HIV Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy and Safety of Elvitegravir / Cobicistat / Emtricitabine / Tenofovir Alafenamide as a First-line Treatment in Naïve Patients With HIV-1 Infection With Severe Immunosuppression [Phase 4]
Phase 4 trial evaluating a single-tablet regimen (elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide) as first-line therapy in trea…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Condom Performance in a Longitudinal Enhanced Assessment of User Experiences [NA]
Clinical trial update on condom performance from a longitudinal user experience study; results have been posted after completion.
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CLINICAL_TRIALS trial_result · 2020-08-04Clinical Trial Update: Latency and Early Neonatal Provision of Antiretroviral Drugs Clinical Trial [Phase 4]
Phase 4 clinical trial update on latency and early neonatal provision of antiretroviral drugs for HIV.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Continuation of Protease-Inhibitor Based Second-Line Therapy vs. Switch to B/F/TAF in Virologically Suppressed Adults [Phase 4]
A Phase 4 study comparing continuation of protease-inhibitor-based second-line therapy versus switching to B/F/TAF in virologically suppress…
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating naltrexone and nalmefene for HIV infection and alcohol use, with pain considerations; study completed …
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Virological Suppression in HIV Positive Patients Involved in a Novel Standardized Adherence Protocol [Phase 3]
A Phase 3 clinical trial reports virological suppression in HIV-positive patients under a novel standardized adherence protocol. The study i…
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CLINICAL_TRIALS trial_result · 2020-07-23Clinical Trial Update: 3BNC117 Monoclonal Antibody in HIV-infected Subjects During Treatment Interruption [Phase 2]
Phase 2 trial updates on the monoclonal antibody 3BNC117 in HIV-1 infection during treatment interruption have completed with posted results…
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CLINICAL_TRIALS trial_result · 2020-07-21Clinical Trial Update: Safety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed Dyslipidemia [Phase 3]
Phase 3 trial assessing safety, tolerability, and LDL-C reduction with evolocumab in HIV patients with hyperlipidemia/mixed dyslipidemia; co…
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: A Pharmacokinetic Study of Once Daily Efavirenz 400 mg Versus 600 mg in Thai HIV-1 Infected Subjects [Phase 2]
Phase 2 pharmacokinetic study comparing once-daily efavirenz 400 mg vs 600 mg in Thai HIV-1 infected subjects to evaluate PK differences.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: TDM of Generic Lopinavir/Ritonavir 200/50 mg [Phase 2]
Phase 2 clinical trial update on therapeutic drug monitoring (TDM) of generic lopinavir/ritonavir 200/50 mg for HIV treatment.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Pharmacokinetic Study of 2 Doses of ATV/r OD + 2 NRTIs in Thai HIV-1 Infected Patients [Phase 1, Phase 2]
Phase 1/2 pharmacokinetic study assessing two doses of ATV/r once daily plus two NRTIs in Thai HIV-1 infected patients; completed.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: The Immunogenicity of Varicella-zoster Virus Vaccine in HIV-infected Children [Phase 4]
Phase 4 trial assessing the immunogenicity of the varicella-zoster vaccine in HIV-infected children has been completed.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Therapeutic Drug Monitoring (TDM) in Generic Tenofovir/Lamivudine/Efavirenz [Phase 2]
Phase 2 trial update on therapeutic drug monitoring for a generic three-drug regimen (tenofovir/emtricitabine/efavirenz) in HIV.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Pharmacokinetics of Low Dose Raltegravir [Phase 2]
Phase 2 trial update evaluating the pharmacokinetics of low-dose raltegravir in HIV infection.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Lopinavir (LPV) Dose Reduction [Phase 1, Phase 2]
Phase 1/2 trial update examining dose reduction of Lopinavir (LPV) in HIV-1 infections.
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: Safety Study of a Tenofovir-containing Drug Regimen for the Prevention of Mother-to-child Transmission of HIV and HBV [Phase 2]
Phase 2 safety study evaluating a tenofovir-containing regimen for preventing mother-to-child transmission of HIV and hepatitis B has comple…
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CLINICAL_TRIALS trial_result · 2020-07-14Clinical Trial Update: Depression Therapy to Improve Cardiovascular Risk in HIV [NA]
Clinical trial on Depression Therapy aimed at improving cardiovascular risk in people with HIV has completed and posted results.
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CLINICAL_TRIALS trial_result · 2020-07-10Clinical Trial Update: Smartphone App and CO Self-monitoring for Smoking Cessation [Phase 4]
Phase 4 trial update on a smartphone app and carbon monoxide self-monitoring for smoking cessation; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Antiretroviral Treatment Guided by Proviral Genotype: Pilot Trial of Proof of Concept. [Phase 2]
Pilot Phase 2 trial exploring antiretroviral treatment guided by proviral genotype in HIV-1 infection.
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: A Retrospective Study to Evaluate the Safety and Efficacy of a Nucleoside-Sparing Regimen of Darunavir, Ritonavir, and Dolutegravir
A retrospective study assessing safety and efficacy of a nucleoside-sparing regimen (darunavir/ritonavir/dolutegravir) for HIV-1 infection.
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CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: HIV Persistence and Viral Reservoirs [Phase 4]
Clinical trial update (Phase 4) on HIV persistence and viral reservoirs; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules [Phase 4]
A multicenter Phase 4 trial reports tolerability of once-daily lopinavir/ritonavir liquid compared with capsules in HIV infection.
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CLINICAL_TRIALS trial_result · 2020-06-24Clinical Trial Update: Buprenorphine to Improve HIV Care Engagement and Outcomes [Phase 4]
Phase 4 trial investigating buprenorphine to improve HIV care engagement and outcomes; study completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-22Clinical Trial Update: Pharmacokinetic Study of Cabotegravir Long-acting in Healthy Adult Volunteers [Phase 1]
Phase 1 pharmacokinetic study of long-acting cabotegravir in healthy adults completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-06-22Clinical Trial Update: Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen [Phase 4]
Phase 4 trial evaluating the effect of atorvastatin on aging-related complications in HIV-infected patients over 45 on protease inhibitor th…