High-grade Serous Ovarian Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Impact of Dietary Patterns on Prognosis of Ovarian Cancer Patients During PARPi Maintenance
A ClinicalTrials.gov update describes a study evaluating how dietary patterns affect prognosis for ovarian cancer patients during PARP inhib…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Minimal Residual Disease in Solid Malignancies [NA]
This clinical trial update describes a study evaluating minimal residual disease in solid malignancies across several cancers, and it is cur…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer [Phase 1, Phase 2]
Phase I/II study evaluating VLS-1488 in adults with advanced cancer; the trial is currently recruiting across multiple solid-tumor indicatio…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib [Phase 2]
A Phase 2 trial of Avutometinib (VS-6766) in combination with Defactinib is recruiting for several gynecologic cancers, including endometria…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study of Sovilnesib in Subjects With Ovarian Cancer [Phase 1]
Phase 1 study update of Sovilnesib in gynecologic cancers; the trial is active but not recruiting, investigating high-grade serous ovarian c…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Chemotherapy Combined With Propranolol Hydrochloride as Neoadjuvant Therapy for Advanced High-grade Serous Ovarian Cancer [Phase 2]
Phase 2 trial to assess neoadjuvant chemotherapy combined with propranolol hydrochloride for advanced high-grade serous ovarian cancer; stud…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: 68Ga-FAPI PET/CT in the Staging of High-Grade Epithelial Ovarian Cancers: A Pilot Study [NA]
This is a pilot study evaluating Ga-68 labeled FAPI PET/CT for staging high-grade epithelial ovarian cancers, including high-grade serous ov…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Investigating Idetrexed and Olaparib in Patients With Ovarian Cancer [Phase 1]
A Phase 1 clinical trial is evaluating the combination of idetrexed and olaparib in patients with high-grade serous ovarian cancer; the stud…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Pembrolizumab and Lenvatinib for the Treatment of Serous Ovarian Cancer Patients [Phase 2]
A Phase 2 clinical trial update describes the combination of pembrolizumab and lenvatinib for high-grade serous cancers of the fallopian tub…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer [Phase 2]
Phase 2 trial comparing MORAb-202 to investigator's choice chemotherapy in women with platinum-resistant high-grade serous ovarian cancer an…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: NIRAPK : Study of the Relationship(s) Between Clinical, Biological and Pharmacokinetic Metrics and Toxicities When Niraparib is Used as Maintenance Treatment for Ovarian Cancer Patients. [Phase 4]
A Phase 4 study investigating relationships between clinical, biological, and pharmacokinetic metrics and toxicities in ovarian cancer patie…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: IN10018 in Combination With Standard Chemotherapy in High-grade Serous Epithelial Ovarian Cancer [Phase 1, Phase 2]
A Phase 1/2 trial (IN10018) evaluating IN10018 in combination with standard chemotherapy for high-grade serous epithelial ovarian cancer is …
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Exploratory Study on HER2 Detection Method and Positive Threshold for High-grade Serous Adenocarcinoma of the Ovary
An exploratory clinical trial to refine HER2 detection criteria and positive thresholds in high-grade serous ovarian cancer and to observe t…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC) [Phase 1, Phase 2]
A clinical trial update indicates the Phase 1/2 study of KB-0742 in relapsed or refractory solid tumors, including platinum-resistant high-g…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Unravelling Tumour Biology In Ovarian Cancer With Precision Imaging [NA]
A clinical study from Institut du Cancer de Montpellier - Val d'Aurelle is exploring precision imaging for high-grade serous ovarian cancer.…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Prediction of Platinum Resistance and Prognosis of High-grade Serous Ovarian Cancer
This completed clinical trial investigates predictors of platinum resistance and prognosis in high-grade serous ovarian cancer to improve tr…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Role of RPL8 Protein Alterations in High-grade Serous Ovarian Carcinoma
A clinical trial is investigating the role of RPL8 protein alterations in high-grade serous ovarian cancer and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Combination of Olaparib and Navitoclax in Women with HGSC and TNBC [Phase 1]
A Phase 1 clinical trial evaluating the combination of olaparib and navitoclax in women with high-grade serous ovarian cancer and triple-neg…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: "Re-Stimulated" TILs and IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer [Phase 1]
Phase 1 clinical trial evaluating re-stimulated tumor-infiltrating lymphocytes (TILs) with interleukin-2 for platinum-resistant recurrent ca…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Phase 1 Study to Evaluate the Safety, Feasibility and Immunogenicity of an Allogeneic, Cell-based Vaccine (DCP-001) in High Grade Serous Ovarian Cancer Patients After Primary Treatment [Phase 1]
Phase 1 clinical trial evaluating the safety, feasibility, and immunogenicity of DCP-001, an allogeneic cell-based vaccine, in patients with…
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer (UP-NEXT) [Phase 3]
A Phase 3 trial of Upifitamab Rilsodotin (Upifitamab Rilsodotin) in maintenance therapy for platinum-sensitive recurrent ovarian cancer has …
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246 [Phase 1, Phase 2]
Phase Ib/II trial evaluating carboplatin with or without APR-246 (eprenetapopt) for platinum-sensitive recurrent high-grade serous ovarian c…
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CLINICAL_TRIALS trial_result · 2022-07-21Clinical Trial Update: p53 Activation in Platinum-Resistant High Grade Serous Ovarian Cancer, a Study of PLD With APR-246 [Phase 2]
Phase 2 study evaluating pegylated liposomal doxorubicin with APR-246 in platinum-resistant high-grade serous ovarian cancer has completed, …
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CLINICAL_TRIALS trial_result · 2020-02-07Clinical Trial Update: NUVOLA TRIAL Open-label Multicentre Study [Phase 2]
A Phase 2 open-label multicentre trial called NUVOLA in high-grade serous ovarian cancer is described, with Phase 2 status and unknown ongoi…