Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-09-16Clinical Trial Update: Safety and Efficacy of Mitomycin C-based HIPEC After srHCC and PM of HCC [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating mitomycin C–based HIPEC for hepatocellular carcinoma with peritoneal metastasis following srHCC…
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FDA approval · 2022-09-14FDA Approved: FLUOROURACIL — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for fluorouracil submitted by BluePoint Laboratories, indicating approval of an ANDA supplement. Thi…
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: A Study of Camrelizumab Combined With Rivoceranib Mesylate Versus Investigator's Choice of Regimen in Treatment of Patients With Advanced Hepatocellular Carcinoma (HCC) [Phase 3]
A Phase 3 trial evaluating camrelizumab plus rivoceranib mesylate versus investigator's choice in advanced hepatocellular carcinoma was term…
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CLINICAL_TRIALS research · 2022-08-29Clinical Trial Update: Sintilimab Combined With Lenvatinib Versus HAIC for Perioperative Treatment of Resectable Primary Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial evaluating sintilimab plus lenvatinib versus HAIC as perioperative therapy for resectable hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2022-08-26Clinical Trial Update: Gemcitabine With Oxaliplatin (GEMOX) in Patients With Advanced Hepatocellular Carcinoma After Failure of Sorafenib Treatment [Phase 2]
A phase 2 trial evaluating gemcitabine with oxaliplatin (GEMOX) in patients with advanced unresectable hepatocellular carcinoma after sorafe…
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CLINICAL_TRIALS trial_result · 2022-08-26Clinical Trial Update: Stereotactic Ablative Radiotherapy for Oligometastatic Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating stereotactic ablative radiotherapy for oligometastatic hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: HAIC Combined With Donafenib Tosilate and Toripalimab for Unresectable HCC [Phase 2]
Phase 2 clinical trial evaluating hepatic arterial infusion chemotherapy (HAIC) combined with donafenib and toripalimab for unresectable hep…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: A Pilot Study of "OncozeneTM" Microspheres for Intra-arterial Delivery of Doxorubicin [Phase 2]
Phase 2 pilot trial evaluating Oncozene microspheres for intra-arterial doxorubicin delivery in hepatocellular cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-08-16Clinical Trial Update: Effect of Propofol and Desflurane on Nucleic Acid of Liver Circulating Tumor [Phase 2]
Phase 2 clinical trial update evaluating the effects of propofol and desflurane on nucleic acids of liver circulating tumor cells in hepatoc…
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: Pembrolizumab in Advanced Hepatocellular Carcinoma as Second-line Treatment After Failure of Sorafenib [Phase 2]
Phase 2 trial evaluating pembrolizumab as second-line therapy for advanced hepatocellular carcinoma after sorafenib failure has completed wi…
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CLINICAL_TRIALS trial_result · 2022-07-25Clinical Trial Update: TACE With Dicycloplatin(TP21) in Unresectable HCC [Phase 3]
Clinical trial update for TACE with dicycloplatin (TP21) in unresectable hepatocellular carcinoma (Phase 3) with status currently unknown.
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Clinical Recruitment of Patients With First-line Targeted Drug Resistance or Intolerance to Hepatocellular Cancer With PD-1 Inhibitor (Toripalimab,JS001) Detected on the NGS Platform Combined With Anlotinib [Phase 2]
Phase 2 clinical trial exploring first-line combination therapy of toripalimab (PD-1 inhibitor) with anlotinib for hepatocellular carcinoma …
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CLINICAL_TRIALS trial_result · 2022-06-16Clinical Trial Update: A Trial of Hepatic Arterial Infusion Combined With Apatinib and Camrelizumab Versus Apatinib and Camrelizumab for C-staged Hepatocellular Carcinoma in BCLC Classification [Phase 3]
A Phase 3 trial comparing hepatic arterial infusion with Apatinib and Camrelizumab versus Apatinib and Camrelizumab for C-staged hepatocellu…
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CLINICAL_TRIALS trial_result · 2022-06-09Clinical Trial Update: Anti-PD-1 Antibody Plus DEB-TACE for BCLC Stage A/B HCC [Phase 2]
Phase 2 trial update investigating anti-PD-1 antibody in combination with DEB-TACE for hepatocellular carcinoma (BCLC A/B).
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FDA approval · 2022-06-07FDA Approved: SORAFENIB — Original Application (Dr.Reddys Laboratories Inc)
FDA approves the original application for a generic sorafenib product from Dr. Reddy's Laboratories Inc, expanding access to the cancer drug…
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CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: Efficacy and Safety of T+A+RAD in HCC [Phase 2]
Phase 2 clinical trial update on efficacy and safety of T+A+RAD in hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2022-05-25Clinical Trial Update: RCT of Different Effects of Nucleot(s)Ide Analogues on the Prognosis of HBV-HCC Patients After Curative Resection [Phase 4]
A Phase 4 clinical trial evaluating different nucleoside analogue regimens on prognosis after curative resection in HBV-related hepatocellul…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Hepatic Arterial Infusion of Raltetrexed With Oxaliplatin(SALOX) Versus FOLFOX in Advanced Hepatocellular Carcinoma [Phase 3]
Phase 3 trial comparing hepatic arterial infusion raltetrexed with oxaliplatin (SALOX) vs FOLFOX in advanced hepatocellular carcinoma is ong…
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: TACE Combined With Lenvatinib Versus TACE Sequential Lenvatinib in the Treatment of Intermediate/Advanced Liver Cancer [Phase 3]
Phase 3 trial comparing TACE plus Lenvatinib versus TACE followed by Lenvatinib in hepatocellular carcinoma (liver cancer). Status is unknow…
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: Bevacizumab Biosimilar Plus FOLFOX4 in the Treatment of Recurrent HCC After Liver Transplantation [Phase 2]
Phase 2 trial evaluating bevacizumab biosimilar with FOLFOX4 for recurrent hepatocellular carcinoma after liver transplantation.
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CLINICAL_TRIALS withdrawal · 2022-05-05Clinical Trial Update: A Clinical Study to Compare the Efficacy and Safety of HLX10 in Combination With HLX04 Versus Sorafenib as the First-line Treatment in Patients With Locally Advanced or Metastatic HCC [Phase 3]
A Phase 3 trial comparing HLX10+HLX04 to sorafenib as first-line treatment in hepatocellular carcinoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: A Trial of Hepatic Arterial Infusion Combined With Bevacizumab and Sintilimab for Unresectable A-staged Hepatocellular Carcinoma in BCLC Classification (D-TRIPLET) [Phase 2]
Phase 2 trial assessing hepatic arterial infusion with bevacizumab and sintilimab for unresectable hepatocellular carcinoma (BCLC A-stage).
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CLINICAL_TRIALS trial_result · 2022-05-04Clinical Trial Update: TQB2450 Plus Anlotinib as Adjuvant Therapy in HCC Patients at High Risk of Recurrence After Resection [Phase 2]
Phase 2 trial evaluating TQB2450 plus anlotinib as adjuvant therapy for hepatocellular carcinoma at high risk of recurrence after surgical r…
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: HLX07 Combination Therapy or Motherapy in Patient With Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial update for HLX07 combination therapy in patients with advanced hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Clinical Efficacy and Safety of NKT Cell Infusion in Patients With Advanced Solid Tumor [Phase 1, Phase 2]
Phase 1/2 trial update evaluating NKT cell infusion for advanced solid tumors, with indications including non-small cell lung cancer and gas…