Hepatitis C
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients [Phase 2]
Phase 2 trial evaluating TG-2349 in combination with DAG181 (± ribavirin) for efficacy and safety in hepatitis C genotype 1 non-cirrhotic pa…
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF) [Phase 4]
Phase 4 trial evaluating how Ledipasvir/Sofosbuvir affects the pharmacokinetics and renal safety of Tenofovir Alafenamide in patients with h…
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CLINICAL_TRIALS trial_result · 2021-02-05Clinical Trial Update: Open Label Study of the Efficacy and Safety of MBL-HCV1 in Combination With Oral Direct-Acting Antivirals in Patients Undergoing Liver Transplantation for Hepatitis C [Phase 2]
Phase 2 open-label trial of MBL-HCV1 with direct-acting antivirals in liver transplant patients with hepatitis C was terminated; results pos…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients [Phase 3]
Phase III trial evaluating TG-2349 in combination with DAG181 and RBV for chronic hepatitis C virus genotype 1 patients in non-cirrhotic sta…
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant [Phase 4]
Phase 4 trial update on sofosbuvir-based direct-acting antiviral therapy for HIV/HCV coinfected patients before or after liver transplant; s…
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CLINICAL_TRIALS withdrawal · 2021-01-29Clinical Trial Update: Efficacy and Safety of Boceprevir in Combination With Peginterferon Alfa-2b Plus Ribavirin in Pediatric Subjects With Chronic Hepatitis C Genotype 1 (P08034) [Phase 3]
Phase 3 pediatric trial of boceprevir with peginterferon alfa-2b plus ribavirin for chronic hepatitis C genotype 1 was withdrawn.
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EMA withdrawal · 2021-01-22EMA Withdrawn: ViraferonPeg (peginterferon alfa-2b) — Merck Sharp Dohme Ltd
EMA has withdrawn ViraferonPeg (peginterferon alfa-2b) by Merck Sharp & Dohme Ltd for chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO [Phase 4]
Phase 4 real-world study assessing genotype 1 chronic hepatitis C treatment and real-world SVR and patient-reported outcomes.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Strategic Transformation of the Market of HCV Treatments [Phase 2, Phase 3]
A clinical trial update describing a strategic transformation in the market for hepatitis C treatments across Phase 2 and Phase 3 stages.
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: VBMI to Increase Treatment Completion With MK-MK-5172/MK-8742 Among Veterans With Active Substance Use Disorders Genotype 1 Chronic Hepatitis C [NA]
Clinical trial update related to MK-MK-5172/MK-8742 aiming to increase treatment completion among veterans with active substance use disorde…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Efficacy of All-Oral Anti-Viral Therapy for Symptomatic Hepatitis C Virus Infection-Related Cryoglobulinemia [Phase 2, Phase 3]
Phase 2/3 trial update on an all-oral antiviral therapy for symptomatic hepatitis C virus–related cryoglobulinemia; study completed with res…
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CLINICAL_TRIALS trial_result · 2020-12-16Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Velpatasvir in Participants With Chronic HCV Infection [Phase 1]
Phase 1 study evaluating velpatasvir in chronic hepatitis C patients; completed with results posted.
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CLINICAL_TRIALS withdrawal · 2020-12-07Clinical Trial Update: Bioequivalence Study of Crushed Sofosbuvir/Velpatasvir Compared to the Whole Tablet [Phase 4]
A Phase 4 bioequivalence study comparing crushed sofosbuvir/velpatasvir to the whole tablet was withdrawn.
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: Study of Oral Treatments for Hepatitis C [Phase 4]
A Phase 4 clinical trial update on oral treatments for chronic hepatitis C has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-11-20Clinical Trial Update: Eight Weeks of Elbasvir/Grazoprevir in the Treatment of HCV Genotype 4 [Phase 3]
Phase 3 trial update evaluating eight weeks of elbasvir/grazoprevir for chronic hepatitis C genotype 4 has completed.
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CLINICAL_TRIALS trial_result · 2020-11-16Clinical Trial Update: Study to Evaluate the Pharmacokinetics of Velpatasvir in Participants With Normal Renal Function and Severe Renal Impairment [Phase 1]
Phase 1 pharmacokinetics study evaluating velpatasvir in participants with normal renal function and severe renal impairment has completed.
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CLINICAL_TRIALS research · 2020-11-16Clinical Trial Update: deLIVER: Direct Acting Antiviral Effects on the Liver [Phase 4]
A Phase 4 trial update evaluating direct-acting antivirals' effects on the liver in patients with hepatitis C coinfection and liver disease;…
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CLINICAL_TRIALS trial_result · 2020-11-12Clinical Trial Update: Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care [Phase 4]
Phase 4 trial comparing methadone or syringe exchange–assisted therapy to standard of care for Hepatitis C treatment in people who inject dr…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Efficacy and Safety of Ravidasvir + Danoprevir/r 12-week Oral Therapy in Treatment-Naive Non Cirrhotic G1 CHC Taiwan [Phase 2]
Phase 2 trial evaluating Ravidasvir plus Danoprevir/r for 12 weeks in treatment-naive non-cirrhotic genotype 1 chronic hepatitis C patients …
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Effect of Direct-acting Antiviral Drugs on Erectile Function [Phase 3]
Phase 3 clinical trial investigating the effect of direct-acting antivirals on erectile function in Hepatitis C patients.
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Pilot Treatment as Prevention for HCV Among Persons Who Actively Inject Drugs [Phase 4]
Phase 4 clinical trial update on pilot treatment as prevention for hepatitis C among active injection drug users; study completed.
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CLINICAL_TRIALS research · 2020-10-19Clinical Trial Update: Association of Hepatitis C Virus With Breast Cancer
Clinical trial update investigating the association between Hepatitis C virus infection and breast cancer; study completed with results post…
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir in Adolescents and Children With Chronic HCV Infection [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of Sofosbuvir/Velpatasvir in adolescents and children with chronic hepatitis C infection …
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CLINICAL_TRIALS trial_result · 2020-09-21Clinical Trial Update: A Study to Assess Resistance and Durability of Response to ABT-493 and/or ABT-530 [Phase 2, Phase 3]
Phase 2/3 study evaluating resistance and durability of response for ABT-493 and ABT-530 in Hepatitis C has completed with results posted.
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CLINICAL_TRIALS withdrawal · 2020-09-14Clinical Trial Update: HepATocellular Cancer Hcv Therapy Study [Phase 3]
Phase 3 trial for hepatocellular carcinoma/HCV therapy has been withdrawn.