HIV Infection
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: ART First-line Treatment Durability in Russia
A completed clinical trial update reports on first-line ART durability in people with HIV-1 infection in Russia, with results posted in 2024…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Feasibility of the Mindfulness-Based Stress Reduction Intervention for Black Women Living With HIV [NA]
A completed feasibility trial assessed mindfulness-based stress reduction for Black women living with HIV; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Effect of N-803 on B Cell Follicles in Antiretroviral Treated HIV Disease [Phase 1]
Phase 1 trial examining the effect of N-803 on B cell follicles in antiretroviral-treated HIV disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: Randomized Pilot Study of a mHealth App for Ambivalent Smokers Living With HIV [NA]
A randomized pilot study evaluated a mobile health app for ambivalent smokers living with HIV; results posted after completion.
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: COVID-19 CoronaVac in Patients With Autoimmune Rheumatic Diseases and HIV/AIDS [Phase 4]
Phase 4 clinical trial update evaluating COVID-19 CoronaVac in patients with autoimmune rheumatic diseases and HIV/AIDS; completed.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Evaluation of Pre-Exposure Prophylaxis (PrEP) in Pregnant and Breastfeeding Women
This clinical trial update announces completion and results posting for a study evaluating pre-exposure prophylaxis (PrEP) in pregnant and b…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: A Relative Bioavailability and Food-Effect Study of the Fixed Dose Combination of GSK3640254 and Dolutegravir (DTG) in Healthy Participants [Phase 1]
Phase 1 trial assessing relative bioavailability and food effects of a fixed-dose combination of GSK3640254 and dolutegravir in healthy part…
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Bictegravir/Emtricitabine/Tenofovir Alafenide Plus Doravirine [Phase 4]
Phase 4 clinical trial of a bictegravir/emtricitabine/tenofovir alafenamide plus doravirine regimen for HIV-1 infection has completed with r…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy [Phase 1, Phase 2]
A phase 1/2 trial evaluated strategies to reduce the residual reservoir of HIV-1 infected cells in patients on antiretroviral therapy; the s…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Switching From Protease Inhibitor/Ritonavir to Generic Single Tablet Regimen of Tenofovir Alafenamide/Emtricitibine/Dolutegravir [Phase 3]
A Phase 3 trial assessing switch from protease inhibitor/ritonavir to a generic single-tablet regimen of tenofovir alafenamide/emtricitabine…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: 2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial [Phase 4]
A Phase 4 randomized trial comparing 2DR versus 3DR in people with HIV-1 infection is currently recruiting
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Adherence to HIV Treatment Postpartum: The Implications of Transitions Among Women Living With HIV in South Africa [NA]
Clinical trial completed; study examined adherence to HIV treatment postpartum among women living with HIV in South Africa, with results pos…
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France. [Phase 3]
Phase 3 trial update on long-acting injectable cabotegravir for HIV PrEP in men who have sex with men in France; status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: Efficacy of Dolutegravir Plus Lamivudine in HIV-1-infected Treatment-naïve Adults Without a Baseline Genotyping Test [Phase 4]
Phase 4 trial update evaluating efficacy of dolutegravir plus lamivudine in treatment-naïve HIV-1–infected adults without baseline genotypin…
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: Call for Life Youth ART Adherence Study [NA]
Clinical trial update for an ART adherence study among youth; study completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission [NA]
A completed clinical trial (TechStep) evaluating a technology-based stepped care approach for reducing HIV risk transmission in transgender …
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: Interrupting HIV and TB Stigma in the Household in Uganda [NA]
A completed clinical trial in Uganda explored interventions to interrupt HIV and tuberculosis stigma within households, with results posted …
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection [Phase 1]
Phase 1 trial evaluating PD-1 inhibition to determine the central nervous system reservoir of HIV infection; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: A Study of a Nucleoside Sparing Regimen in HIV-1 Infected Patients With Detectable Viremia [Phase 2]
Phase 2 clinical trial update for a nucleoside-sparing regimen in HIV-1 infected patients with detectable viremia.
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed, HIV-1 Infected Patients (Be-OnE) [Phase 3]
Phase 3 trial Be-OnE evaluating switching virologically suppressed HIV-1 patients from dolutegravir-based regimens to E/C/F/TAF; study termi…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Addressing Drug Use Stigma in Human Immunodeficiency Virus (HIV) Care and Treatment Clinics in Tanzania [NA]
A completed clinical trial in Tanzania evaluated approaches to reduce drug use stigma in HIV treatment clinics, with results publicly posted…
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women [NA]
A completed clinical trial comparing two intrauterine devices (IUDs) conducted among HIV-positive women in Cape Town; results posted in 2024…
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Optimizing Reversal of HIV Latency With Combination Therapy [Phase 1, Phase 2]
Early-phase clinical trial update exploring combination therapy to optimize reversal of HIV latency.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB [Phase 4]
Phase 4 trial update evaluating the pharmacokinetics of twice-daily or once-daily DTG (50 mg) in children with HIV and tuberculosis.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Task-shifted Adaptation of the WHO-PEN Intervention to Address Cardio-metabolic Complications in People Living With HIV in Zambia [NA]
A completed clinical trial evaluating task-shifted adaptations of the WHO-PEN intervention to address cardio-metabolic complications in peop…