High-grade Serous Ovarian Carcinoma
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors. [Phase 1]
A Phase 1 trial evaluating escalating doses of the investigational agent BMS-986463 to assess safety, tolerability, and early signals of act…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer [Phase 2]
A Phase 2 trial evaluating ONC-392 in combination with pembrolizumab for platinum-resistant ovarian cancer is active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Translational Study to Explore and Overcome Metabolic-driven Resistance Mechanisms to Standard Chemotherapy in High-grade Ovarian Cancer
This clinical trial update describes a translational study aiming to understand and overcome metabolic-driven resistance to standard chemoth…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer [Phase 1]
This clinical trial update announces the first-in-human, Phase 1 study of ATX-295, an oral inhibitor of KIF18A, in patients with advanced or…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: First in Human Study of IMGN151 in Recurrent Gynaecological Cancers [Phase 1]
This update covers the first-in-human Phase 1 study of IMGN151 in recurrent gynecologic cancers, sponsored by AbbVie, with the trial status …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy [NA]
Clinical trial update for the OV Precision study evaluating tumor- and patient-specific cancer therapy in ovarian and fallopian tube neoplas…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO) [Phase 3]
Phase 3 trial MATAO is evaluating maintenance therapy with an aromatase inhibitor in epithelial ovarian cancers; the study is currently recr…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer
Massachusetts General Hospital is sponsoring a study to develop a uterine lavage test for detecting ovarian cancer, and the trial is current…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: High Definition Profiling of Ovarian Cancer Ascites
Update on a clinical trial evaluating high-definition profiling of ovarian cancer ascites; the study is currently not yet recruiting.