HIV Infection
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: TMC125-C223: TMC125 in HIV-1 Infected Subjects [Phase 2]
This document reports the completion of a Phase 2 study evaluating TMC125 (dapivirine) in HIV-1 infected subjects (TMC125-C223).
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: Innovation-TiFP4-C101: A Study to Evaluate the Pharmacokinetics of TMC114 and TMC41629 After a Single Oral Dose of 2 Controlled-release Coformulations as Compared to an Immediate-release Coformulation of TMC114/TMC41629 [Phase 1]
Phase 1 pharmacokinetic study comparing controlled-release formulations of TMC114 (darunavir) and TMC41629 to an immediate-release formulati…
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients [Phase 2]
Phase II randomized, placebo-controlled, dose-escalation trial of TMC125 (dapivirine) in HIV-1 infected patients has completed.
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function. [Phase 1]
Phase 1 PK and safety study assessing rilpivirine (TMC278) in HIV patients with mild-to-moderate hepatic impairment; focuses on pharmacokine…
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: TMC278-TiDP6-C121: Drug-drug Interaction Trial to Investigate the Potential Interaction Between TMC278 25 mg Daily and Methadone, at Steady State. [Phase 1]
Phase 1 trial evaluating potential drug-drug interaction between rilpivirine (TMC278) 25 mg daily and methadone at steady state in HIV-infec…
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CLINICAL_TRIALS trial_result · 2010-04-26Clinical Trial Update: Long-Term Effects of HAART in Youth With Stronger Immune Systems Versus Youth With Weaker Immune Systems
A completed study comparing long-term effects of HAART in youths with stronger immune systems versus youths with weaker immune systems.
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CLINICAL_TRIALS trial_result · 2010-04-23Clinical Trial Update: Breastfeeding, Antiretroviral, and Nutrition Study [Phase 3]
Phase 3 clinical trial sponsored by the CDC investigating breastfeeding, antiretroviral therapy, and nutrition in HIV infection has complete…
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CLINICAL_TRIALS trial_result · 2010-04-21Clinical Trial Update: Acupressure to Treat Nausea and Vomiting in HIV/AIDS Patients [Phase 1]
Phase 1 trial evaluating acupressure to treat nausea and vomiting in HIV/AIDS patients has completed.
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CLINICAL_TRIALS trial_result · 2010-04-14Clinical Trial Update: Study of Home-Based Resistance and Strength Training in HIV-Infected Women [NA]
This ClinicalTrials.gov entry reports a completed study evaluating a home-based resistance and strength training program in HIV-infected wom…
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CLINICAL_TRIALS trial_result · 2010-04-12Clinical Trial Update: Safety and Efficacy of an Investigational Drug in Human Immunodeficiency Virus (HIV)-Infected Patients Failing Current Antiretroviral Therapies (0518-005)(COMPLETED) [Phase 2]
Phase 2 trial assessing safety and efficacy of an investigational HIV drug in patients failing current antiretroviral therapy, with results …
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CLINICAL_TRIALS trial_result · 2010-04-12Clinical Trial Update: A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment). [Phase 2]
This Phase 2 pharmacokinetic study evaluated how etravirine (TMC125) plus tenofovir/emtricitabine, with or without boosted darunavir/ritonav…
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CLINICAL_TRIALS trial_result · 2010-03-31Clinical Trial Update: Switching From PI to RALtegravir in HIV Stable Patients [Phase 3]
Phase 3 trial updated results on switching from protease inhibitors to raltegravir in HIV-infected patients stable on therapy; study has com…
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CLINICAL_TRIALS trial_result · 2010-03-31Clinical Trial Update: Atazanavir or Lopinavir in HIV Post-exposure Prophylaxis [Phase 4]
This document reports the completion status of a Phase 4 trial evaluating Atazanavir or Lopinavir for HIV post-exposure prophylaxis.
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CLINICAL_TRIALS trial_result · 2010-03-31Clinical Trial Update: Integrase Resistance Analysis in HIV Patients Who Interrupted Raltegravir Due to Incomplete Viral Suppression [NA]
This clinical trial update analyzes integrase resistance in HIV-infected patients who interrupted raltegravir due to incomplete viral suppre…
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CLINICAL_TRIALS trial_result · 2010-03-29Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of an Investigational Drug in HIV Infected Patients (0518-004)(COMPLETED) [Phase 2]
The document reports the completed Phase 2 study assessing the safety and efficacy of an investigational drug in HIV-infected patients, with…
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CLINICAL_TRIALS trial_result · 2010-03-29Clinical Trial Update: Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings [NA]
This document provides an update on a completed clinical trial evaluating the effectiveness of directly observed therapy for combined HIV an…
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CLINICAL_TRIALS trial_result · 2010-03-25Clinical Trial Update: Observing Patients With Early HIV Infection
A completed clinical trial observing patients with early HIV infection to study disease progression and early treatment effects.
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CLINICAL_TRIALS trial_result · 2010-03-19Clinical Trial Update: Multicenter Pilot Study To Define The Marker As An Alternate For Tropism Assay [Phase 1]
Phase 1 multicenter pilot study to evaluate a biomarker as an alternative tropism assay for HIV infections; the trial was terminated with re…
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CLINICAL_TRIALS trial_result · 2010-03-19Clinical Trial Update: Comparison of Concentration-time Course of Plasma and Intracellular Raltegravir in Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetic study comparing plasma and intracellular concentrations of raltegravir in healthy volunteers.
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CLINICAL_TRIALS trial_result · 2010-03-19Clinical Trial Update: Reducing HIV Risk Among Mexican Youth [NA]
A University of Michigan-led clinical trial studying strategies to reduce HIV risk among Mexican youth has completed.
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CLINICAL_TRIALS trial_result · 2010-03-15Clinical Trial Update: Androgen Effects in HIV-infected Women [NA]
This clinical trial update reports results from a completed study examining androgen effects in HIV-infected women.
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CLINICAL_TRIALS trial_result · 2010-03-11Clinical Trial Update: Proyecto SOL: A Risk Reduction Intervention for Hispanic Men Who Have Sex With Men (MSM) [NA]
This entry notes the completion of Proyecto SOL, a risk-reduction intervention study for Hispanic men who have sex with men aimed at reducin…
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CLINICAL_TRIALS trial_result · 2010-03-09Clinical Trial Update: No Excuses/Sin Buscar Excusas Intervention to Reduce Latino Men's HIV Risks [Phase 2, Phase 3]
The trial update notes completion of Phase 2 and Phase 3 studies for a behavioral intervention aimed at reducing HIV risk in Latino men.
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CLINICAL_TRIALS trial_result · 2010-03-05Clinical Trial Update: Study of Boosted Atazanavir (ATV) Versus Non-boosted ATV in Naive Patients [Phase 4]
This Phase 4 trial compared boosted atazanavir with ritonavir versus non-boosted atazanavir in ART-naive HIV patients and has completed.
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CLINICAL_TRIALS trial_result · 2010-03-03Clinical Trial Update: Metabolic Effects of Switching Kaletra to Boosted Reyataz [NA]
Clinical trial evaluating metabolic effects of switching from Kaletra (lopinavir/ritonavir) to boosted Reyataz (atazanavir) in HIV patients;…