Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Prognostic Factors for HCC and Liver Transplantation in Patients With MASLD/MASH
A clinical trial evaluating prognostic factors for hepatocellular carcinoma and liver transplantation in patients with MASLD/MASH; recruitme…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Study of Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With Unresectable Hepatocellular Carinoma [Phase 3]
A Phase 3 clinical trial evaluating first-line durvalumab plus tremelimumab in Chinese patients with unresectable hepatocellular carcinoma i…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: HAIC Combined with Donafenib and Sintilimab As Perioperative Treatment for Resectable Hepatocellular Carcinoma Patients At High Risk of Recurrence [Phase 2]
This Phase 2 trial investigates perioperative use of hepatic arterial infusion chemotherapy combined with donafenib and sintilimab for patie…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma
This clinical trial, sponsored by Sun Yat-sen University, is recruiting to evaluate HAIC combined with lenvatinib and a PD-1 inhibitor for i…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation [NA]
A clinical trial evaluating bariatric embolization of arteries in obese patients with hepatocellular carcinoma to enable salvage liver trans…
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CLINICAL_TRIALS withdrawal · 2025-02-05Clinical Trial Update: Effect of Surefire Infusion Device on Tumor Response to Regional Intra-arterial Therapy for Primary Liver Malignancies [Phase 4]
A Phase 4 trial assessing the Surefire Infusion Device in regional intra-arterial therapy for primary liver malignancies has been withdrawn.…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Atezolizumab-bevacizumab and Other Immunotherapies: Real-life Experience for Treatment of Hepatocellular Carcinoma
This clinical trial update reports on real-life use of atezolizumab-bevacizumab and other immunotherapies for hepatocellular carcinoma; the …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study of Pembrolizumab Following TACE in Primary Liver Carcinoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating pembrolizumab following transarterial chemoembolization in hepatocellular carcinoma to assess safety …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 (Erdafitinib) in Participants With Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating erdafitinib (JNJ-42756493) in patients with advanced hepatocellular carcinoma has completed, assessing safety, …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Phase 1/2 Study to Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene [Phase 1, Phase 2]
Phase 1/2 study of OTX-2002 in hepatocellular carcinoma and other solid tumors has been terminated.
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Sarcopenia and Systemic Therapy in HCC
A trial titled 'Sarcopenia and Systemic Therapy in Hepatocellular Carcinoma' conducted by IRCCS Azienda Ospedaliero-Universitaria di Bologna…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Dose Escalation Study of Cabozantinib for Advanced HCC Patients With Preserved Liver Function [Phase 2]
A Phase 2 dose-escalation trial of cabozantinib in advanced hepatocellular carcinoma with preserved liver function has completed, focusing o…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Cabozantinib for Patients with Hepatocellular Carcinoma (HCC) Refractory to First Line Treatment [Phase 2]
A Phase 2 trial of cabozantinib for hepatocellular carcinoma refractory to first-line therapy has completed, including non-resectable or met…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Ex-vivo Hypotermic Perfusion in Patients With Hepatocellular Carcinoma to Reduce the Incidence of Tumor Recurrence
Completed clinical trial evaluating ex-vivo hypothermic, oxygenated machine perfusion of donor livers in hepatocellular carcinoma patients u…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers
This completed trial developed molecular classification models for early diagnosis of digestive system cancers and assessed their ability to…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: SIR-Spheres Study to Calculate the Radiation-Absorbed Dose of 99mTc-MAA [Phase 4]
Sirtex Medical conducted a Phase 4 trial to calculate the radiation-absorbed dose of 99mTc-MAA used in planning SIR-Spheres Y-90 microsphere…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Validation of the TRAIN-AI for the Risk of HCC Recurrence After Liver Transplantation
This update reports the completed validation study of TRAIN-AI, an AI model, for predicting hepatocellular carcinoma recurrence after liver …
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma [NA]
A single-arm, open-label study of SZ003 for advanced hepatocellular carcinoma has been terminated.
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Fusing Ultrasound and Magnetic Resonance Imaging to Intelligently Plan Highly Conformal Ablation Thermal Field for Hepatocellular Carcinoma
This clinical trial update describes a fused ultrasound and magnetic resonance imaging approach to plan highly conformal ablation therapy fo…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Lenvatinib Plus DEB-TACE and HAIC vs. Lenvatinib Plus DEB-TACE for Large HCC With PVTT [Phase 3]
Phase 3 trial comparing lenvatinib plus DEB-TACE with HAIC versus lenvatinib plus DEB-TACE in patients with large hepatocellular carcinoma a…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Y-90 SIRT for Unresectable HCC Larger Than 7cm [Phase 2]
A Phase 2 clinical trial evaluating yttrium-90 selective internal radiation therapy for unresectable hepatocellular carcinoma larger than 7 …
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: A Prospective Cohort Study of Patients with Hepatobiliary Cancer Treated with Immune Checkpoint Inhibitors
This is a prospective cohort study evaluating immune checkpoint inhibitors in hepatobiliary cancers. The trial is currently active but not r…
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FDA approval · 2025-01-27FDA Approved: CYRAMZA — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for CYRAMZA (ramucirumab) from Eli Lilly and Company.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: A Phase 1 Study of BPI-371153 in Subjects with Advanced Solid Tumors or Relapsed/Refractory Lymphoma [Phase 1]
Phase 1 trial of BPI-371153 in advanced solid tumors and lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Ga-68 Dolacga PET Scan in HCC Under RFA
A National Taiwan University Hospital trial is evaluating Ga-68 Dolacga PET imaging for hepatocellular carcinoma under radiofrequency ablati…