HIV Infection
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CLINICAL_TRIALS trial_result · 2024-01-25Clinical Trial Update: Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating interferon-gamma as part of complex treatment for patients with HIV and tuberculosis has completed, wi…
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya [NA]
Clinical trial update from Kenya evaluating an agricultural intervention to improve food security and HIV health outcomes; the study is comp…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Developing Online Interventions to Reduce Stigma-Related Stress, Sexual Health, and HIV Risk Among Young Chinese MSM [NA]
Clinical trial completed that developed online interventions aimed at reducing stigma-related stress, sexual health issues, and HIV risk amo…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Pharmacokinetics and Safety of SAR441236 [Phase 1]
Phase 1 pharmacokinetics and safety update for SAR441236 in HIV-1 infection; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Allogeneic Adoptive Immune Therapy for Advanced AIDS Patients [Phase 2]
Phase 2 clinical trial update for allogeneic adoptive immune therapy in advanced AIDS patients.
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: Single-cell CBD Biomarkers of Inflammation Reduction in People Living With HIV [Phase 4]
Phase 4 trial investigating single-cell CBD biomarkers of inflammation reduction in people living with HIV has been completed with results p…
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: Mhealth for PrEP Adherence by Young Adult MSM, Phase 2 [NA]
Phase 2 clinical trial update on mobile health support for PrEP adherence in young adult men who have sex with men; study completed with res…
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection [Phase 4]
Phase 4 trial update evaluating switching from TDF-based ART regimens to B/F/TAF in virally suppressed adults with HIV-1 infection.
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Strategic Timing of Antiretroviral Treatment [Phase 4]
A Phase 4 clinical trial evaluating the strategic timing of antiretroviral therapy in HIV infection has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: The Influence of Concurrent Oral Calcium Carbonate Supplementation on Steady State Pharmacokinetics of Oral Raltegravir. [Phase 4]
Phase 4 trial update evaluating whether concurrent oral calcium carbonate affects steady-state pharmacokinetics of oral raltegravir in HIV p…
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Islatravir and Methadone Pharmacokinetics (MK-8591-029) [Phase 1]
Phase 1 pharmacokinetic study evaluating islatravir (MK-8591) in individuals taking methadone; results posted.
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Doravirine/Islatravir (DOR/ISL) in Heavily Treatment-Experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019) [Phase 3]
Phase 3 trial MK-8591A-019 evaluating the Doravirine/Islatravir combination in heavily treatment-experienced HIV-1 infection reported result…
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Postpartum Pre-exposure Prophylaxis (PrEP) Study to Evaluate an Adherence Promotion Package for Postpartum Women on PrEP [NA]
A completed clinical trial evaluating an adherence promotion package for postpartum women on PrEP (pre-exposure prophylaxis) for HIV infecti…
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Evaluation of Secondary Distribution of HIV Self-screening Tests by Women With HIV [NA]
A completed clinical trial evaluating secondary distribution of HIV self-screening tests by women with HIV; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions [Phase 4]
A Phase 4 pharmacokinetic study evaluating nevirapine levels in HIV-infected patients with hepatic impairment.
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: Dual Therapy With Boosted Darunavir + Dolutegravir [Phase 3]
Phase 3 clinical trial update on boosted darunavir plus dolutegravir for HIV infection has completed.
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men [Phase 2, Phase 3]
Phase 2/3 clinical trial comparing injectable cabotegravir to TDF/FTC for HIV pre-exposure prophylaxis in HIV-uninfected men and transgender…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Study of Doravirine/Islatravir (DOR/ISL 100 mg/0.75 mg) to Evaluate the Antiretroviral Activity, Safety, and Tolerability in Treatment-Naïve Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-020) [Phase 3]
Phase 3 study MK-8591A-020 assessing Doravirine/Islatravir for treatment-naïve HIV-1 infection completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Study of Doravirine/Islatravir (DOR/ISL 100 mg/0.75 mg) to Evaluate the Antiretroviral Activity, Safety, and Tolerability in Treatment-Naïve Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-020) [Phase 3]
Phase 3 trial evaluating doravirine/islatravir combination in treatment-naïve HIV-1 patients; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Exercise Training to Improve Brain Health in Older HIV+ Individuals [NA]
A terminated clinical trial investigated exercise training as a strategy to improve brain health in older individuals living with HIV; resul…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: A Study to Evaluate the Antiviral Effect, Safety and Tolerability of GSK3810109A in Viremic Human Immunodeficiency Virus (HIV)-1 Infected Adults [Phase 2]
Phase 2 trial evaluating antiviral effect, safety and tolerability of GSK3810109A in viremic HIV-1 infected adults has completed with result…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults [Phase 2]
A Phase 2 dose-range finding trial in treatment-naive adults with HIV-1 has been terminated, and the study results have been posted.
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Tambua Mapema Plus - to Discover HIV Infection Early and Prevent Onward Transmission [NA]
A completed clinical trial update for Tambua Mapema Plus aimed at early HIV infection detection and prevention of onward transmission; resul…
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: A Digital Intervention for HIV Prevention in Black Adolescent Girls [NA]
Clinical trial completed evaluating a digital intervention for HIV prevention in Black adolescent girls; results posted.
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial) [NA]
An implementation trial compared different delivery methods for the 3HP regimen (isoniazid–rifapentine) to prevent tuberculosis in individua…