HIV Infection
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CLINICAL_TRIALS trial_result · 2011-12-16Clinical Trial Update: Immunogenicity and Tolerance of Two Strategies of Anti-HAV Vaccination in HIV-infected Patients [Phase 3]
This Phase 3 trial update reports on the immunogenicity and tolerability of two strategies for Hepatitis A vaccination in HIV-infected patie…
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CLINICAL_TRIALS trial_result · 2011-12-16Clinical Trial Update: Usage of Acyclovir for Suppression of HIV-1 and HSV-2 Coinfected Persons in Cameroon [Phase 2, Phase 3]
The update summarizes results from Phase 2/3 trials examining acyclovir to suppress HIV-1 and HSV-2 coinfection in Cameroon.
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CLINICAL_TRIALS trial_result · 2011-12-14Clinical Trial Update: Evaluation of the Public Health Interest of Kaletra: Impact on Resistance to Antiretrovirals (ARVs)
A completed clinical trial evaluated Kaletra's impact on resistance to antiretrovirals in people with HIV infection.
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CLINICAL_TRIALS trial_result · 2011-12-14Clinical Trial Update: An Expanded Safety Study of Dapivirine Gel 4789 in Africa [Phase 1, Phase 2]
An expanded safety study of the dapivirine vaginal gel (4789) in Africa has completed Phase 1/2 trials to assess safety for HIV prevention.
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CLINICAL_TRIALS trial_result · 2011-12-05Clinical Trial Update: Once-daily Highly Active Antiretroviral Treatment Regimen Administration in HIV-1 Infected Children in Burkina Faso (ANRS 12103 BURKINAME) [Phase 2]
This update describes a Phase 2 clinical trial (ANRS 12103 BURKINAME) evaluating a once-daily highly active antiretroviral regimen in HIV-1 …
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CLINICAL_TRIALS trial_result · 2011-12-05Clinical Trial Update: Tenofovir/Emtricitabine for PMTCT in Africa and Asia (ANRS 12109 TEmAA) [Phase 2]
Phase 2 trial update of Tenofovir disoproxil fumarate/emtricitabine for preventing mother-to-child transmission of HIV in Africa and Asia. T…
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CLINICAL_TRIALS trial_result · 2011-12-02Clinical Trial Update: Laboratory Study of Licensed H1N1 Influenza Vaccines in HIV-1 Perinatally Infected Children and Youth
The document reports completion of a laboratory study evaluating licensed H1N1 influenza vaccines in HIV-1 perinatally infected children and…
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: A Pilot Study Of A Novel Treatment Regimen, Maraviroc + Ritonavir Boosted Atazanavir, In Treatment Naive HIV-Infected Patients [Phase 2]
A Phase 2 pilot trial evaluated a regimen of maraviroc plus ritonavir-boosted atazanavir in treatment-naive HIV-1 patients; the study is com…
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CLINICAL_TRIALS trial_result · 2011-11-22Clinical Trial Update: Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving Rifampin [Phase 3]
Phase 3 trial comparing efavirenz-based versus nevirapine-based antiretroviral therapy in HIV-infected patients receiving rifampin. The stud…
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CLINICAL_TRIALS trial_result · 2011-11-21Clinical Trial Update: ONCE - Only Nocturnal Combination Evaluation of Antiretroviral-Experienced HIV 1 Infected Subjects Switching to Atripla [Phase 4]
Phase 4 trial update of HIV-1 infected, antiretroviral-experienced subjects switching to Atripla (efavirenz/emtricitabine/tenofovir disoprox…
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CLINICAL_TRIALS trial_result · 2011-11-21Clinical Trial Update: ROCKET II - Randomized Open Label Switch for Cholesterol Elevation on Kivexa + Kaletra Evaluation Trial [Phase 4]
Phase 4 randomized open-label trial evaluating switching HIV-1 patients taking Kivexa plus Kaletra to address cholesterol elevations. The st…
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CLINICAL_TRIALS trial_result · 2011-11-17Clinical Trial Update: Appropriate Timing of HAART in Co-infected HIV/TB Patients [Phase 4]
This update covers a Phase 4 trial evaluating the optimal timing of HAART in patients co-infected with HIV and tuberculosis, which was termi…
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CLINICAL_TRIALS trial_result · 2011-11-11Clinical Trial Update: Effectiveness of an HIV Prevention Program That Targets the Inner Workings of High-risk Social Networks [Phase 2]
Phase 2 trial results indicate the HIV prevention program targeting high-risk social networks is effective in preventing HIV infections.
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CLINICAL_TRIALS trial_result · 2011-11-11Clinical Trial Update: Ritonavir-boosted Lopinavir Monotherapy [Phase 3]
Phase 3 trial evaluating ritonavir-boosted lopinavir monotherapy for HIV has completed.
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CLINICAL_TRIALS trial_result · 2011-11-08Clinical Trial Update: A Study To Assess GW433908 (Fosamprenavir) Containing Regimens In HIV-1 Infected Subjects [Phase 3]
A Phase 3 study evaluating regimens containing GW433908 (fosamprenavir) in HIV-1 infected subjects has completed, and results were posted in…
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CLINICAL_TRIALS trial_result · 2011-11-08Clinical Trial Update: Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis [Phase 3]
A Phase 3 trial conducted by All India Institute of Medical Sciences evaluating thrice-weekly Directly Observed Treatment, Short-Course (DOT…
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Drug Interaction Study Between Dolutegravir and Prednisone [Phase 1]
A Phase 1 study evaluating the interaction between dolutegravir and prednisone has been completed.
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CLINICAL_TRIALS trial_result · 2011-11-02Clinical Trial Update: GEMINI Study - A Study of Saquinavir/Ritonavir in Treatment-Naive Patients With HIV-1 Infection [Phase 3]
Phase 3 trial update for a fixed-dose combination of saquinavir/ritonavir in treatment-naive HIV-1 infection; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-11-02Clinical Trial Update: Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis [Phase 4]
A Phase 4 trial comparing immediate versus deferred initiation of antiretroviral therapy in HIV-infected adults undergoing tuberculosis trea…
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CLINICAL_TRIALS trial_result · 2011-11-01Clinical Trial Update: Etravirine Plus 2 Analogs in HIV-infected Patients
A completed clinical trial evaluating etravirine in combination with two analogs in HIV infection.
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CLINICAL_TRIALS trial_result · 2011-11-01Clinical Trial Update: Impact of Maraviroc on the Immune Function in HIV-1 Infected Subjects Receiving Immunisation With Novel Antigens [Phase 4]
Phase 4 trial evaluating the effect of maraviroc on immune responses to novel antigens in HIV-1 infected individuals; the study was terminat…
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CLINICAL_TRIALS trial_result · 2011-10-31Clinical Trial Update: Interactions Between Antiretrovirals (ARVs) and Combined Oral Contraceptives (COCs) [Phase 4]
Phase 4 clinical trial update examining interactions between antiretrovirals and combined oral contraceptives; the study status is completed…
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CLINICAL_TRIALS trial_result · 2011-10-28Clinical Trial Update: RAL-eve Study: Raltegravir Substitution Study [NA]
A completed clinical trial update (RAL-eve) evaluating substitution of raltegravir in HIV infection. Results were posted on 2011-10-28.
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CLINICAL_TRIALS trial_result · 2011-10-25Clinical Trial Update: MK-0518 Intensification And HDAC Inhibition In Depletion Of Resting CD4+ T Cell HIV Infection [Phase 2]
Phase 2 trial evaluating MK-0518 (raltegravir) intensification with histone deacetylase inhibition to deplete resting CD4+ T cell HIV infect…
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CLINICAL_TRIALS trial_result · 2011-10-25Clinical Trial Update: A Pilot Study to Characterize the Pharmacokinetics of Raltegravir in the Cervicovaginal Fluids of HIV-infected Women
This clinical trial update reports findings from a pilot study characterizing how raltegravir distributes in cervicovaginal fluids of HIV-in…