Herpes Simplex Virus Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Neonatal Phase 1 Valacyclovir Study [Phase 1]
This clinical trial update reports the completed Phase 1 neonatal study of valacyclovir for herpes simplex infection, sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects [Phase 3]
Phase 3 trial evaluating pritelivir for acyclovir-resistant mucocutaneous herpes simplex virus infections in immunocompromised subjects has …
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL [Phase 3]
Phase 3 trial evaluating acyclovir in ventilated patients with pneumonia and HSV-1 detected in BAL is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Randomized, Placebo-controlled, Double-blind Study of 2LHERP® in Orofacial Herpes Infections. [Phase 4]
Phase 4 randomized, placebo-controlled, double-blind study of 2LHERP for orofacial herpes infections is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers [Phase 1]
Phase I trial update describes safety, tolerability, and pharmacokinetics of a single IM-250 dose in healthy volunteers for herpes simplex v…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Phase III Study of ASP2151 in Herpes Simplex Patients [Phase 3]
Phase III trial of ASP2151 for herpes simplex infection has completed, with results posted on 2024-10-09.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Potential Influence of Esomeprazole on the Pharmacokinetics of Pritelivir [Phase 1]
Phase 1 trial investigating how esomeprazole affects the pharmacokinetics of pritelivir in HSV infection.
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: Immune Response and General Immune Health in Subjects Infected With Herpes Simplex Virus Type 1 (HSV-1) [Phase 1]
A Phase 1 trial assessing immune response and general immune health in subjects infected with HSV-1 has completed with results posted in 202…
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CLINICAL_TRIALS trial_result · 2020-12-07Clinical Trial Update: Palatability Testing of a New Paediatric Formulation of Valacyclovir [Phase 4]
Phase 4 trial evaluating palatability of a new paediatric formulation of valacyclovir; completed.
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CLINICAL_TRIALS trial_result · 2018-02-12Clinical Trial Update: VALTREX Once Daily For Viral Shedding In Herpes Simplex Virus 2 (HSV-2) Seropositive Subjects. VALTREX® Tablet is a Trademark of GlaxoSmithKline Group of Companies. [Phase 4]
Phase 4 trial updating viral shedding results for VALTREX (valacyclovir) in HSV-2 seropositive subjects; study completed with results posted…
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CLINICAL_TRIALS trial_result · 2017-06-02Clinical Trial Update: Evaluation of Safety of Candidate gD Vaccine, With or Without MPL in Healthy Herpes Simplex Virus-positive Adults [Phase 1]
Phase 1 safety evaluation of a glycoprotein D vaccine (gD vaccine) for herpes simplex virus in HSV-positive healthy adults, with and without…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the Blood [NA]
A completed clinical trial evaluated whether acyclovir treatment of herpes simplex virus infection affects HIV levels in the blood.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Valacyclovir Augmentation for Cognitive and Functional Remediation in Schizophrenia [Phase 4]
Phase 4 trial evaluating valacyclovir augmentation for cognitive and functional remediation in schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2? [Phase 3]
A Phase 3 trial investigated whether valacyclovir can attenuate inflammation in people with HIV on antiretroviral therapy who are co-infecte…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: A Retrospective Chart Review Study of Gene-Eden-VIR/Novirin
Completed retrospective chart review evaluating the antiviral supplement Gene-Eden-VIR/Novirin across multiple viral infections to assess ou…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: A Two Arm, Multi-Site Clinical Evaluation of the ARIES HSV 1&2 Assay in Symptomatic Patients
This document reports a completed two-arm, multi-site clinical evaluation of the ARIES HSV 1&2 Assay in symptomatic patients.
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CLINICAL_TRIALS trial_result · 2015-04-17Clinical Trial Update: Safety and Effectiveness of Tenofovir Gel in the Prevention of Human Immunodeficiency Virus (HIV-1) Infection in Women and the Effects of Tenofovir Gel on the Incidence of Herpes Simplex Virus (HSV-2) Infection [Phase 3]
Phase 3 trial evaluating the safety and effectiveness of 1% tenofovir gel to prevent HIV-1 infection in women, and its effect on HSV-2 incid…
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Valacyclovir vs. Acyclovir as HSV-2 Suppressive Therapy: Effect on Plasma HIV-1 Levels Among HIV-1/HSV-2 Co-infected Persons [Phase 4]
Phase 4 trial comparing valacyclovir to acyclovir for suppression of herpes simplex virus type 2 in people co-infected with HIV-1, with meas…
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CLINICAL_TRIALS trial_result · 2014-01-08Clinical Trial Update: A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo) [Phase 1]
Phase 1 pharmacokinetics study of acyclovir in premature infants completed; results posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Acyclovir in Preventing Herpes Simplex Virus Infection in Patients With Neutropenia [Phase 3]
Phase 3 trial evaluating acyclovir to prevent herpes simplex virus infection in neutropenic patients has completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2013-08-22Clinical Trial Update: HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Persons [Phase 3]
This update reports the completion of a Phase 3 trial testing whether HSV-2 suppression lowers HIV-1 viral levels in individuals co-infected…
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CLINICAL_TRIALS trial_result · 2013-08-22Clinical Trial Update: HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men. [Phase 3]
Phase 3 trial evaluating HSV-2 suppression to reduce HIV-1 levels in men co-infected with HIV-1 and HSV-2 has completed.
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CLINICAL_TRIALS trial_result · 2011-03-01Clinical Trial Update: Comparison of Brovavir Versus Acyclovir in the Treatment of Herpes in HIV-Infected Patients [Phase 2]
Phase 2 randomized trial comparing Brovavir to Acyclovir for herpes in HIV-infected patients has completed.
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Seroprevalence Study of Hepatitis A, Varicella-Zoster, Cytomegalovirus, Herpes Simplex and Bordetella Pertussis
GlaxoSmithKline-sponsored seroprevalence study assessing antibodies to Hepatitis A, Varicella-zoster virus, Cytomegalovirus, Herpes simplex,…
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CLINICAL_TRIALS trial_result · 2010-12-14Clinical Trial Update: Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infection [Phase 2]
Phase 2 study evaluating pharmacokinetics, acceptability, and safety of famciclovir in infants aged 1 month to less than 12 months with herp…