Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations [Phase 1]
This Phase 1 trial update evaluates TYRA-430 in hepatocellular carcinoma and FGFR-altered solid tumors, highlighting safety signals and prel…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients [NA]
This clinical trial evaluates liver-directed interventional radiology therapies and hypofractionated image-guided radiation therapy for hepa…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Deep Learning-Based Multidimensional Body Composition Mapping for Outcome Prediction in HCC Patients Undergoing TACE
This clinical trial explores using deep learning-based multidimensional body composition mapping to predict outcomes for hepatocellular carc…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: 15 vs 45 Minute Pringle Maneuver in Liver Cancer Resection: Randomized Noninferiority Trial [NA]
A randomized noninferiority trial comparing 15-minute versus 45-minute Pringle maneuver during liver cancer resection is not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: The Study Collect Clinical Data From the Treatment of Liver Cancer With New Drugs After 2019 and Integrate Biochemical and Pathological Indicators to Analyze Prognostic Outcomes, Including Overall Survival, Progression-free Survival, and Complications.
A clinical trial update collecting data on liver cancer patients treated with pembrolizumab, atezolizumab, or lenvatinib after 2019 and anal…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Interventional AI-Human Collaboration for Liver Tumor Diagnosis [NA]
Completed interventional clinical trial examining an AI–human collaboration approach for diagnosing liver tumors. The study encompasses hepa…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial [Phase 2]
A Phase 2 clinical trial evaluating the combination of atezolizumab and bevacizumab with TACE-HAIC for unresectable advanced hepatocellular …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Sequential Transarterial Chemoembolization (TACE), Stereotactic Body Radiation Therapy (SBRT), and Immune Checkpoint Inhibitors for Unresectable Hepatocellular Carcinoma Treated With Donafenib [Phase 2]
A Phase 2 clinical trial in China is testing sequential transarterial chemoembolization (TACE), stereotactic body radiation therapy (SBRT), …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Sequential TACE-SBRT Combined With Targeted Immunotherapy for Patients With Intermediate to Advanced Liver Cancer
A clinical trial evaluating sequential transarterial chemoembolization (TACE) and stereotactic body radiotherapy (SBRT) in combination with …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Fibroscan Study in HCC [NA]
The document provides an update on a Fibroscan study in hepatocellular carcinoma, including patients scheduled for transarterial chemoemboli…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy [Phase 2]
Phase 2 trial comparing short-stitch versus traditional suture to prevent incisional hernia after open hepatectomy (liver resection); curren…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular Cancer [Phase 2]
Phase 2 trial update evaluating maintenance zanzalintinib plus durvalumab in advanced hepatocellular carcinoma; the study is currently not r…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA) [Phase 2]
Phase 2 trial ZENOBIA evaluating Zanzalintinib in combination with Durvalumab and Tremelimumab for unresectable hepatocellular carcinoma is …
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells [Phase 1]
Phase 1 clinical trial evaluating GPC3-targeted CAR T cells armored with IL-15 and IL-21 for GPC3-positive solid tumors; currently recruitin…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Clinical trial SYNERGY-AI is an AI-based precision oncology matching and registry study sponsored by Massive Bio, currently recruiting acros…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Visugromab, Nivolumab and a Tyrosine Kinase Inhibitor (TKI) Compared to Double Placebo and a TKI in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure [Phase 2]
A Phase 2 clinical trial evaluating Visugromab, Nivolumab, and a Tyrosine Kinase Inhibitor versus double placebo and a TKI in unresectable o…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: FAST (Focused Abbreviated Screening Technique)-MRI Study
The FAST-MRI study, sponsored by Icahn School of Medicine at Mount Sinai, is currently enrolling by invitation and focuses on patients with …
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
This clinical trial update describes a study evaluating detection of tumor cells and tumor DNA in blood, urine, and bone marrow across multi…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Dosimetric Differences and Clinical Significance Analysis Between Body Gamma Knife and VMAT Radiotherapy for Primary Liver Cance
This clinical trial update assesses dosimetric differences between Body Gamma Knife and VMAT radiotherapy for primary liver cancers. It also…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Y-90 Treatment Response Using Transarterial Radioembolization [Phase 2]
Phase 2 clinical trial evaluating response to Yttrium-90 transarterial radioembolization in hepatocellular carcinoma; recruitment is ongoing…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC) [Phase 2]
A Phase 2 study evaluating atezolizumab, bevacizumab, and memantine in hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: [68Ga]Ga-PSMA PET/CT in Hepatocellular Carcinoma: Impact of Multiparametric Dynamic Whole-body Imaging and Kinetic Modeling. [NA]
A clinical trial evaluating Gallium-68 PSMA PET/CT imaging in hepatocellular carcinoma, focusing on multiparametric dynamic whole-body imagi…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: GKL-006 Combined With TACE in Treatment of Unresectable Hepatocellular Carcinoma [Phase 2]
A Phase 2 clinical trial investigating GKL-006 in combination with transarterial chemoembolization (TACE) for unresectable hepatocellular ca…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients [Phase 2]
Phase II multinational trial comparing safety and efficacy of SIRT (Y-90 resin microspheres) followed by atezolizumab plus bevacizumab versu…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers [NA]
A UCSF-led clinical trial is evaluating radiation therapy for metastatic gastrointestinal cancers, and the study is currently recruiting.