HIV Infection
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Using Electronic Medical Record Data to Improve HIV Primary Care [NA]
A completed clinical trial from Unity Health Toronto evaluated the use of electronic medical record data to improve HIV primary care. The st…
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Early Anti-Retroviral Treatment in HIV- Infected Children
The document reports the completion of a clinical trial evaluating early initiation of antiretroviral therapy in HIV-infected children.
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Open-Label Multi-Centre Randomised Switch Study to Evaluate Virological Efficacy Over 96Weeks Of 2-Drug Therapy With Dolutegravir(DTG)/Rilpivirine(RPV) Fixed Dose Combination(FDC) in Antiretroviral Treatment-Experienced HIV-1 Infected Subjects Virologically Suppressed With NNRTI Mutation K103N [Phase 3]
Open-label Phase 3 switch study evaluating the virological efficacy of a dolutegravir/rilpivirine fixed-dose combination in ART-experienced,…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Defining the Potency of DTG/3TC for Suppressed HIV Patients in Real-life: the DUALING Study
A clinical trial update focusing on the potency of the DTG/3TC fixed-dose combination for people with suppressed HIV in real-world settings …
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Crowdsourcing to Reduce HIV Stigma Among Adolescents and Young Adults in Kazakhstan [NA]
Completed clinical trial in Kazakhstan evaluating crowdsourcing to reduce HIV stigma among adolescents and young adults and to improve HIV t…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: NOLA GEM: Feasibility and Acceptability of an MHealth Intervention for Violence-affected PLWH [NA]
This completed clinical trial evaluates the feasibility and acceptability of a mobile health intervention for violence-affected people livin…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Adherence Interventions for HIV Youth Via Text & Cell Phone - Sequential Multiple Assignment Randomized Trial (SMART) [NA]
Update on a sequential multiple assignment randomized trial evaluating text messaging and cell phone–based adherence interventions for HIV-i…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult Participants [Phase 1]
Phase 1 trial evaluating safety, tolerability, pharmacokinetics, and antiviral activity of HIV broadly neutralizing antibodies PGT121.414.LS…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Biomarkers to Predict Time to Plasma HIV RNA Rebound
A completed clinical trial evaluating biomarkers that predict the time to HIV-1 RNA rebound in plasma.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Observational PIC Destination Cohort
This update announces a recruiting observational cohort study (PIC Destination) related to HIV infection.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: E-Health for Zero Infections - Facilitating Access to and Use of HIV Pre-Exposure Prophylaxis (PrEP) in the Netherlands [NA]
This clinical trial update reports the completion of a Netherlands-based study on e-Health strategies to facilitate access to and use of HIV…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Ending Transmission of HIV, HCV, and STDs and Overdose in Rural Communities of People Who Inject Drugs (ETHIC) [NA]
The ETHIC trial, studying strategies to end HIV and Hepatitis C transmission and reduce overdose risk among rural people who inject drugs, h…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Connecting Resources for Urban Sexual Health [NA]
This clinical trial update notes the completion of the NCT02183909 study on connecting resources for urban sexual health, with results poste…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024) [Phase 3]
Phase 3 trial MK-8591-024 evaluating once-monthly oral islatravir for HIV PrEP in at-risk men and transgender women has been terminated, wit…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Tobacco Cessation Tailored to Patients Living With HIV (PLWH) in Brazil [NA]
A completed clinical trial in Brazil tested a tobacco cessation intervention tailored for people living with HIV, and results have been post…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: HIV-Related Stigma Intervention for Malaysian Clinicians [NA]
A completed clinical trial evaluating an intervention to reduce HIV-related stigma among Malaysian clinicians, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers [Phase 1]
Phase 1 results report on the metabolic and endocrine effects of Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) on insulin sensi…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants [Phase 1]
A Phase 1 study evaluated the potential drug-drug interaction between VH4524184 and the oral contraceptive Loestrin in healthy adult female …
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Screening for HPV and Cervical Cancer in Young Women With Perinatally Acquired HIV
Completed clinical trial update on screening for human papillomavirus and cervical cancer in young women with perinatally acquired HIV; resu…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: The Effect on Lipid Profile of Switching to Delstrigo in HIV Positive Patients [Phase 4]
This Phase 4 study evaluates the effect on lipid profile when HIV-positive patients switch to Delstrigo. The trial was terminated.
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: To Reach Unrestricted Services for Transgender Women [NA]
The document notes the completion of a clinical trial examining unrestricted healthcare services for transgender women, including considerat…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Tajik Migrant Health Education Study [NA]
The Tajik Migrant Health Education Study has completed and posted results. It investigated health education strategies to address HIV and He…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care
The Instacare study reports results from rapid ART initiation among people with HIV who are out of care; the trial status is completed.
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults [Phase 1]
This Phase 1 trial update reports completion of a study evaluating the safety and immunogenicity of the recombinant HIV-1 BG505 SOSIP.GT1.1 …
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels [Phase 1]
Phase 1 drug-drug interaction study of Vesatolimod in adults with HIV infection was terminated and results have been posted.