Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Durvalumab/Tremelimumab in Neoadjuvant and Adjuvant Setting in Patients With HCC Treated by by Percutaneous Ablation Procedure [Phase 2]
Phase 2 clinical trial evaluating durvalumab plus tremelimumab as neoadjuvant and adjuvant therapy in hepatocellular carcinoma patients unde…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Detection of Plasma DNA Methylation in Peripheral Blood From Patients With Resectable Liver Cancer
Mayo Clinic-sponsored clinical trial update examining plasma DNA methylation in blood from patients with resectable hepatocellular carcinoma…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies [Phase 2]
Phase 2 clinical trial evaluating a PD-1–blocking monoclonal antibody in combination with a metabolic modulator for several solid tumors is …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating RBS2418 in combination with tremelimumab and durvalumab in participants with advanced unresectable hepatoc…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Use of Gender, Age, Alfa-fetoprotein (AFP), and Des-gamma-carboxyprothrombin (PIVKA-II) or GAAD Score in Addition to Ultrasound for Surveillance of People At-risk for Developing Hepatocellular Carcinoma in Asia in Order to Detect Early Liver Cancer [NA]
This clinical trial update describes a study evaluating GAAD score plus AFP/PIVKA-II or ultrasound for surveillance of people at risk for he…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Computer Guided Microwave Liver Ablation [NA]
The clinical trial is evaluating computer-guided microwave liver ablation for hepatocellular carcinoma and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate Patient-Reported Satisfaction, Effectiveness, and Safety of Atezolizumab in Participants Treated in Routine Clinical Practice
This study evaluates patient-reported satisfaction, effectiveness, and safety of atezolizumab when used in routine clinical practice for lun…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma. [Phase 1]
Clinical trial update on a PD-1 mRNA lipid nanoparticle vaccine being tested for advanced hepatocellular carcinoma; Phase 1 and currently re…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion [Phase 2]
Phase 2 trial evaluating proton beam radiotherapy followed by atezolizumab (Tecentriq) and bevacizumab (Avastin) for hepatocellular carcinom…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Annual MRI Versus Biannual US for Surveillance of Hepatocellular Carcinoma in Liver Cirrhosis
A completed clinical trial comparing annual magnetic resonance imaging to biannual ultrasound for hepatocellular carcinoma surveillance in p…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver) [Phase 1, Phase 2]
Hoffmann-La Roche is conducting the MORPHEUS-Liver trial to evaluate the efficacy and safety of multiple immunotherapy-based treatment combi…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Phase Ib/II Trial to Evaluate the Efficacy and Safety of HH-009 for the Treatment of FGF19-positive Advanced or Unresectable HCC [Phase 1, Phase 2]
This clinical trial update describes a Phase Ib/II study evaluating HH-009 for FGF19-positive advanced or unresectable hepatocellular carcin…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: FOG-001 in Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
FOG-001 is being studied in a Phase 1/2 trial across multiple locally advanced or metastatic solid tumors and is currently recruiting; indic…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Multimodal Machine Learning Characterization of Solid Tumors
This ClinicalTrials.gov update describes a multimodal machine learning study to characterize solid tumors, listing prostate cancer, hepatoce…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: LEAF(Liver Tumor dEtection And classiFication AI) [NA]
An update on a Zhejiang University trial evaluating LEAF, an AI system for liver tumor detection and classification in hepatocellular carcin…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012) [Phase 3]
A Phase 3 trial (LEAP-012) evaluating lenvatinib plus pembrolizumab with transarterial chemoembolization in patients with incurable/non-meta…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC [Phase 1, Phase 2]
A Phase 1/2 clinical trial update assessing GNOS-PV02 personalized neoantigen vaccine in combination with INO-9012 and pembrolizumab for adv…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma [NA]
This clinical trial update describes a study evaluating low-dose bevacizumab and atezolizumab in combination with TACE-HAIC for unresectable…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Phase IIa, Single-arm, Open-label Clinical Study to Evaluate the Efficacy, Safety and PK of CVM-1118 in Combination With Sintilimab and TACE in Participants With Incurable/Non-metastatic HCC [Phase 2]
Phase IIa, single-arm, open-label study to evaluate CVM-1118 in combination with sintilimab and TACE for incurable/non-metastatic hepatocell…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models
Prospective validation of LIRIC liver cancer risk models is described, evaluating predictive performance for hepatocellular carcinoma; the s…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Effect of Babao Dan Capsule Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis [NA]
This clinical trial evaluates whether Babao Dan Capsule in combination with antiviral therapy can reduce the incidence of hepatocellular car…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Low-dose Bevacizumab Plus Adebrelimab Combined With Transarterial Chemoembolization Followed by TACE-HAIC [Phase 2]
Phase 2 clinical trial evaluating low-dose bevacizumab plus adebrelimab with transarterial chemoembolization followed by TACE-HAIC for hepat…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: HAIC Combined With Sintilimab Plus Bevacizumab Biosimilar for Advanced Hepatocellular Carcinoma (TASK-03) [Phase 2]
A Phase 2 trial (TASK-03) evaluating hepatic arterial infusion chemotherapy combined with sintilimab and a bevacizumab biosimilar in advance…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Different First-line Immunotherapy for Advancer Hepatocellular Carcinoma: A Prospective Observational Study on Efficacy and Immune Microenvironment
A prospective observational study evaluating different first-line immunotherapies for advanced hepatocellular carcinoma, focusing on efficac…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Platform Trial for Personalized and Adaptive Therapies in Hepatocellular Carcinoma [Phase 2]
This is a Phase 2 platform trial in hepatocellular carcinoma exploring personalized and adaptive therapies. The study is currently recruitin…