Hereditary Angioedema
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: STOP-HAE: A Phase 3 Study of ADX-324 in HAE [Phase 3]
A Phase 3 trial (STOP-HAE) evaluating ADX-324 for hereditary angioedema (types I and II) is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Phase 2 in Adult Subjects With Hereditary Angioedema [Phase 2]
A Phase 2 clinical trial in adults with hereditary angioedema is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Survey of Lanadelumab in Participants With Hereditary Angioedema
A clinical trial update describing a survey of lanadelumab in participants with hereditary angioedema; the study is currently active but not…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study of Navenibart in Participants With Hereditary Angioedema [Phase 3]
A Phase 3 clinical trial to evaluate the safety and efficacy of Navenibart in participants with hereditary angioedema; the study is currentl…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Safety Study in Subjects ≥ 12 Years of Age With Hereditary Angioedema Switching to Garadacimab [Phase 4]
A Phase 4 safety study evaluating switching to garadacimab in subjects aged 12 years and older with hereditary angioedema is currently recru…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Learn About the C1-Inhibitor Function as Diagnosis for Hereditary Angioedema [NA]
A Takeda-sponsored clinical study aims to evaluate C1-inhibitor function as a diagnostic test for hereditary angioedema.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)
The document reports a clinical trial evaluating garadacimab for hereditary angioedema. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: NTLA-2002 in Adults With Hereditary Angioedema (HAE) [Phase 1, Phase 2]
An update on a Phase 1/2 clinical trial of NTLA-2002 for hereditary angioedema. The study is currently listed as active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE [Phase 3]
A long-term, open-label Phase 3 trial evaluating an oral extended-release deucrictibant tablet for prophylaxis of angioedema attacks in adol…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study About the Diagnosis and Management of Hereditary Angioedema (HAE) in Egypt
Takeda-sponsored clinical trial in Egypt focusing on the diagnosis and management of hereditary angioedema, with recruitment not yet started…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdema
A clinical trial update notes that a study assessing lived burden of hereditary angioedema using ecological momentary assessment is currentl…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE) [Phase 3]
Phase 3 extension study update for ADX-324 in hereditary angioedema; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of Lanadelumab in Children With Hereditary Angioedema (HAE) in Multiple Countries
A study evaluating lanadelumab for hereditary angioedema in children across multiple countries is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: HAELO: A Phase 3 Study to Evaluate NTLA-2002 in Participants With Hereditary Angioedema (HAE) [Phase 3]
Clinical trial update for NTLA-2002 in hereditary angioedema (HAE). It is a Phase 3 study sponsored by Intellia Therapeutics and is currentl…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE) [Phase 3]
This update concerns a Phase 3 study evaluating the long-term safety and efficacy of Donidalorsen for prophylaxis in hereditary angioedema; …
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Study of Lanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE)
This clinical trial update reports on lanadelumab being studied in teenagers and adults with hereditary angioedema; the study is currently a…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Survey of Icatibant in Pediatric Participants With Hereditary Angioedema
Takeda-sponsored pediatric trial evaluating icatibant for hereditary angioedema has completed. The trial identifier is NCT05509569.
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: A Long-Term Study of Navenibart in Participants With Hereditary Angioedema [Phase 3]
A long-term Phase 3 study evaluating Navenibart in participants with hereditary angioedema is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks [Phase 3]
Phase 3 clinical trial evaluating IV human plasma-derived C1 esterase inhibitor concentrate for treatment and pre-procedure prevention of ac…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: A Long-term Study of STAR-0215 in Participants With Hereditary Angioedema [Phase 2]
Update on the Phase 2 long-term study of STAR-0215 in participants with hereditary angioedema.
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial [Phase 3]
This document provides a clinical trial update on a pharmacokinetic subtrial in adolescent patients with hereditary angioedema types I or II…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Oral Deucrictibant for Prophylactic and Acute Treatment in Hereditary Angioedema Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating oral deucrictibant for prophylaxis and acute treatment in hereditary angioedema patients; recruitment …
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks
This document reports the completion of a clinical trial registry evaluating C1 inhibitor use for treatment of hereditary angioedema attacks…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases
This entry describes the Armenian nationwide registry of systemic autoimmune and autoinflammatory diseases, which is currently recruiting pa…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: HAE Burden and Crisis Management
Ongoing clinical trial update for NCT06806618 assessing the burden of hereditary angioedema and crisis management; the study is currently re…