Hepatitis D

• CLINICAL_TRIALS trial_result · 2026-04-17
  Clinical Trial Update: Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver Disease

  This completed study sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) evaluated the response to COV…

• CLINICAL_TRIALS trial_result · 2026-03-31
  Clinical Trial Update: A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide [Phase 3]

  This Phase 3 study is evaluating a combination of Tobevibart and Elebsiran in participants with chronic hepatitis D infection not virologica…

• CLINICAL_TRIALS trial_result · 2026-03-02
  Clinical Trial Update: A Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection [Phase 2, Phase 3]

  This clinical trial update describes a Phase 2/3 study of BJT-778 versus delayed treatment for chronic hepatitis D infection, with the trial…

• CLINICAL_TRIALS trial_result · 2026-02-03
  Clinical Trial Update: Trial to Evaluate the Efficacy, Safety and Pharmacokinetics of RBD1016 in Participants With Chronic Hepatitis D [Phase 2]

  A Phase 2 clinical trial evaluating the efficacy, safety, and pharmacokinetics of RBD1016 in participants with chronic hepatitis D is curren…

• CLINICAL_TRIALS trial_result · 2025-12-04
  Clinical Trial Update: A Study to Assess the Safety, Tolerability and Pharmacokinetics of ABI-6250 in Healthy Participants [Phase 1]

  A Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of ABI-6250 in healthy participants for hepatitis D is reported as…

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• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: Study of Bulevirtide in Participants With Chronic Hepatitis D Infection

  A clinical trial update indicates bulevirtide is being studied for chronic hepatitis D infection, with the study currently active but not re…

• CLINICAL_TRIALS trial_result · 2025-10-14
  Clinical Trial Update: SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection. [Phase 2]

  Phase 2 SOLSTICE trial update sponsored by Vir Biotechnology, evaluating a combination therapy for chronic hepatitis D infection; the study …

• CLINICAL_TRIALS trial_result · 2025-09-18
  Clinical Trial Update: A Multiple-Dose Study of Bulevirtide in Participants With Normal and Impaired Renal Function [Phase 1]

  Phase 1 multiple-dose study of bulevirtide in participants with normal or impaired renal function for chronic hepatitis D infection; results…

• CLINICAL_TRIALS trial_result · 2025-09-15
  Clinical Trial Update: Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)

  The IMPHROVE-D trial reports improvement of portal hypertension in patients with hepatitis D during viral suppression; the study is active b…

• CLINICAL_TRIALS trial_result · 2025-08-11
  Clinical Trial Update: Assessment of Response and Safety of Bulevirtide Treatment in Patients With Chronic Delta Virus Infection

  This clinical trial update summarizes the evaluation of biochemical and virologic response and safety of bulevirtide in patients with chroni…

• CLINICAL_TRIALS trial_result · 2025-07-02
  Clinical Trial Update: The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infection [Phase 1]

  This Phase 1 trial evaluated the safety and preliminary efficacy of sequential Ropeginterferon alfa-2b (P1101) followed by an anti-PD-1 agen…

• CLINICAL_TRIALS trial_result · 2025-04-25
  Clinical Trial Update: Incidence of Viral Hepatitis D Relapses Upon Discontinuation of Bulevirtide in Patients With Chronic Hepatitis D and Negative HDV RNA

  The update reports on the incidence of hepatitis D relapse after discontinuation of bulevirtide in patients with chronic hepatitis D who had…

• CLINICAL_TRIALS trial_result · 2025-01-22
  Clinical Trial Update: Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment [Phase 1]

  Phase 1 pharmacokinetic study evaluating tipranavir/ritonavir, ribavirin, and pegylated interferon in subjects with mild hepatic impairment …

• CLINICAL_TRIALS trial_result · 2024-11-06
  Clinical Trial Update: A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus [Phase 2]

  Phase 2 trial of JNJ-73763989 in people co-infected with hepatitis B and hepatitis D has completed and posted results.

• CLINICAL_TRIALS trial_result · 2024-07-29
  Clinical Trial Update: Study to Assess Efficacy and Safety of Bulevirtide in Combination With Pegylated Interferon Alfa-2a in Participants With Chronic Hepatitis Delta (CHD) [Phase 2]

  Phase 2 trial evaluating bulevirtide in combination with pegylated interferon alfa-2a for chronic hepatitis D has completed and posted resul…

• CLINICAL_TRIALS trial_result · 2024-04-24
  Clinical Trial Update: Study of Hepalatide in Chronic Hepatitis D(CHD) Patients [Phase 2]

  Phase 2 trial update for Hepalatan in chronic hepatitis D shows completed status; no efficacy results provided in snippet.

• CLINICAL_TRIALS trial_result · 2023-05-06
  Clinical Trial Update: Once Daily Dosing of Lonafarnib Co-administered With Ritonavir for Treatment of Chronic Hepatitis D Virus Infection [Phase 3]

  A Phase 3 clinical trial evaluating once-daily lonafarnib with ritonavir for chronic hepatitis D virus infection is ongoing, with status cur…

• CLINICAL_TRIALS trial_result · 2023-02-21
  Clinical Trial Update: Lonafarnib Boosted With Ritonavir With and Without Peginterferon Alfa-2a (PEG IFN-a) in HDV (LOWR-2) [Phase 2]

  A Phase 2 trial evaluating lonafarnib with and without ritonavir, with and without peginterferon alfa-2a, in chronic hepatitis D infection h…

• CLINICAL_TRIALS trial_result · 2023-01-17
  Clinical Trial Update: A Study to Evaluate Pegylated Interferon Lambda Monotherapy in Patients With Chronic Hepatitis Delta Virus Infection [Phase 2]

  Phase 2 trial evaluating pegylated interferon lambda monotherapy for chronic hepatitis delta virus; study completed with results posted.

• CLINICAL_TRIALS trial_result · 2022-12-29
  Clinical Trial Update: A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection [Phase 2]

  Phase 2 trial investigating P1101 plus TAF with or without UDCA in hepatitis D/HBV co-infected patients; status not disclosed.

• CLINICAL_TRIALS trial_result · 2022-11-29
  Clinical Trial Update: Lonafarnib With and Without Ritonavir in HDV (LOWR-1) [Phase 2]

  Phase 2 trial update evaluating lonafarnib with and without ritonavir in chronic Hepatitis D infection has completed with results posted.

• CLINICAL_TRIALS trial_result · 2021-12-01
  Clinical Trial Update: Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon [Phase 2]

  Phase 2 trial evaluating lonafarnib, ritonavir, and lambda interferon for chronic hepatitis D has completed with posted results.

• CLINICAL_TRIALS trial_result · 2021-02-25
  Clinical Trial Update: Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agent [Phase 2]

  Phase 2 trial comparing Myrcludex B plus peginterferon alfa-2a versus peginterferon alfa-2a alone in chronic hepatitis B with delta-agent; r…

• CLINICAL_TRIALS trial_result · 2019-12-30
  Clinical Trial Update: A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D [Phase 2]

  Phase 2 randomized study evaluating three dosing regimens of Myrcludex B with tenofovir versus tenofovir alone for chronic hepatitis D; stud…

• CLINICAL_TRIALS trial_result · 2019-04-12
  Clinical Trial Update: Study of ARC-520 With or Without Other Drugs Used in the Treatment of Chronic Chronic Hepatitis B Virus (HBV) [Phase 2]

  Phase 2 study of ARC-520 for chronic hepatitis B with or without other drugs was terminated; results were posted in 2019.