HIV Infection
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: A Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding a Native-like HIV Env Trimer and Interleukin-12 (INO-6160), Alone or in a Prime-boost Regimen With 3M-052-AF + Alum Adjuvanted VRC HIV Env Trimer 4571 in Adult Participants Without HIV [Phase 1]
Phase 1 trial assessing safety and immunogenicity of INO-6160 (DNA vaccine encoding native-like HIV Env trimer and interleukin-12) given alo…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Behavioral Activation, Nutrition, and Activity Intervention [NA]
A completed clinical trial evaluated a Behavioral Activation, Nutrition, and Activity Intervention for people with HIV.
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 1 [NA]
A completed pilot clinical trial (HARP Pilot 1) at Yale evaluating polypharmacy in people with HIV and alcohol use disorder; results have be…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men [Phase 4]
Clinical trial update announcing the completion of a Phase 4 study evaluating the DOT Diary mobile app for adherence to HIV pre-exposure pro…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Implementation and Effectiveness of a Psychosocial Intervention Among Registered People Living With HIV(HIV Patients) at Pakistan Institute of Medical Sciences (PIMS) Islamabad Pakistan. [NA]
Clinical trial completed at Pakistan Institute of Medical Sciences assessing the implementation and effectiveness of a psychosocial interven…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide [Phase 4]
Phase 4 trial evaluating doravirine for obese adults on integrase inhibitors and tenofovir alafenamide has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening [NA]
A completed clinical trial from the University of Michigan tested a motivational interviewing-based telehealth intervention to promote scree…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: East Africa Point of Care Viral Load Study [NA]
Clinical trial update for the East Africa Point of Care Viral Load study reports completion of the trial evaluating point-of-care HIV viral …
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1 [Phase 2]
Phase 2 proof-of-concept study of VH4524184 in treatment-naïve adults with HIV-1 has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: PrEP Readiness Interventions for Supporting Motivation [NA]
A completed clinical trial evaluating PrEP readiness interventions designed to support motivation for HIV pre-exposure prophylaxis; results …
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)
This completed clinical trial analyzed cerebrospinal fluid in patients with cerebral toxoplasmosis to characterize CSF findings; the study a…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected Adults [Phase 1]
Phase 1 study evaluating safety and immunogenicity of HIV-1 BG505 SOSIP.664 gp140 vaccine with TLR agonist and/or Alum adjuvants in healthy …
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression [Phase 1]
This update reports the completion of a Phase 1 study evaluating the acceptability and feasibility of a family-based prevention program to r…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Electronic SBI(RT) for MSM in Argentina [NA]
The clinical trial evaluating electronic SBI (e-SBI) for men who have sex with men in Argentina has been terminated.
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth [NA]
The study completed and posted results evaluating a nurse case management intervention to prevent HIV and improve HIV care among homeless yo…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Can Resistance Enhance Selection of Treatment? (CREST) [NA]
The CREST trial (NCT00262717) examining whether resistance can enhance selection of HIV treatment has completed. The update provides status …
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old
A completed clinical trial evaluating cognitive impairment in older adults with HIV infection. The study status is completed, with no detail…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Integrated Prevention of HIV Risk and Intimate Partner Violence Among Adolescents in South Africa [NA]
A completed clinical trial in South Africa evaluated integrated strategies to prevent HIV risk and intimate partner violence among adolescen…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: 1:1 Comparison of the Pocket Colposcope in Kenya [NA]
A completed clinical trial in Kenya comparing the Pocket Colposcope to standard assessment, sponsored by Duke University, with results poste…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Piloting Eye Movement Desensitization and Reprocessing (EMDR) Therapy in People Living With HIV and Trauma [NA]
A clinical trial evaluating the use of EMDR therapy to address trauma in people living with HIV has completed.
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Supporting Young Women's Reproductive Health by Harnessing Prosociality Among Drug Shopkeepers [NA]
This clinical trial evaluated whether leveraging drug shopkeepers’ prosocial behavior could improve reproductive health outcomes for young w…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Alignment of PrEP Use With HIV Risk in Young Women and Men [Phase 4]
Phase 4 study examining alignment of pre-exposure prophylaxis (PrEP) use with HIV risk among young women and men; the trial is completed and…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Feminizing Hormone Therapy and the Rectal Mucosa Immune Environment in Transgender Women
A completed clinical trial evaluating feminizing hormone therapy and its effects on the rectal mucosal immune environment in transgender wom…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Piloting a Smartphone App to Improve Treatment Adherence Among South African Adolescents Living With HIV [NA]
This update describes the completion of a pilot trial testing a smartphone app intended to improve treatment adherence in South African adol…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Zinc Effect on Inflammation and Cardiovascular Risk in HIV [EARLY_Phase 1]
Early-phase 1 trial evaluating zinc supplementation for its effects on inflammation and cardiovascular risk in HIV-associated inflammation, …