Hepatocellular Carcinoma

• CLINICAL_TRIALS trial_result · 2022-04-27
  Clinical Trial Update: TACE vs TACE+SBRT for Unresectable Hepatocellular Cancer [Phase 2, Phase 3]

  Phase 2/Phase 3 trial comparing transarterial chemoembolization (TACE) alone versus TACE combined with stereotactic body radiotherapy (SBRT)…

• CLINICAL_TRIALS trial_result · 2022-04-15
  Clinical Trial Update: Phase 2 Study of TAC-101 Combined With Transcatheter Arterial Chemoembolization (TACE) Versus TACE Alone in Japanese Patients With Advanced Hepatocellular Carcinoma [Phase 2]

  This update reports termination of a Phase 2 randomized study evaluating TAC-101 in combination with transcatheter arterial chemoembolizatio…

• CLINICAL_TRIALS trial_result · 2022-04-14
  Clinical Trial Update: Surufatinib in Advanced Hepatocellular Carcinoma Based on Single-cell Sequencing of Tumor Samples [Phase 2]

  Phase 2 clinical trial update for Surufatinib in advanced hepatocellular carcinoma based on single-cell sequencing analyses.

• CLINICAL_TRIALS trial_result · 2022-04-05
  Clinical Trial Update: HAIC Combined With Anlotinib and TQB2450 as Adjuvant Therapy in HCC Patients With High Risk of Recurrence After Resection [Phase 2]

  Phase 2 clinical trial evaluating HAIC combined with Anlotinib and TQB2450 as adjuvant therapy for hepatocellular carcinoma patients at high…

• CLINICAL_TRIALS trial_result · 2022-04-04
  Clinical Trial Update: Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Advanced Hepatocellular Carcinoma (MK-3475-224/KEYNOTE-224) [Phase 2]

  Phase 2 study of pembrolizumab as monotherapy in advanced hepatocellular carcinoma (MK-3475-224/KEYNOTE-224) has completed with results post…

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• CLINICAL_TRIALS trial_result · 2022-03-31
  Clinical Trial Update: MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma [Phase 1, Phase 2]

  Phase 1/2 study comparing MLN0128 to sorafenib in advanced or metastatic hepatocellular carcinoma was terminated with results posted.

• CLINICAL_TRIALS trial_result · 2022-03-31
  Clinical Trial Update: Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors [Phase 2]

  Phase 2 trial exploring DPX-Survivac with low-dose cyclophosphamide and pembrolizumab in selected advanced solid tumors; currently active/no…

• CLINICAL_TRIALS trial_result · 2022-03-24
  Clinical Trial Update: A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC) [Phase 2]

  Phase 2 pilot study evaluating combined immune checkpoint inhibition with ablative therapies in hepatocellular carcinoma and biliary tract c…

• CLINICAL_TRIALS trial_result · 2022-03-18
  Clinical Trial Update: TAE and MWA Combination Therapy in Early-stage Hepatocellular Carcinoma [NA]

  A terminated early-stage hepatocellular carcinoma trial investigating transarterial embolization (TAE) and microwave ablation (MWA) did not …

• CLINICAL_TRIALS trial_result · 2022-03-16
  Clinical Trial Update: Surufatinib Alone or Combined With Anti-PD-1 mAb in the Treatment of Advanced Hepatocellular Carcinoma [Phase 2]

  Phase 2 trial evaluating surufatinib alone or with anti-PD-1 monoclonal antibody for advanced hepatocellular carcinoma; status not disclosed…

• CLINICAL_TRIALS trial_result · 2022-02-25
  Clinical Trial Update: Erlotinib Hydrochloride in Preventing Liver Cancer in Patients With Cirrhosis of the Liver [Phase 1, Phase 2]

  Clinical trial evaluating Erlotinib hydrochloride for prevention of liver cancer in patients with cirrhosis; study phases completed with res…

• CLINICAL_TRIALS trial_result · 2022-02-15
  Clinical Trial Update: Adjuvant Immunotherapy With Toripalimab Following Curative-intent Ablation for Recurrent Hepatocarcinoma [Phase 2]

  Phase 2 trial update evaluating adjuvant immunotherapy with toripalimab after curative-intent ablation for recurrent hepatocellular carcinom…

• CLINICAL_TRIALS trial_result · 2022-02-10
  Clinical Trial Update: A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With FOLFOX4 in Subjects With Advanced HCC Who Have Never Received Prior Systemic Treatment. [Phase 3]

  Clinical trial update for SHR-1210 (anti-PD-1) + FOLFOX4 in advanced hepatocellular carcinoma; Phase 3 study with unknown status.

• CLINICAL_TRIALS trial_result · 2022-02-07
  Clinical Trial Update: Accurate Dosimetry and Biomarkers Improve Survival in HCC Patients Treated With Resin 90 Yttrium (90Y)-Microspheres [Phase 2]

  A Phase 2 trial exploring accurate dosimetry and biomarkers for patients with hepatocellular carcinoma treated with resin 90Y microspheres t…

• CLINICAL_TRIALS trial_result · 2022-02-07
  Clinical Trial Update: Expanded Activated Lymphocytes (EAL) as Adjuvant Therapy in Patients With HCC at High Risk of Recurrence After Radical Resection [Phase 2]

  Phase 2 trial evaluating Expanded Activated Lymphocytes as adjuvant therapy to reduce recurrence in hepatocellular carcinoma after surgical …

• CLINICAL_TRIALS trial_result · 2022-02-01
  Clinical Trial Update: Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy [Phase 2]

  Phase 2 study of TAC-101 as second-line treatment in advanced hepatocellular carcinoma after sorafenib was terminated, with results posted.

• CLINICAL_TRIALS trial_result · 2022-01-27
  Clinical Trial Update: Effect and Safety of Recombinant Human Adenovirus Type 5 in Advanced HCC With Stable Disease After Sorafenib Treatment [Phase 4]

  Phase 4 clinical trial evaluating recombinant human adenovirus type 5 in advanced hepatocellular carcinoma patients with stable disease afte…

• CLINICAL_TRIALS trial_result · 2022-01-27
  Clinical Trial Update: P1101 and Anti-PD1 for After Curative Surgery of Hepatitis B-related Hepatocellular Carcinoma [Phase 1, Phase 2]

  A clinical trial update for P1101 and Anti-PD1 in patients after curative surgery for hepatitis B-related hepatocellular carcinoma, spanning…

• CLINICAL_TRIALS trial_result · 2022-01-26
  Clinical Trial Update: RFA or Surgical Resection Combined With Neo-MASCT for Primary HCC: a Phase II Trial [Phase 2]

  Phase II trial evaluating RFA or surgical resection combined with Neo-MASCT for primary hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2022-01-18
  Clinical Trial Update: Radiofrequency Ablation Plus Radiotherapy for Small Hepatocellular Carcinoma [Phase 3]

  Phase 3 trial investigating radiofrequency ablation plus radiotherapy for small hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2022-01-18
  Clinical Trial Update: HR Versus RFA for HCC in Patients With PHT [Phase 3]

  Phase 3 trial comparing HR versus RFA for hepatocellular carcinoma in patients with portal hypertension; status unknown.

• CLINICAL_TRIALS trial_result · 2022-01-12
  Clinical Trial Update: A Clinical Study Evaluating the Use of HLX10 in Combination With HLX04 for the Treatment of Advanced Hepatocellular Carcinoma (HCC) Patients [Phase 2]

  Phase 2 clinical trial update evaluating HLX10 in combination with HLX04 for advanced hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2022-01-12
  Clinical Trial Update: Bridge to Orthotopic Liver Transplantation (OLT) - Surefire Precision vs Endhole Embolization With DEBTACE [NA]

  Clinical trial evaluating a bridge-to-transplant approach for hepatocellular carcinoma patients awaiting liver transplantation; study termin…

• CLINICAL_TRIALS trial_result · 2022-01-05
  Clinical Trial Update: A Study to Evaluate TACE Sequential Tislelizumab as Adjuvant Therapy in Participants With HCC at High Risk of Recurrence After Curative Resection [Phase 2]

  Phase 2 study evaluating TACE sequential tislelizumab as adjuvant therapy for hepatocellular carcinoma at high risk of recurrence after cura…

• CLINICAL_TRIALS trial_result · 2021-12-30
  Clinical Trial Update: Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery [Phase 2]

  Phase 2 trial evaluating sorafenib tosylate in combination with Yttrium-90 glass microspheres for unresectable liver cancer (hepatocellular …