Hiv-associated Neurocognitive Disorder
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Working Memory Training for People Aging With HIV [EARLY_Phase 1]
Early phase 1 trial assessing working memory training for people aging with HIV has completed.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury [NA]
A clinical trial update from Wake Forest University Health Sciences reports ongoing recruitment for a study examining how chronic cannabis u…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy [Phase 1, Phase 2]
A Yale University-led study uses SV2A and TSPO PET imaging to investigate mechanisms of HIV neuropathogenesis in individuals on antiretrovir…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old
A completed clinical trial evaluating cognitive impairment in older adults with HIV infection. The study status is completed, with no detail…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Computerized Cognitive Rehabilitation of Patients With Cognitive Deficits Due to the Human Immunodeficiency Virus [NA]
This clinical trial is evaluating computerized cognitive rehabilitation for HIV-related cognitive dysfunction and is not yet recruiting.
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CLINICAL_TRIALS withdrawal · 2024-07-03Clinical Trial Update: Teleneuropsychological Intervention in Asymptomatic HIV Seropositive Patients: N&C NeuroChange [NA]
This clinical trial update notes that the Teleneuropsychological Intervention trial (N&C NeuroChange) in asymptomatic HIV-seropositive indiv…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Impact of Probiotics in HIV-positive Patients With Neurocognitive Disorders [NA]
A completed clinical trial evaluated the impact of probiotics in HIV-positive patients with HIV-associated neurocognitive disorder.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Exploring Racial Disparities in Sleep Health and Neurocognitive Function [NA]
A completed clinical study by the University of Alabama explored racial disparities in sleep health and neurocognitive function in HIV-assoc…
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Psychosocial Intervention for Older HIV+ Adults With HAND [NA]
A completed clinical trial evaluating a psychosocial intervention for older adults with HIV and HAND (HIV-associated neurocognitive disorder…
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CLINICAL_TRIALS trial_result · 2020-11-06Clinical Trial Update: Using Less Neurotoxic Drugs in Patients With HAND (MARAND-X) [Phase 4]
Phase 4 trial update on using less neurotoxic drugs in patients with HIV-associated neurocognitive disorder (HAND), currently terminated.
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: Identification and Quantification of HIV CNS Latency Biomarkers
This clinical trial explores identifying and quantifying biomarkers of HIV central nervous system latency, sponsored by St Vincent's Hospita…
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Observational Study of HIV-associated Neurocognitive Disorder
This clinical trial update reports the completion of an observational study evaluating HIV-associated neurocognitive disorder in people with…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Ferumoxytol-enhanced Brain MRI in HIV-associated Neurocognitive Disorders [Phase 1]
Phase 1 study evaluating ferumoxytol-enhanced MRI for HIV-associated neurocognitive disorder has been completed, sponsored by the University…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Effect of SwitChing AtriPla to Eviplera on Neurocognitive and Emotional Functioning [Phase 4]
Phase 4 study evaluating neurocognitive and emotional functioning after switching from AtriPla to Eviplera in people with HIV-associated neu…
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Does Micro-albuminuria is a Predictive Factor for Cognitive Impairment in Persons Living With HIV (PLHIV) Who Achieve cART-sustained Immunovirological Control ?
The document reports the completion of a clinical trial investigating whether micro-albuminuria can predict cognitive impairment in people l…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-based Regimen [NA]
Completed clinical trial evaluating brain imaging changes after switching from efavirenz to a raltegravir-based regimen in people with HIV, …
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder [Phase 1, Phase 2]
This clinical trial update reports the completion and results posting of a Phase 1/2 study evaluating paroxetine and fluconazole for HIV-ass…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Cognitive Remediation for HIV-associated Neurocognitive Dysfunction [NA]
The clinical trial NCT02671526 evaluating cognitive remediation for HIV-associated neurocognitive disorder has completed. Sponsored by Posit…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Assessment of the HIV CNS Reservoir, Neurological and Neuro-cognitive Effects, and Source of Rebound HIV in CNS
This update notes the completion of a clinical trial examining HIV persistence in the central nervous system and the associated neurological…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: COMO: Cognition Study With HIV+ Patients (CTNPT 015) [EARLY_Phase 1]
An early Phase 1 cognition study in HIV-positive patients (CTNPT 015) was terminated.
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CLINICAL_TRIALS research · 2015-10-23Clinical Trial Update: CogStim, a Pilot Study : Cognitive Rehabilitation Management of HIV-1 Mild Cognitively Impaired Patients Controlled With Antiretroviral Therapy [NA]
This document provides an update on CogStim, a pilot study evaluating cognitive rehabilitation for HIV-1-associated mild cognitive impairmen…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment. [Phase 2]
Phase II trial evaluating peptide T in HIV-positive individuals with cognitive impairment has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Prevalence of HIV-associated Neurocognitive Disorders (HAND) in a School of Medicine HIV/AIDS Outpatient Clinic
A completed clinical trial update from East Tennessee State University assessed how common HIV-associated neurocognitive disorder (HAND) is …
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: A Study of Dementia and Neurological Problems in HIV Infected Patients Who Are Participating in ACTG A5175
This ClinicalTrials.gov entry reports on dementia and neurological problems in HIV-infected patients enrolled in ACTG A5175; the trial has c…
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: HIV-1 Specific Immune Responses in Thai Individuals With HIV Dementia
This document announces the completion of a clinical trial investigating HIV-1 specific immune responses in Thai individuals with HIV dement…