HIV Infection
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS [Phase 1]
A Phase 1 trial evaluating the safety and preliminary effectiveness of combining clarithromycin with zidovudine or didanosine for Mycobacter…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection
This clinical trial compares HIV-infected patients with and without AIDS-related opportunistic infections, examining outcomes related to cyt…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: A Randomized Study of Activity, Safety, and Tolerance of Oral Ro 24-7429 (Tat Antagonist) in Patients With HIV Infection [Phase 1]
Phase 1 randomized study evaluating activity, safety, and tolerance of the oral Tat antagonist Ro 24-7429 in HIV infection.
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CLINICAL_TRIALS trial_result · 2008-08-01Clinical Trial Update: A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C Infection
This clinical trial update indicates a study evaluating anti-HIV drugs in HIV-positive patients with Hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2008-08-01Clinical Trial Update: Setting up a Blood Bank for Gene Therapy in HIV-Infected Infants
This update reports termination of a clinical trial (NCT00000917) sponsored by NIAID that aimed to set up a blood bank to support gene thera…
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CLINICAL_TRIALS trial_result · 2008-07-31Clinical Trial Update: Daily Nevirapine to Prevent Mother to Infant Transmission of HIV [Phase 3]
Phase 3 trial evaluating daily nevirapine to prevent mother-to-child transmission of HIV has completed.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: Treatment of Hepatitis C in Hemophilic Patients With HIV [Phase 2]
A completed Phase 2 clinical trial evaluated treatment for Hepatitis C in patients with HIV infection and hemophilia.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive Patients
A completed clinical trial assessed the effects of stopping preventive therapy for Mycobacterium avium complex infection in HIV-positive pat…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection [Phase 1]
A Phase 1 clinical trial evaluates the safety and effectiveness of a regimen combining Interleukin-2 with Zidovudine and Thymosin in HIV-inf…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: An Open-Label, Staggered Rising Dose Cohort Study Assessing the Pharmacokinetics, Safety, and Tolerance of BI-RG-587 in Combination With Zidovudine in Patients With HIV Infection (CD4+ Cell Count < 400/mm3) [Phase 1]
This Phase 1 open-label study evaluated the pharmacokinetics, safety, and tolerability of BI-RG-587 in combination with zidovudine in HIV-in…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: The Effects of Anti-HIV Drugs on the HIV Virus in HIV-Infected Patients
This completed clinical trial evaluated how anti-HIV drugs affect HIV viral levels in HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: Effectiveness of Adding Remune to Your Current Anti-HIV Drug Combination [Phase 1]
This Phase 1 trial evaluated adding Remune to participants' existing antiretroviral therapy for HIV infection; the study was terminated.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: Safety and Tolerability of the Vaginal Gel PRO 2000/5 [Phase 1]
This document reports a Phase 1 clinical trial update on the safety and tolerability of the vaginal gel PRO 2000/5 for HIV infection.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study to Evaluate the Effects of Stopping Maintenance Therapy for Cytomegalovirus (CMV) Retinitis After Effective Anti-HIV Therapy
A completed clinical trial assessing whether stopping maintenance therapy for Cytomegalovirus Retinitis is safe after effective anti-HIV the…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Pharmacokinetic Study of L-697,661 Alone and in Combination With Zidovudine [Phase 1]
A phase 1 pharmacokinetic study evaluated L-697,661 alone and in combination with zidovudine in HIV infections. The study status is complete…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Blood Test to Look at Cells of the Immune System in Healthy Children
The NIAID-sponsored trial evaluating a blood test to examine immune cells in children has completed, with HIV infection and HIV seronegativi…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study to Demonstrate That Anti-HIV Drug Therapy Can be Stopped Without Causing Viral Resistance, and to Characterize Drug Elimination From the Body [Phase 2]
A Phase 2 clinical trial completed to determine whether stopping anti-HIV therapy can be done without causing viral resistance and to charac…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: The Effects of Valproic Acid on Zidovudine Glucuronidation and Pharmacokinetics in HIV-Infected Patients. [Phase 1]
Phase 1 study evaluating how valproic acid affects zidovudine glucuronidation and pharmacokinetics in HIV-infected individuals.
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: Comparing Single Photon Emission Computed Tomography (SPECT) and Liver Biopsy to Evaluate the Liver in Patients With HIV and Hepatitis C Virus
A completed clinical trial comparing SPECT imaging to liver biopsy for evaluating liver health in patients with HIV infection and Hepatitis …
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study of Immune System Activity in Healthy Adults
The study, conducted by the National Institute of Allergy and Infectious Diseases, completed a trial evaluating immune system activity in he…
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CLINICAL_TRIALS trial_result · 2008-07-29Clinical Trial Update: Ritonavir-Boosted GS-9137 vs. Ritonavir-Boosted Protease Inhibitor(s) in Combination With Background ART. [Phase 2]
Phase 2 trial comparing ritonavir-boosted GS-9137 (elvitegravir) against ritonavir-boosted protease inhibitors, both with background ART, in…
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CLINICAL_TRIALS trial_result · 2008-07-29Clinical Trial Update: Evaluation of the Changes in HIV-1 Burden in Peripheral Blood and Lymphoid Tissue Following Zidovudine ( AZT ) Treatment in HIV-1-Infected Patients With CD4+ Cells Between 100 and 500 Cells/mm3. [Phase 1]
This Phase 1 clinical trial evaluates how Zidovudine (AZT) treatment affects HIV-1 burden in blood and lymphoid tissue in HIV-1-infected pat…
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CLINICAL_TRIALS trial_result · 2008-07-29Clinical Trial Update: HIV Levels in Cerebrospinal Fluid and Brain Function in Patients Receiving Anti-HIV Drugs
A completed clinical trial investigated HIV levels in cerebrospinal fluid and their relationship to brain function in patients receiving ant…
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CLINICAL_TRIALS trial_result · 2008-07-15Clinical Trial Update: A Study of Zidovudine in Infants Exposed to the HIV Before or Soon After Birth [Phase 1]
Phase 1 study evaluating the safety and pharmacokinetics of zidovudine in infants exposed to HIV before or shortly after birth.
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CLINICAL_TRIALS trial_result · 2008-07-10Clinical Trial Update: Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected Patients [Phase 3]
A Phase 3 trial compares a simplified two-drug Kaletra regimen to the standard three-drug Kaletra regimen in treatment-naïve HIV patients; t…