Hereditary Angioedema
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Study of Clinical, Biological Characteristics and Quality of Life of Patients With Hereditary or Acquired Non Drug-induced Bradykinin-mediated Angioedema, Monitored in Besançon's Partner Site Reference Center for Studies of Kinin-mediated Angioedema (CREAK)
Completed clinical study conducted at Besançon assessing clinical and biological characteristics and quality of life in patients with heredi…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor [Phase 2]
Phase 2 study evaluating recombinant human C1 esterase inhibitor for hereditary angioedema prophylaxis has completed. Results were posted De…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions [Phase 1]
A Phase 1 drug-drug interaction study evaluating transporter interactions completed for a BioCryst-sponsored compound being developed for he…
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe Substrates [Phase 1]
An open-label Phase 1 study evaluating whether BCX7353 affects cytochrome P450 enzyme activity using probe substrates to assess potential dr…
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: A Call Center During HAE Attacks (SOS HAE) [Phase 4]
Phase 4 clinical trial SOS HAE, evaluating a call center during hereditary angioedema attacks, has completed. The entry confirms the study s…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE [Phase 4]
Phase 4 clinical trial update reporting results on icatibant for hereditary angioedema, focusing on efficacy, safety and tolerability.
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: A Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 in Hereditary Angioedema Participants [Phase 1]
Phase 1 trial update for DX-2930 in hereditary angioedema assessing safety, tolerability, and pharmacokinetics.
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary Angioedema [Phase 3]
Open-label, long-term safety study of Avoralstat in hereditary angioedema (Phase 3) has been terminated.
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CLINICAL_TRIALS trial_result · 2016-01-13Clinical Trial Update: First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BCX7353 in Healthy Western and Japanese Volunteers [Phase 1]
First-in-human Phase 1 study evaluating BCX7353 for safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy volunteers with …
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CLINICAL_TRIALS trial_result · 2015-11-16Clinical Trial Update: Postmarketing Immunogenicity Study in HAE Subjects Treated With Berinert [Phase 4]
A Phase 4 postmarketing study evaluating the immunogenicity of Berinert in patients with hereditary angioedema (types I and II) has been com…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks [Phase 3]
Phase 3 trial evaluating the efficacy, safety and immunogenicity of recombinant human C1 esterase inhibitor for the treatment of acute hered…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks [Phase 2]
Phase 2 trial evaluating subcutaneous CINRYZE with recombinant human hyaluronidase for prevention of angioedema attacks in hereditary angioe…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Study of Heparin Prophylaxis of Hereditary Angioedema Exacerbations [NA]
Completed clinical trial evaluating heparin prophylaxis to reduce exacerbations in hereditary angioedema.
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CLINICAL_TRIALS trial_result · 2015-01-14Clinical Trial Update: Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers [Phase 1]
Phase 1 open-label study assessing pharmacokinetics, safety, and tolerability of a single subcutaneous icatibant dose in healthy Japanese vo…
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CLINICAL_TRIALS trial_result · 2014-10-29Clinical Trial Update: Study to Determine How BCX4161 is Metabolized and Eliminated by the Body [Phase 1]
A Phase 1 study evaluating how BCX4161 is metabolized and eliminated in the human body for hereditary angioedema.
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Observational Safety Study for KALBITOR (Ecallantide) in the Treatment of Acute Attacks of Hereditary Angioedema
A completed observational safety study of ecallantide (KALBITOR) in treating acute hereditary angioedema attacks; results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: Safety and Efficacy of Oral BCX4161 as a Prophylactic Treatment for HAE [Phase 2]
Phase 2 trial evaluating oral BCX4161 as prophylaxis for hereditary angioedema has completed, reporting safety and efficacy outcomes.
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: A Study of the Relative Bioavailability of a New Formulation of BCX4161 and the Effect of Food on BCX4161 [Phase 1]
This Phase 1 trial assesses the relative bioavailability of a new formulation of BCX4161 and the effect of food on its absorption in heredit…
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: A Study of Icatibant in Patients With Acute Attacks of Hereditary Angioedema (FAST-3) [Phase 3]
Phase 3 trial of icatibant for acute attacks of hereditary angioedema completed with posted results.
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: EASSI - Evaluation of the Safety of Self-Administration With Icatibant [Phase 3]
Phase 3 trial evaluating the safety of self-administration with icatibant in hereditary angioedema has completed; results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12 [Phase 2]
Phase 2 trial update for CINRYZE in children under 12 with hereditary angioedema has completed with results posted.
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE) [Phase 3]
Phase 3 trial update of subcutaneous icatibant for acute attacks in hereditary angioedema; results posted after completion.
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CLINICAL_TRIALS trial_result · 2013-12-24Clinical Trial Update: Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema [Phase 3]
Phase 3 trial update evaluating subcutaneous icatibant for acute attacks of hereditary angioedema has completed with results posted.
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE [Phase 4]
Phase 4 trial evaluating escalating doses of CINRYZE for hereditary angioedema has completed with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-04-25Clinical Trial Update: Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema [Phase 2]
A Phase 2 study evaluating recombinant human C1 inhibitor for acute attacks in hereditary angioedema has completed.