
This completed study investigates immune responses to HIV in blood cells, comparing HIV-infected volunteers with HIV-uninfected volunteers t…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: HLA and KIR Associations With Infectious Viral Agents in an HIV Cohort of Women (WIHS)
This clinical trial update reports associations between HLA and KIR genetic factors and infections with various viral agents in an HIV-infec…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effects of Anti-HIV Therapy on Red Blood Cells of HIV-infected Mothers and Their Infants
This completed clinical trial evaluated the effects of anti-HIV therapy on red blood cells in HIV-infected mothers and their infants, using …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effect of Leflunomide on T Cell Proliferation in HIV-Infected Patients [Phase 1]
A phase 1 clinical trial evaluated the effect of Leflunomide on T cell proliferation in people with HIV infection. The study status is compl…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Pharmacokinetic Interactions With Prednisolone in Healthy Volunteers and HIV-infected Patients Receiving Single-Dose Prednisone
A pharmacokinetic study reports on interactions between prednisolone and prednisone in healthy volunteers and HIV-infected patients receivin…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: The Interaction of Two HIV Medications With Blood Clot Medications in Healthy Volunteers [Phase 1]
Phase 1 study in healthy volunteers evaluating potential pharmacokinetic and safety interactions between two HIV therapies and medications u…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Differences in Blood Levels of Nevirapine in HIV-infected Patients in Uganda and the United States [Phase 4]
A Phase 4 clinical trial comparing nevirapine blood levels in HIV-infected patients in Uganda and the United States to assess pharmacokineti…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Vaccine Treatment for HIV-Infection [Phase 1]
A Phase 1 clinical trial of an HIV vaccine in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Accuracy of Hemoglobin A1C to Predict Glycemia in HIV
This clinical trial assesses whether Hemoglobin A1C can accurately predict glycemia in people with HIV, including those with diabetes. The s…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Study of Tests to Evaluate Effectiveness of Anti-HIV Drugs
This document reports an update on a completed clinical trial evaluating tests to gauge the effectiveness of anti-HIV drugs. The study focus…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy Volunteers [Phase 4]
A Phase 4 clinical trial update examining how the MDR1 genotype influences blood levels of HIV protease inhibitors indinavir and saquinavir …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma
A completed clinical trial evaluating brain lesions in HIV-infected patients to aid in the diagnosis of primary central nervous system lymph…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Changes in HIV Viral Load in Patients Undergoing Treatment for Filariasis
This completed clinical trial report examines changes in HIV viral load in patients undergoing treatment for filariasis, sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Evaluation and Monitoring of Patients With HIV Infectionn
The clinical trial NCT00557570 has completed and provides information on evaluation and monitoring of patients with HIV infection.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Daclizumab to Treat HIV-Infected Patients [Phase 1]
A Phase 1 study by NIAID evaluating daclizumab in HIV-infected patients has completed.
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infection [Phase 2]
Phase 2 pilot trial assessing the efficacy and safety of the fixed-dose combination sofosbuvir/ledipasvir in treatment-experienced patients …
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating whether vorinostat can induce HIV RNA expression in resting CD4+ T cells of HIV-infected individuals on sta…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Toll-like Receptor 9 Agonist Treatment in Chronic HIV-1 Infection [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a Toll-like receptor 9 agonist for chronic HIV infection has completed. The snippet does not include t…