Hepatitis C
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Armodafinil for Patients Starting Hepatitis C Virus Treatment [Phase 4]
A Phase 4 trial of armodafinil in patients beginning hepatitis C treatment was terminated, with results posted in February 2017.
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Individualized Triple-therapy Using Boceprevir in HIV-positive Patients With Hepatitis C [Phase 4]
Phase 4 study evaluating boceprevir-based triple therapy for HIV-positive patients with chronic hepatitis C has completed, with results post…
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CLINICAL_TRIALS research · 2017-02-06Clinical Trial Update: An Observational/Non-interventional, Study of NS3/4a Protease and NS5A Protein of Hepatitis C Virus in Brazilian Participants With Chronic HCV Infection
This is an observational, non-interventional study conducted in Brazilian participants with chronic hepatitis C infection. It examines the N…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: A Study to Evaluate the Safety and Antiviral Effect of ABT-450/Ritonavir and ABT-530 Coadministered With and Without Ribavirin in Adults With Genotype 3 Hepatitis C (HCV) Infection [Phase 2]
Phase 2 trial evaluating safety and antiviral effect of ABT-450/ritonavir and ABT-530 with and without ribavirin in adults with genotype 3 h…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Ultrasound Method to Measure Fibrosis of the Liver in Children [NA]
Update on a pediatric ultrasound method to measure liver fibrosis; the trial was terminated and results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: A Study of Faldaprevir, Ribavirin and TD-6450 in Participants With Genotype 4 Hepatitis C Virus Infection [Phase 2]
A Phase 2 clinical trial evaluating the combination of faldaprevir, ribavirin, and TD-6450 for hepatitis C virus infection has completed, re…
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Hepatitis B Virus (HBV) Prevention for Homeless at Risk for HBV/Hepatitis C Virus (HCV)/HIV [NA]
The UCLA-sponsored trial evaluating prevention strategies for Hepatitis B among homeless individuals at risk for HBV, Hepatitis C, and HIV h…
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CLINICAL_TRIALS research · 2017-01-30Clinical Trial Update: Assessment of Intrahepatic Hepatitis C Virus (HCV) RNA Levels at the Time of Liver Transplantation
This clinical trial update describes an assessment of intrahepatic hepatitis C virus (HCV) RNA levels at the time of liver transplantation. …
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Safety and Efficacy Study of the Combination Daclatasvir (60 mg), Sofosbuvir (400 mg) and Ribavirin (Weight-based Dosing) for 12 or 16 Weeks in Subjects With Genotype 3 Chronic HCV Infection With or Without Prior Treatment Experience and Advanced Fibrosis or Compensated Cirrhosis [Phase 3]
Phase 3 safety and efficacy study evaluating daclatasvir with sofosbuvir and ribavirin for 12 or 16 weeks in genotype 3 chronic hepatitis C …
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Antiviral & Antifibrotic Liver Therapy in HCV + Drinkers and Non-Drinkers [Phase 2]
Phase 2 trial update evaluating antiviral and antifibrotic liver therapy for hepatitis C in drinkers and non-drinkers.
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CLINICAL_TRIALS research · 2017-01-27Clinical Trial Update: Study Investigating Immunological Effects of Treatment for Chronic Hepatitis C Patients.
The document reports a completed clinical trial investigating the immunological effects of a treatment in patients with chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Clinical Pharmacology Study of MP-424 [Phase 1]
Phase 1 clinical pharmacology study of MP-424 in chronic hepatitis C has been completed.
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: French Cohort of Therapeutic Failure and Resistances in Patients Treated With a Protease Inhibitor (Telaprevir or Boceprevir), Pegylated Interferon and Ribavirin
This clinical trial update discusses outcomes and resistance in a French cohort of chronic hepatitis C patients treated with protease inhibi…
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CLINICAL_TRIALS withdrawal · 2017-01-24Clinical Trial Update: Pioglitazone vs. Placebo in Association With Pegylated Interferon and Ribavirin in HCV Patients With Insulin Resistance [Phase 3]
A Phase 3 trial evaluating pioglitazone added to pegylated interferon and ribavirin in chronic hepatitis C patients with insulin resistance …
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CLINICAL_TRIALS trial_result · 2017-01-23Clinical Trial Update: The Individualized Management With Pegylated-interferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Offering Viral Eradication: A Study of Pegylated-interferon Alfa-2a Plus Ribavirin in Participants With Chronic Hepatitis C (CHC) Non-genotype 2/3 (IMPROVE) [Phase 3]
Phase 3 trial evaluating pegylated interferon alfa-2a plus ribavirin for chronic hepatitis C in non-genotype 2/3 patients; the study complet…
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CLINICAL_TRIALS trial_result · 2017-01-23Clinical Trial Update: EDP-494-001: A Study of EDP-494 in Healthy Subjects and Hepatitis C Patients [Phase 1]
This clinical trial update reports on a Phase 1 study of EDP-494 in healthy subjects and Hepatitis C patients. The trial status is completed…
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CLINICAL_TRIALS research · 2017-01-23Clinical Trial Update: Orange Juice Consumption in Patients With Hepatitis C [NA]
A completed clinical trial evaluated orange juice consumption in patients with hepatitis C.
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: A Study to Assess the Efficacy and Safety of the Combination of Simeprevir and Daclatasvir in Chronic Hepatitis C Genotype 1b-Infected Participants [Phase 2]
Phase 2 trial evaluating the efficacy and safety of the combination of Simeprevir and Daclatasvir in adults with chronic hepatitis C genotyp…
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CLINICAL_TRIALS research · 2017-01-20Clinical Trial Update: Comparison of OraQuick HCV Rapid Antibody Test and Standard Serologic Screening for Hepatitis C: Validity, Acceptability and Impact on Linkage to Care [NA]
A terminated clinical trial comparing the OraQuick HCV Rapid Antibody Test with standard serologic screening to assess validity, acceptabili…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Grazoprevir (MK-5172) and Elbasvir (MK-8742) Combination for Chronic Hepatitis C Virus (HCV) Genotypes 1, 4, and 6 (MK-5172-065) [Phase 3]
Phase 3 trial of Grazoprevir and Elbasvir combination for chronic hepatitis C genotypes 1, 4, and 6 completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: To Evaluate the Safety and Efficacy of Sofosbuvir and Ribavirin in Patients With HCV (Genotype 3) Related Decompensated Cirrhosis [NA]
A clinical trial evaluating the safety and efficacy of Sofosbuvir plus Ribavirin in patients with genotype 3 hepatitis C-related decompensat…
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CLINICAL_TRIALS trial_result · 2017-01-16Clinical Trial Update: Alisporivir (Deb025) and Boceprevir Triple Therapies in African American Participants Not Previously Treated for Chronic Hepatitis C Genotype 1 [Phase 3]
A Phase 3 trial evaluating alisporivir (Deb025) combined with boceprevir in African American patients with chronic hepatitis C genotype 1 wa…
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CLINICAL_TRIALS trial_result · 2017-01-16Clinical Trial Update: Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1 [NA]
This clinical trial update reports a study designed to bridge active heroin users to hepatitis C treatment using buprenorphine. The trial st…
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CLINICAL_TRIALS safety_alert · 2017-01-13Clinical Trial Update: Telaprevir Exposure and Severe Anemia in HCV Infected Patients Treated by Tri-therapy
Clinical trial update notes exposure to telaprevir associated with severe anemia in hepatitis C patients treated with triple therapy; the st…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: HIV and HCV Intervention In Drug Treatment Settings - 1 [Phase 3]
Phase 3 trial update on HIV and Hepatitis C interventions in drug-treatment settings, focusing on behavior therapy; the study status is comp…