Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Safety and Efficacy of Metabolically Armed GPC3 CAR-T Cells Injection (Meta10-GPC3) in Patients With Unresectable Recurrent/Metastatic Hepatocellular Carcinoma [EARLY_Phase 1]
Early-phase trial investigating the safety and efficacy of Meta10-GPC3 GPC3-targeted CAR-T cells in unresectable recurrent/metastatic hepato…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer
Clinical trial update on a precision-based immunotherapy program for primary liver cancer, currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Becotatug Vedotin (MRG003) in Previously Treated Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial update for Becotatug Vedotin (MRG003) in previously treated advanced hepatocellular carcinoma; study is currently rec…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
Clinical trial registry entry for real-world evaluation of HistoSonics' Edison System for treating liver tumors; study is currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI [NA]
A clinical trial comparing ultrasound versus MRI imaging to prevent liver cancer mortality in people with hepatocellular carcinoma or cirrho…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body. [Phase 1, Phase 2]
Pfizer is testing PF-08634404 as a single-agent and combination therapy for unresectable or advanced hepatocellular carcinoma in a Phase 1/2…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer [Phase 1]
Phase 1 clinical trial evaluating the combination of durvalumab and tremelimumab after radioembolization for unresectable locally advanced h…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous dendritic cell therapy and Prevnar vaccine with immune checkpoint inhibition following high-dose exter…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing [Phase 1]
Phase 1 clinical trial investigating therapeutic drug monitoring-based dosing of atezolizumab across multiple cancers, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer [Phase 1, Phase 2]
A dose-defining study of tirapazamine combined with embolization in liver cancer (hepatocellular carcinoma) is in Phase 1/Phase 2 and curren…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: AI-Assisted Staging and Treatment Decision-Making for Hepatocellular Carcinoma
A clinical trial evaluating AI-assisted staging and treatment decision-making for hepatocellular carcinoma is currently recruiting at Beijin…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Phase 2 Study of WGI-0301 Plus Lenvatinib in Patients With Advanced HCC [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating WGI-0301 in combination with Lenvatinib for advanced hepatocellular …
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CLINICAL_TRIALS other · 2026-04-20Clinical Trial Update: A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors [Phase 1]
Clinical trial update for PF-08046054/SGN-PDL1V in advanced solid tumors shows a Phase 1 study is currently recruiting across multiple indic…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer [Phase 1]
This clinical trial update reports on a Phase 1 study evaluating a three-drug combination of IRX-2, cyclophosphamide, and nivolumab in patie…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Efficacy and Safety Comparison Between PD-1 Inhibitor Combined With Lenvatinib or With Regorafenib For UHCC After Failure of First-line Treatment [NA]
A completed clinical trial comparing a PD-1 inhibitor plus lenvatinib versus a PD-1 inhibitor plus regorafenib in patients with unresectable…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Identification of New Serum Diagnostic Markers of Hepatocellular Carcinoma
A completed clinical trial investigating new serum markers for diagnosing hepatocellular carcinoma (liver cancer).
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Phase II Study of Moderate-dose Hypofractionated RT Combined With Tislelizumab for HCC With Diffuse Tumor Thrombosis [Phase 2]
A Phase II trial testing moderate-dose hypofractionated radiotherapy plus tislelizumab for hepatocellular carcinoma with diffuse tumor throm…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Advanced HCC
This clinical trials update reports on a completed study evaluating transarterial chemoembolization (TACE) in combination with PD-1/PD-L1 in…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Longitudinal Observational Study of the Natural History and Management of Patients With HCC
This document describes a longitudinal observational study evaluating the natural history and management of patients with hepatocellular car…
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CLINICAL_TRIALS other · 2026-04-17Clinical Trial Update: A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of BGB-B2033 alone or with tislelizumab, with or without bevacizumab, in adults with advanced or metastatic solid tumors. Indi…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Denosumab Strategy for Liver Cancer With Bone Metastases [Phase 2]
A Phase 2 clinical trial evaluating denosumab as a strategy for hepatocellular carcinoma with bone metastases. The study is currently not ye…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: The Effects of a Nurse-led TGA-based Pre-rehabilitation Planning on Perioperative Outcomes in Patients With Liver Cancer: Study and Protocol [NA]
A study protocol evaluating a nurse-led, TGA-based pre-rehabilitation planning approach to improve perioperative outcomes in patients with l…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Surgery Plus Systemic Therapy for Liver Cancer With Extrahepatic Metastases [NA]
Tongji Hospital is conducting a clinical trial on surgery plus systemic therapy for hepatocellular carcinoma with extrahepatic metastases; t…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Intermediate HCC
A clinical trial evaluating transarterial chemoembolization (TACE) in combination with PD-1/PD-L1 inhibitors and molecular-targeted therapie…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer [Phase 2]
A Phase 2 study evaluating novel immunomodulators as both monotherapy and in combination with anticancer agents for advanced hepatobiliary c…