Hepatoblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies [Phase 1]
Phase 1 trial at New York Medical College evaluating vorinostat in combination with chemotherapy for relapsed/refractory solid tumors and CN…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial) [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating ensartinib for patients with relapsed or refractory ALK- or ROS1-genomic a…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative
This is a prospective registry and Liver Tumor Research Consortium initiative studying relapsed and refractory hepatoblastoma, currently rec…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells [Phase 1]
Phase 1 pediatric trial of interleukin-15 and interleukin-21 armored glypican-3–specific CAR T cells for solid tumors, including liver-origi…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Biomarkers of Resiliency In Childhood Cancer Surgery
Clinical trial update from Mayo Clinic on biomarkers of resiliency in pediatric cancer surgery, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors [Phase 1]
This is an update on a Phase 1 trial of interleukin-15 armored GPC3-specific CAR-T cells for pediatric solid tumors, with results posted and…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Prospective Multicenter Clinical Study of SCCG Protocol and ctDNA 5hmc in Predicting the Chemotherapy Sensitivity and Monitoring the Recurrence and Metastasis of Hepatoblastoma in Children and Adolescents [Phase 2]
Phase 2 multicenter study evaluating SCCG protocol and ctDNA 5hmc for predicting chemotherapy sensitivity and monitoring recurrence/metastas…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery [Phase 3]
This Phase 3 clinical trial update describes a study evaluating cisplatin-based chemotherapy after surgery for children and young adults wit…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells [Phase 1]
Phase 1 clinical trial evaluating GPC3-targeted CAR T cells armored with IL-15 and IL-21 for GPC3-positive solid tumors; currently recruitin…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors [Phase 1]
Phase 1 study evaluating flavored oral irinotecan VAL-413 (Orotecan) with temozolomide for recurrent pediatric solid tumors is currently rec…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Pucotenlimab Combined With Lenvatinib and Chemotherapy in the Treatment of Advanced, Relapsed/Refractory Hepatoblastoma in Children [NA]
A clinical trial update announcing a study evaluating pucotenlimab in combination with lenvatinib and chemotherapy for advanced, relapsed/re…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Molecular Basis of Pediatric Liver Cancer
University of Pittsburgh sponsors a recruiting study on the molecular basis of pediatric liver cancer, evaluating several liver tumor types …
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers
A French multicenter observational retrospective study aimed at characterizing rare primary liver cancers, currently recruiting, including s…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy [Phase 3]
A Phase 3 multi-institutional trial investigating a modified PHITT strategy for children with newly diagnosed hepatoblastoma, currently recr…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma [Phase 1, Phase 2]
Eureka Therapeutics reports a Phase 1/2 trial recruiting pediatric patients with hepatoblastoma, hepatocellular carcinoma, and related liver…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models
A clinical trial from Xinhua Hospital and Shanghai Jiao Tong University aims to improve diagnosis and grading of pediatric solid tumors usin…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Yttrium-90 (TARE-Y90) in Children, Adolescents, and Young Adults With Liver Tumors
A pediatric trial evaluating Yttrium-90 radioembolization for liver tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families
This update reports the completion of a clinical trial examining the psychosocial experiences of children with rare solid abdominal tumors a…
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Paediatric Hepatic International Tumour Trial [Phase 3]
This is an update on a pediatric Phase 3 international trial evaluating treatments for liver tumors. The study is currently active but not r…
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CLINICAL_TRIALS trial_result · 2024-04-24Clinical Trial Update: Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating palbociclib in relapsed or refractory pediatric tumors with activating alterations in cell cycle ge…