Heterozygous Familial Hypercholesterolemia
📧 Sign up to get email alerts when something new happens for Heterozygous Familial Hypercholesterolemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-07-17Clinical Trial Results: A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1) [Phase 2]
Phase 2 clinical trial in children aged 6 to 17 with heterozygous familial hypercholesterolemia evaluating once-daily bempedoic acid (CLEAR …
-
CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
Verve Therapeutics reports long-term follow-up data from participants treated with its investigational gene-editing therapy for cardiovascul…
-
CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: A Study to Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) [Phase 3]
A Phase 3 study to evaluate SYH2053 Injection in patients with heterozygous familial hypercholesterolemia. The trial status is not yet recru…
-
CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Early-phase Study of ART002g1 Injection in HeFH: Safety, Tolerability and Preliminary Efficacy [EARLY_Phase 1]
This document reports an early-phase (Phase 1) study of ART002g1 injection for heterozygous familial hypercholesterolemia, focusing on safet…
-
CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH [Phase 3]
This document reports a Phase III clinical trial evaluating AZD0780's effect on LDL-C in patients with heterozygous familial hypercholestero…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) [Phase 2]
MGL-3196 (resmetirom), developed by Madrigal, completed a Phase 2 trial in patients with heterozygous familial hypercholesterolemia, with re…
-
CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1) [Phase 2]
A Phase 2 pediatric trial evaluating once-daily oral bempedoic acid in children aged 6 to 17 with heterozygous familial hypercholesterolemia…
-
CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease [Phase 1]
Phase 1 trial update reporting completion of the study of VERVE-101 in patients with heterozygous familial hypercholesterolemia and cardiova…
-
CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia [Phase 3]
A Phase 3 study evaluating the efficacy and safety of HST101 in Chinese patients with hypercholesterolemia and related dyslipidemias; the tr…
-
CLINICAL_TRIALS trial_result · 2024-03-18Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH). [Phase 3]
Phase 3 trial updating efficacy and safety of JS002 in patients with heterozygous familial hypercholesterolemia has completed.
-
CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction [Phase 3]
Phase 3 trial assessing LIB003 for further LDL-C reduction in adults with heterozygous familial hypercholesterolemia; study completed.
-
CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: Safety and Efficacy of IBI306 in HeFH Patients [Phase 3]
Phase 3 trial update on IBI306 in patients with heterozygous familial hypercholesterolemia assessing safety and efficacy.
-
CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C [Phase 2]
This Phase 2 study evaluated the efficacy and safety of Inclisiran in Japanese participants at high cardiovascular risk with elevated LDL-C.…
-
CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: A Study of PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) [Phase 2]
Phase 2 clinical trial of PCSK9 inhibitor AK102 in patients with heterozygous familial hypercholesterolemia has been completed.
-
CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia [Phase 3]
Phase 3 trial update evaluating PCSK9 inhibitors for efficacy and safety in patients with heterozygous familial hypercholesterolemia.
-
CLINICAL_TRIALS trial_result · 2021-06-15Clinical Trial Update: Long Term Safety Study of PRALUENT [Phase 4]
Phase 4 long-term safety study of PRALUENT has been terminated with results posted.
-
CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH) [Phase 3]
Phase 3 trial evaluating Inclisiran's effect on LDL-C in patients with heterozygous familial hypercholesterolemia has completed with results…
-
CLINICAL_TRIALS trial_result · 2020-08-05Clinical Trial Update: Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH) [Phase 2]
Open-label extension study to assess long-term safety and efficacy of alirocumab in heterozygous familial hypercholesterolemia completed wit…
-
CLINICAL_TRIALS trial_result · 2020-05-01Clinical Trial Update: Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy [Phase 3]
Phase 3 trial studying alirocumab in patients with heterozygous familial hypercholesterolemia undergoing LDL apheresis has completed with re…
-
CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia [Phase 2]
Phase 2 dose-finding trial evaluating alirocumab in children and adolescents with heterozygous familial hypercholesterolemia has been comple…
-
CLINICAL_TRIALS trial_result · 2018-01-11Clinical Trial Update: A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) [Phase 3]
Phase 3 clinical trial evaluating long-term safety and tolerability of MK-0653C in Japanese participants with hypercholesterolemia; complete…
-
CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia [Phase 3]
Phase 3, 52-week study of bococizumab in subjects with heterozygous familial hypercholesterolemia completed; results were posted in May 2017…
-
CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050) [Phase 3]
Phase 3 study evaluating safety and efficacy of adding Anacetrapib to ongoing statin therapy in Japanese participants with heterozygous fami…
-
CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Alirocumab added to lipid-modifying therapy in patients with heterozygous familial hyper…
-
CLINICAL_TRIALS trial_result · 2015-10-28Clinical Trial Update: Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy) [Phase 3]
Phase 3 study evaluating Alirocumab in patients with heterozygous familial hypercholesterolemia not adequately controlled on lipid-modifying…