Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors [Phase 2]
A Phase II trial of cabozantinib for hepatocellular carcinoma refractory to PD-1 inhibitors has completed.
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Prospective Collection of Therapeutic Efficacy and Safety Data in Patients with Unresectable Hepatocellular Carcinoma
ClinicalTrials.gov entry for a prospective study collecting efficacy and safety data in patients with unresectable hepatocellular carcinoma.…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: An Organoid-on-chips Technique Based on Biopsy Samples and Its Efficacy in Predicting the Response to HAI in HCC
This clinical trial update describes an organoid-on-a-chip system derived from biopsy samples and its potential to predict response to hepat…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: The Favorable Impact of HBcAb Positive Grafts on Liver Transplantation for HBV-related HCC
A completed clinical trial update reports favorable outcomes with HBcAb-positive donor grafts in liver transplantation for HBV-related hepat…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Multi-modal Characterisation of Hepatocellular Carcinoma (HCC) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort [NA]
A prospective interventional multicentre national cohort investigating hepatocellular carcinoma treated with targeted radionuclide therapy (…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic With Advanced HCC
This clinical trial investigates whether measurements of liver and spleen stiffness can predict the presence of esophageal varices in patien…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: BioPearl™ Microspheres Loaded With Doxorubicin for the Treatment of Unresectable Hepatocellular Carcinoma (HCC) [NA]
This clinical trial update notes that Terumo Europe N.V. is recruiting for a study of BioPearl microspheres loaded with doxorubicin to treat…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: MSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients with Cirrhosis
Clinical trial evaluating the MSEPT9 biomarker for predicting hepatocellular carcinoma occurrence in patients with cirrhosis; the study is n…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Neoadjuvant Nivolumab with CCR2/5-inhibitor or Anti-IL-8) for Non-small Cell Lung Cancer (NSCLC) or Hepatocellular Carcinoma (HCC) [Phase 2]
Phase 2 neoadjuvant trial evaluating nivolumab with a CCR2/5 inhibitor or anti-IL-8 in non-small cell lung cancer and hepatocellular carcino…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Immunophenotype of PBMC to Early Predict Response to Immunotherapy in Hepatocellular Carcinoma
A clinical trial investigates whether immunophenotyping peripheral blood mononuclear cells can early predict response to immunotherapy in he…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: A Clinical Trial Assessing the Safety and Efficacy of Biodegradable Magnesium Embolic Microspheres for Primary Hepatocellular Carcinoma [Phase 3]
Phase 3 clinical trial evaluating the safety and efficacy of biodegradable magnesium embolic microspheres for non-resectable hepatocellular …
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Atezolizumab and Bevacizumab in Combination With TACE for Patients With BCLC B HCC [Phase 2]
A Phase 2 trial evaluating Atezolizumab with Bevacizumab in combination with transarterial chemoembolization for patients with BCLC B hepato…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Recurrence Patterns and Cost-Effectiveness of Surgical Approaches in Early-Stage Hepatocellular Carcinoma
This trial completion update analyzes recurrence patterns and cost-effectiveness of different surgical approaches for early-stage hepatocell…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Can Hepatic-splenic Elastography Predict the Risk of Hepatocellular Recurrence After Radiofrequency Ablation?
An ongoing clinical study is evaluating whether hepatic-splenic elastography can predict recurrence risk after radiofrequency ablation for h…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Circulating Cell-free DNA-based Epigenetic Biomarker MSEPT9 for Hepatocellular Carcinoma Detection in Cirrhosis [NA]
This clinical trial update reports on using circulating cell-free DNA methylation biomarker MSEPT9 to detect hepatocellular carcinoma in pat…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Intra Artherial Therapies in Treatment of Primary Liver Diseases: an Observational Study
An observational study evaluating intra-arterial therapies for primary liver diseases, including hepatocellular carcinoma and cholangiocarci…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Use of Machine-learning Algorithms, Biomarkers and Measures of Quality of Life to Personalize Medical Management of Liver and Heart Transplant Recipients
Clinical trial update on using machine-learning, biomarkers, and quality-of-life measures to personalize care for liver and heart transplant…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Study of Oligo-Fucoidan in Advanced Hepatocellular Carcinoma (HCC) [NA]
A clinical trial evaluating Oligo-Fucoidan for advanced hepatocellular carcinoma has been terminated; no results are provided in the update.
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: TIPS Combined With Lenvatinib and PD-1 Inhibitor for Advanced HCC With Main Trunk PVTT [NA]
Clinical trial update describing a study of combining transjugular intrahepatic portosystemic shunt (TIPS) with lenvatinib and a PD-1 inhibi…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Composite Warming Strategy Reduces Intraoperative Hypothermia in Open Hepatectomy for Liver Cancer [NA]
A clinical trial update reports that a composite warming strategy reduces intraoperative hypothermia during open hepatectomy for hepatocellu…
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CLINICAL_TRIALS other · 2025-01-10Clinical Trial Update: Part of the Modern Art Study [NA]
A status update for the Modern Art Study (NCT06768242) indicating the trial is not yet recruiting for hepatocellular carcinoma and liver met…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation
A clinical trial update describing a study that compares the incidence of delirium in liver transplant patients when different anesthetic ag…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers [Phase 2]
This Phase 2 trial aims to evaluate whether reducing the dosing frequency of immune checkpoint inhibitors is feasible across advanced cancer…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer [Phase 2]
This Phase 2 trial update indicates recruitment is ongoing to compare stereotactic radiosurgery versus radiofrequency ablation for hepatocel…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Tislelizumab or Tislelizumab Combined With Lenvatinib Neo-adjuvant Treatment for Resectable RHCC [Phase 2]
This update describes a Phase 2 clinical trial evaluating tislelizumab alone or with lenvatinib as neoadjuvant treatment for resectable recu…