Heterozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS trial_result · 2014-03-03Clinical Trial Update: Exploratory Study of Plaque Regression [Phase 2]
A Phase 2 exploratory trial evaluating plaque regression in patients with heterozygous familial hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158) [Phase 1]
Phase 1 trial of extended-release niacin/laropiprant in adolescents with heterozygous familial hypercholesterolemia was terminated; results …
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CLINICAL_TRIALS trial_result · 2012-09-03Clinical Trial Update: Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care [Phase 3]
A Phase 3 study of eprotirome in patients with heterozygous familial hypercholesterolemia was terminated.
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FDA approval · 2012-02-28FDA Approved: LESCOL XL — Supplemental Application (Sandoz Inc)
FDA approved a supplemental application for LESCOL XL (fluvastatin sodium) filed by Sandoz Inc.
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CLINICAL_TRIALS trial_result · 2012-01-18Clinical Trial Update: Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE. [Phase 2, Phase 3]
Phase 2/3 study of Pactimibe (CS-505) for reducing progression of carotid artery disease was terminated. The update summarizes the observed …
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FDA approval · 2011-12-01FDA Approved: VYTORIN — Supplemental Application (Organon LLC)
FDA approved a supplemental application for VYTORIN (ezetimibe and simvastatin) by Organon LLC, updating its labeling and indications.
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CLINICAL_TRIALS trial_result · 2011-11-08Clinical Trial Update: Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia [Phase 3]
Phase 3 trial evaluating the efficacy and safety of fluvastatin in children with heterozygous familial hypercholesterolemia; the study has c…
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CLINICAL_TRIALS trial_result · 2010-08-20Clinical Trial Update: 8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia [Phase 1]
Phase 1 PK/PD study of atorvastatin in children and adolescents with heterozygous familial hypercholesterolemia has completed with results p…