HIV Infection
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Implementing a Comprehensive Prevention of Mother-to-Child Transmission of HIV Program for South African Couples [NA]
Clinical trial update on implementing a comprehensive prevention of mother-to-child transmission of HIV program for South African couples; r…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Switching From a Tenofovir Disoproxil Fumarate (TDF) Containing Regimen to Elvitegravir/Cobicistat/Emtricitabine/ Tenofovir Alafenamide (E/C/F/TAF) Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Adults Aged ≥ 60 Years [Phase 3]
Phase 3 trial evaluating switching virologically suppressed adults aged 60+ from TDF-containing regimens to the single-tablet regimen E/C/F/…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Same-day ART Initiation Versus Standard of Care After Positive HIV-test Result in Rural Lesotho [Phase 3]
Phase 3 trial in rural Lesotho comparing same-day initiation of antiretroviral therapy after a positive HIV test to standard of care; the st…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Efficacy of GZR/EBR in Early Chronic Hepatitis C in HIV/HCV Co-infected Patients [Phase 3]
Phase 3 trial evaluating the efficacy of grazoprevir/elbasvir in early chronic hepatitis C among HIV/HCV co-infected patients.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Evaluation of Compliance With Treatment by Genvoya in HIV Post-exposure Prophylaxis [Phase 3]
This trial update reports on adherence to Genvoya used for HIV post-exposure prophylaxis in a Phase 3 study that has completed.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study [Phase 3]
Completed Phase 3 cohort study evaluating pentamidine prophylaxis to prevent relapses of visceral leishmaniasis in HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: A Study of Doravirine (MK-1439) in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Participants (MK-1439-005) [Phase 1]
Phase 1 study of doravirine (MK-1439) in HIV-1-infected participants has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Neuropsyquiatric Evolution After Introduction of Raltegravir QD in Substitution of Dolutegravir: NEAR QD Study [Phase 4]
Phase 4 trial evaluating neuropsychiatric outcomes after substituting dolutegravir with raltegravir in HIV infection.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Integrating ENGagement and Adherence Goals Upon Entry iENGAGE to Control HIV [NA]
This completed clinical trial evaluated the iENGAGE program, which integrates engagement and adherence goals to help control HIV.
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine Among HIV-infected Adults [Phase 4]
Phase 4 study assessing immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine (PCV13) in HIV-infected adults.
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Prospective Non-Interventional Observational Study of Use of TRIUMEQ and Corresponding Monitoring Measures in Clinical Practice in Germany
A completed prospective non-interventional observational study examining the real-world use of TRIUMEQ and monitoring in clinical practice i…
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Randomized Placebo-controlled Pilot Trial of Prebiotics+Glutamine in HIV Infection [Phase 1, Phase 2]
This report documents the completion of a randomized, placebo-controlled pilot trial evaluating prebiotics in combination with glutamine for…
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV [Phase 1]
Phase 1 trial evaluating autologous T cells genetically modified to disrupt CCR5 using zinc finger nucleases (SB-728) for HIV. The study sta…
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Differentiated Care for Improved Health Systems Efficiency and Health Outcomes in Zambia [NA]
The clinical trial in Zambia completed, evaluating differentiated care approaches to improve health system efficiency and HIV-related health…
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection [Phase 1]
A Phase 1 study evaluating topical ABI-1968 in subjects with precancerous anal lesions caused by HPV has completed.
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: PET/CT Imaging Companion Study To ACTG A5314
Update on a PET/CT imaging companion study to ACTG A5314 in HIV; the trial has completed and results were posted on 2019-02-06.
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade [NA]
A completed clinical trial examining the role of opioid blockade in risky decision making among methamphetamine users, with comorbidity of H…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Men Together Making a Difference: Health Promotion for Black Men [NA]
Completed status update for the University of Pennsylvania–sponsored trial 'Men Together Making a Difference: Health Promotion for Black Men…
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected [Phase 1, Phase 2]
Phase 1/2 trial comparing protease inhibitor–based ART to a non-nucleoside reverse transcriptase inhibitor–based ART for clearance of Plasmo…
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Phase 4 Study of Dolutegravir (DTG) in Russian Federation [Phase 4]
A Phase 4 clinical trial evaluating dolutegravir for HIV infection in the Russian Federation has completed.
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Regular HIV Testing Among At-Risk Latino Men [NA]
Completed clinical trial evaluating regular HIV testing among at-risk Latino men; the provided snippet notes completion but does not disclos…
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Behavioral Economics Field Experiment in HIV Testing [NA]
A completed field experiment at Johns Hopkins University examined behavioral economics approaches to HIV testing.
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Comparative Efficacy of an Intensified Re-vaccination Scheme for Hepatitis B Virus Infection Among Patients Infected With HIV . [Phase 3]
Phase 3 clinical trial evaluating an intensified re-vaccination schedule for hepatitis B in people with HIV; the study has completed.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Trial of Ibudilast for Methamphetamine Dependence [Phase 2]
A Phase 2 trial evaluating ibudilast for methamphetamine dependence (with HIV infection) has completed and results were posted on January 30…
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: A Phase 1, Randomized Pharmacokinetics and Safety Study of Extended Duration Dapivirine Vaginal Rings [Phase 1]
This update reports the completion of a Phase 1 randomized pharmacokinetics and safety study evaluating extended-duration dapivirine vaginal…