Hepatitis C
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Sign up freeTop drugs studied for this disease
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FDA approval · 2018-08-06FDA Approved: MAVYRET — Supplemental Application (AbbVie Inc.)
FDA approved a supplemental application for MAVYRET (glecaprevir and pibrentasvir) submitted by AbbVie. The action approves a supplemental c…
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Efficacy and Safety of Uprifosbuvir (MK-3682) With Ruzasvir (MK-8408) in Adults With Chronic Hepatitis C Genotype 1, 2, 3, 4, 5 or 6 Infection (MK-3682-035) [Phase 2]
Phase 2 trial update on Uprifosbuvir with Ruzasvir in chronic hepatitis C showing terminated status with posted results.
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EMA withdrawal · 2018-07-31EMA Withdrawn: Victrelis (Boceprevir) — Merck Sharp Dohme Ltd
EMA has withdrawn Victrelis (boceprevir) from the market in the EU.
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: A First Time in Human Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single & Repeat Escalating Doses of GSK2878175 in Healthy Subjects [Phase 1]
This is a first-in-human Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of single and repeat escalating doses of GS…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of Repeat Doses of GSK2878175 in Subjects With Chronic Hepatitis C. [Phase 1]
Phase 1 study of repeat-dose GSK2878175 in chronic hepatitis C completed; assesses safety, pharmacokinetics, and antiviral activity.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Japanese Adults With Chronic Hepatitis C Virus Infection [Phase 3]
Phase 3 clinical trial evaluating ABT-493/ABT-530 in Japanese adults with chronic hepatitis C virus infection has completed with posted resu…
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Impact of Sustained Virologic Response on Glycemic Control Among Diabetic Patients With Hepatitis C Virus Related Liver Disease
This clinical trial update investigates whether achieving sustained virologic response to hepatitis C treatment improves glycemic control in…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
This completed pediatric trial from Baylor College of Medicine evaluated non-invasive biomarkers to detect liver fibrosis in children with v…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: The Safety and Efficacy of Daclatasvir and Asunaprevir With Chronic HCV Genotype 1b Infection and Chronic Renal Failure [Phase 4]
Phase 4 trial evaluating the safety and efficacy of Daclatasvir and Asunaprevir in hepatitis C genotype 1b patients with chronic renal failu…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination in Participants With Chronic Hepatitis C Virus Infection [Phase 3]
A Phase 3 trial update on the efficacy and safety of the Sofosbuvir/Velpatasvir fixed-dose combination for chronic hepatitis C virus infecti…
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C [Phase 3]
This Clinical Trial Update describes a Phase 3 open-label study of Algeron (cepeginterferon alfa-2b) for treatment-naive chronic hepatitis C…
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CLINICAL_TRIALS research · 2018-07-16Clinical Trial Update: Prevalence of Hepatitis c Virus Infection Among Rheumatological Patients
A completed study assessing how common hepatitis C infection is among patients with rheumatologic conditions.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Multidisciplinary Support Program in Chronic Hepatitis C
A completed clinical trial evaluating a multidisciplinary support program for chronic hepatitis C; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Cerebral Effects of Pegylated Interferon in Hepatitis C Positive Subjects
A completed clinical trial evaluated the cerebral effects of pegylated interferon in hepatitis C patients, and the results have been posted.…
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Clinical Performance Evaluation of DxN HCV Assay
A clinical trial evaluating the performance of Beckman Coulter's DxN HCV assay for Hepatitis C was terminated before completion.
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir With Sofosbuvir With or Without Ribavirin in Adults With Chronic Hepatitis C Virus Infection [Phase 2]
Phase 2 trial evaluating Ombitasvir/ABT-450/Ritonavir with Sofosbuvir with or without Ribavirin for chronic hepatitis C virus infection has …
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CLINICAL_TRIALS research · 2018-07-06Clinical Trial Update: Very Rapid and Rapid Virological Response as Predictors of Response of HCV Tretment
This clinical trial update investigates whether very rapid virological response (vRVR) and rapid virological response (RVR) can predict trea…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 or 24 Weeks in Participants With Chronic Genotype 1 or 2 Hepatitis C Virus Infection Who Have Previously Failed a Direct-Acting Antiviral-Containing Regimen [Phase 3]
Phase 3 study evaluating sofosbuvir/velpatasvir with ribavirin for 12 or 24 weeks in chronic hepatitis C genotype 1 or 2 patients who failed…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Virus (HCV) Genotype (GT) 3, GT4, GT5, and GT6 Infection (MK-3682-012) [Phase 2]
Phase 2 trial evaluating Grazoprevir with Uprifosbuvir with Elbasvir or Ruzasvir for chronic Hepatitis C across genotypes 3-6; study complet…
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CLINICAL_TRIALS research · 2018-06-29Clinical Trial Update: Safety of Sofosbuvir ,Daclatasvir in HCV Patients and RAVS in Resistent and Relapsed Cases
Clinical trial update evaluating the safety of the Sofosbuvir and Daclatasvir combination in hepatitis C patients, including resistant and r…
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: A Study to Evaluate the Pharmacokinetics and Safety of ASC16 Tablets in Healthy Volunteers in China [Phase 1]
A Phase 1 pharmacokinetics and safety study of ASC16 tablets in healthy volunteers in China has completed.
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FDA approval · 2018-06-28FDA Approved: ZEPATIER — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for ZEPATIER (elbasvir and grazoprevir) from Merck Sharp & Dohme LLC.
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: Crowdsourcing to Promote HBV and HCV Testing in China [NA]
The UNC-Chapel Hill-sponsored trial NCT03482388, a crowdsourcing initiative to promote HBV and HCV testing in China, has completed.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: A Study to Evaluate the Safety and Effect of Treatment With Experimental Antiviral Drugs in Combination With Peginterferon Alpha-2a and Ribavirin in People With Hepatitis C Virus Who Did Not Respond to Treatment in a Previous AbbVie/Abbott Combination Study [Phase 2]
Phase 2 study evaluating the safety and antiviral effect of experimental drugs in combination with peginterferon alfa-2a and ribavirin in pe…
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CLINICAL_TRIALS research · 2018-06-11Clinical Trial Update: Recurrence Rate of Hepatocellular Carcinoma After Treatment of Chronic Hepatits C Patients With Direct Acting Antivirals: Randomized Controlled Phase 3 Trial [Phase 3]
A Phase 3 randomized trial is evaluating recurrence of hepatocellular carcinoma in chronic hepatitis C patients treated with direct-acting a…