HIV Infection
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'
A completed clinical trial update examining how ageing affects pharmacokinetics and clinical observations in HIV-positive individuals; resul…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps) [Phase 3]
Phase 3 clinical trial (PrEPSteps) evaluating ingestible biosensors to improve adherence to HIV PrEP in people who use substances has comple…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection [Phase 3]
Phase 3 study update for Lenacapavir as HIV pre-exposure prophylaxis in at-risk individuals, with results posted on 2025-09-17 and the trial…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: A Waiting Room-Delivered Video to Enhance Clinical Outcomes Among Persons Living With HIV [NA]
A completed clinical trial evaluating a waiting-room-delivered video intervention to improve clinical outcomes among people living with HIV.
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Improving the HIV PrEP Cascade Using an Intervention for Healthcare Providers [NA]
Completed clinical trial update evaluating an intervention for healthcare providers to improve the HIV PrEP care cascade. The study status i…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: The Impact of Insomnia on Pain in HIV
Completed clinical trial from University of Alabama at Birmingham examining how insomnia affects pain in people living with HIV.
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Personalized Prevention for Couples: A 16-month Digital RCT [NA]
The 16-month digital randomized controlled trial on personalized prevention for couples has completed; no results are provided in the snippe…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: PRO 140 in Treatment-Experienced HIV-1 Subjects [Phase 2, Phase 3]
CytoDyn's PRO 140 (leronlimab) in treatment-experienced HIV-1 infection completed Phase 2/3 trials and posted results.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Podcasting HIV Prevention Within African American Communities [NA]
This completed clinical trial from the University of Houston evaluated HIV prevention strategies in African American communities; results we…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Mental Health Support for Transgender and Gender-expansive Individuals [NA]
A completed clinical trial assessing mental health support for transgender and gender-expansive individuals; results were posted on 2025-09-…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Integrated Care Delivery of HIV Prevention and Treatment in AGYW in Zambia [NA]
This clinical trial in Zambia evaluated integrated care delivery for HIV prevention and treatment among adolescent girls and young women; it…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Evaluation of (Doravirine / Lamivudine / Tenofovir Disoproxil Fumarate) (Delstrigo®) as a New Strategy for Non-occupational Post Exposure Prophylaxis, a Prospective Open Label Study [Phase 4]
Prospective open-label Phase 4 trial evaluating Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) as a non-occupational post-e…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Severe Impairment of Solute-Free Water Clearance in Patients With HIV Infection
The update describes severe impairment of solute-free water clearance observed in HIV-infected participants. This finding highlights a notab…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Individualized Antiretroviral Therapy [NA]
This is an update on a completed clinical trial evaluating individualized antiretroviral therapy guided by pharmacogenetics and drug monitor…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Youth to Text or Telehealth for Engagement in HIV Care [NA]
A completed clinical trial evaluating whether text-based or telehealth interventions improve engagement in HIV care among youth, including p…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: CD4 CAR+ ZFN-modified T Cells in HIV Therapy [Phase 1]
This entry notes a Phase 1 clinical trial evaluating CD4 CAR+ ZFN-modified T cells as a therapy for HIV, with the study currently active but…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Immune Response of Shingrix Vaccine in People Living With HIV (> 50 y.o.) Compared to Age-matched Controls [Phase 4]
Phase 4 trial evaluating the immune response to Shingrix in people living with HIV over 50 compared to age-matched controls; the study is cu…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Safety and Pharmacokinetics of Dolutegravir in Pregnant HIV Mothers and Their Neonates: A Pilot Study [Phase 2, Phase 3]
Phase 2/3 pilot study evaluating safety and pharmacokinetics of dolutegravir in pregnant women with HIV and their neonates; results have bee…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: A Clinical Trial to Evaluate the Safety and Immunogenicity of Glycan-trimmed HIV-1 Nanoparticle Vaccine (UVAX-1107), Followed by Homologous or Wild-type HIV-1 Nanoparticle Vaccine (UVAX-1197) Boost, Each Adjuvanted With 3M-052-AF + Alum in Adult Participants Without HIV [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of glycan-trimmed HIV-1 nanoparticle vaccine UVAX-1107, followed by UVAX-1197 booster…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: EASY-TESTS: Evaluation of the Acceptability of Pre-exposure Prophylaxis (PrEP) Among Men Who Have Sex With Men (MSM) Who Accepted Targeted HIV/STI Testing, Recruited Through a Community-based Outreach Approach, Both Digital and In-person.
Completed clinical trial evaluating the acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men recruited through t…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Contingency Management for Cannabis Use for Persons With HIV [NA]
The ClinicalTrials.gov entry indicates the contingency management trial to reduce cannabis use among people with HIV has completed. No resul…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Fecal Microbiota Translantation (FMT) to Reduce Inflammation in PLWH: The Gutsy Pilot Study [Phase 2]
This document reports the completion of a Phase 2 pilot trial evaluating fecal microbiota transplantation to reduce inflammation in people l…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Safety and PK Multi-dose Study of TAF/EVG Vaginal Insert [Phase 1]
A Phase 1 safety and pharmacokinetic study of a tenofovir alafenamide/elvitegravir vaginal insert has completed.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV [NA]
This clinical trial update reports the completed study evaluating an adapted resilience-building intervention for people aging with HIV, inc…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1 [Phase 1]
This Phase 1 trial assessed the safety, tolerability, and pharmacokinetics of dolutegravir in neonates exposed to HIV-1, and the study has c…