HIV Infection
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Descriptive Analysis of Changes in Hepatitis B Markers in People Living With HIV on Injectable Therapy.
This clinical trial update provides a descriptive analysis of changes in Hepatitis B markers in people living with HIV who are on injectable…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study) [Phase 2]
Phase 2 study of semaglutide for non-alcoholic fatty liver disease in HIV infection completed, with results posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Impact of Probiotics in HIV-positive Patients With Neurocognitive Disorders [NA]
A completed clinical trial evaluated the impact of probiotics in HIV-positive patients with HIV-associated neurocognitive disorder.
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents [Phase 1, Phase 2]
The MOCHA study reports Phase 1/2 results for HIV-infected children and adolescents treated with oral and long-acting injectable cabotegravi…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Impact of COVID-19 on Provision and Uptake of Prevention of Mother-to-child Transmission of HIV Services in Zimbabwe
A completed clinical trial evaluating how COVID-19 affected the provision and uptake of HIV prevention of mother-to-child transmission servi…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Project WERK (Wellness Encouragement Respect Kinship) [NA]
A University of Chicago-sponsored clinical trial (Project WERK) evaluating HIV prevention has completed.
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs [Phase 4]
A Phase 4 trial evaluating Triumeq as an integrase single-tablet regimen for people with HIV who inject drugs was terminated.
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: BFTAF Elderly Switch Study [Phase 4]
A Phase 4 clinical trial conducted by the University of Nairobi evaluating an elderly-switch strategy for people with HIV-1 infection has co…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment [Phase 2, Phase 3]
This completed Phase 2/3 trial evaluated the effect of combining aerobic training with Ginkgo biloba on lipid levels in HIV-positive patient…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Cohort for Evaluation of Open-label PrEP Use and PreP Preferences Among African Women
A completed cohort study evaluating open-label PrEP use and PrEP preferences among African women to inform HIV prevention strategies.
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ [NA]
A completed clinical trial in Zambia assessing adolescent HIV-related and sexual health outcomes has posted results as part of efforts to re…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Impact of Raltegravir Intensification on HIV-1-infected Subjects With Complete Viral Suppression Under Monotherapy With Protease Inhibitors [Phase 3]
Phase 3 trial evaluating the impact of adding raltegravir to protease inhibitor monotherapy in HIV-1 infected individuals with sustained vir…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: SSRI Effects on Depression and Immunity in HIV/AIDS [Phase 4]
Phase 4 trial evaluating SSRIs' effects on depression and immune markers in people with HIV/AIDS. Results were posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: A Phase I, Randomized, Double-Blind, Placebo-Controlled Safety, Tolerability and Immunogenicity Study of Candidate HIV-1 Vaccines ChAdOx1.HTI and MVA.HTI With Recombinant HIV-1 Envelope Protein ConM SOSIP.v7 gp140 Vaccine, Adjuvanted With MPLA Liposomes in ART-Suppressed HIV-1 Positive Individuals [Phase 1]
Phase 1 randomized, double-blind, placebo-controlled study evaluating safety, tolerability, and immunogenicity of HIV-1 vaccines ChAdOx1.HTI…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Safety and Immunogenicity of ChAdV63.HIVconsv and MVA.HIVconsv Candidate HIV-1 Vaccines in Recently HIV-1 Infected Individuals [Phase 1]
Phase 1 trial assessing safety and immunogenicity of two HIV vaccine candidates, ChAdV63.HIVconsv and MVA.HIVconsv, in individuals recently …
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Study to Evaluate the Safety and Effect of HIVconsv Vaccines in Combination With Histone Deacetylase Inhibitor Romidepsin on the Viral Rebound Kinetic After Treatment Interruption in Early Treated HIV-1 Infected Individuals [Phase 1]
A Phase 1 trial studied the safety and potential impact of combining the HIVconsv vaccine with romidepsin on viral rebound after treatment i…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV
A completed clinical trial evaluated tailoring shared decision making for lung cancer screening among people living with HIV, with results p…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed [Phase 2]
Phase 2 study evaluating switching to rilpivirine-containing regimens in virologically suppressed HIV-1-infected children aged 2 to <12 year…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Reducing Post-Hospital Mortality in HIV-infected Adults in Tanzania [NA]
A clinical trial in Tanzania evaluating approaches to reduce post-hospital mortality among HIV-infected adults has completed and posted resu…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Maraviroc Efficacy for Hepatitis C [Phase 4]
Phase 4 clinical trial update assessing maraviroc for hepatitis C in HIV-infected individuals; the study has completed and results were post…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Self-management of HIV Among Adolescents [NA]
This update reports the completion of a clinical trial evaluating self-management strategies for HIV among adolescents.
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) [Phase 4]
This Phase 4 trial (ReSTART) tested rapid reinitiation of Symtuza in HIV-1-infected, treatment-experienced patients off therapy. The study h…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: A Study of CL-197 Capsules in Healthy Participants [Phase 1]
Phase 1 trial evaluating the safety and pharmacokinetics of CL-197 capsules in healthy participants, with HIV-1 listed as the condition.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Clinical Effectiveness-Implementation Hybrid Type 2 Study on Home-Delivered Cabenuva for People Living With HIV Who Are Not Retained in Care
An ongoing hybrid effectiveness-implementation study is evaluating home-delivered Cabenuva for people living with HIV who are not retained i…
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: Immunologic Response to Kansui in Treated HIV+ Individuals: a Dose Escalation Study [Phase 1]
Phase 1 dose-escalation study evaluating immunologic response to Kansui in treated HIV+ individuals; the study is terminated with results po…