Hepatitis C
📧 Sign up to get email alerts when something new happens for Hepatitis C.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in China [Phase 4]
Phase 4 trial evaluating a 12-week SOF/VEL regimen with prophylactic TAF in treatment-naïve genotype 1-6 HCV/HBV coinfected adults, with or …
-
CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV [NA]
Clinical trial update on interventions for heavy drinking among patients with HIV and HCV, with completed status and results posted.
-
CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection [Phase 4]
Phase 4 trial update monitoring Sofosbuvir/Velpatasvir (SOF/VEL) in treatment-naïve hepatitis C patients with active infection; results comp…
-
CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Intra-Individual Reproducibility of the Non-Invasive Assessment of the Portal Circulation [NA]
Completed clinical trial assessing intra-individual reproducibility of non-invasive portal circulation assessment using HepQuant technology;…
-
CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Pediatric Subjects With Genotypes 1-6 Chronic Hepatitis C Virus (HCV) Infection [Phase 2, Phase 3]
Phase 2/3 pediatric trial evaluating pharmacokinetics, safety, and efficacy of Glecaprevir/Pibrentasvir in children with genotypes 1–6 chron…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: Trial for the Treatment of Acute Hepatitis C for 8 Weeks With Sofosbuvir/Velpatasvir [Phase 2]
A Phase 2 trial evaluating an 8-week course of sofosbuvir/velpatasvir for acute hepatitis C has completed.
-
FDA approval · 2021-06-10FDA Approved: MAVYRET — Original Application (AbbVie Inc.)
FDA approved MAVYRET (glecaprevir and pibrentasvir) from AbbVie in its original application for the treatment of hepatitis C virus infection…
-
FDA approval · 2021-06-10FDA Approved: EPCLUSA — Original Application (Gilead Sciences, Inc.)
FDA approved Epclusa (velpatasvir/sofosbuvir) in an original application for the treatment of chronic hepatitis C virus infection.
-
FDA approval · 2021-06-10FDA Approved: MAVYRET — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for MAVYRET (glecaprevir and pibrentasvir) submitted by AbbVie, potentially updating its labelin…
-
FDA approval · 2021-06-10FDA Approved: EPCLUSA — Supplemental Application (Gilead Sciences, Inc.)
FDA approved a supplemental application for EPCLUSA (velpatasvir/sofosbuvir) from Gilead Sciences, Inc.
-
EMA withdrawal · 2021-06-03EMA Withdrawn: PegIntron (peginterferon alfa-2b) — Merck Sharp & Dohme B.V.
EMA withdrew PegIntron (peginterferon alfa-2b) from the market for chronic hepatitis C.
-
CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C] [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial evaluated pegylated interferon in combination with direct-acting antivirals for hepatitis C, with results …
-
CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic [Phase 4]
Pilot Phase 4 trial evaluating treatment for hepatitis C at a psychiatrist-staffed outpatient addiction clinic completed with results posted…
-
CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: Multi-center Study to Transplant Hepatitis-C Infected Kidneys [Phase 4]
A multi-center Phase 4 trial evaluated transplanting kidneys from hepatitis C-infected donors into recipients with renal failure, with resul…
-
CLINICAL_TRIALS withdrawal · 2021-05-06Clinical Trial Update: Elimination of HCV Through Linkage and In Prison Treatment of Incarcerated Populations (ECLIPSE) [Phase 4]
Phase 4 trial for HCV infection titled ECLIPSE has been withdrawn.
-
CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: Study of CDI-31244 in Combination With Sofosbuvir (SOF) and Velpatasvir (VEL) [Phase 2]
Phase 2 clinical trial update for CDI-31244 in combination with Sofosbuvir and Velpatasvir in chronic hepatitis C has completed with results…
-
CLINICAL_TRIALS trial_result · 2021-04-23Clinical Trial Update: Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis [Phase 2, Phase 3]
A randomized placebo-controlled trial evaluating safety and efficacy of silymarin in acute viral hepatitis was terminated after Phase 2/3.
-
CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: Evaluation of Daclatasvir (DCV) in Combination With Sofosbuvir (SOF) in Children With Chronic Hepatitis C (CHC) Infection [Phase 2]
Phase 2 trial evaluating daclatasvir plus sofosbuvir in children with chronic hepatitis C was terminated; results were posted in 2021.
-
CLINICAL_TRIALS trial_result · 2021-04-15Clinical Trial Update: Directly Observed Therapy for HCV in Chennai, India [Phase 2]
Phase 2 clinical trial update on directly observed therapy for chronic hepatitis C in Chennai, India; completed with results posted in 2021.
-
CLINICAL_TRIALS trial_result · 2021-04-06Clinical Trial Update: Safety of Sofosbuvir in People With Advanced Kidney Failure [Phase 3]
A Phase 3 clinical trial update assessing the safety of Sofosbuvir in people with advanced kidney failure and chronic hepatitis C has comple…
-
CLINICAL_TRIALS trial_result · 2021-03-23Clinical Trial Update: Efficacy and Safety of Danoprevir/r + PR 12week Triple Therapy in Treatment Naive Non-Cirrhotic G1 CHC China III [Phase 3]
Phase 3 trial update on danoprevir/r plus PR 12-week triple therapy in treatment-naive non-cirrhotic genotype 1 chronic hepatitis C showed c…
-
CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Drug Interaction Potential Between Dolutegravir and Simeprevir in HIV/HCV Seronegative Volunteers [NA]
A completed clinical trial assessing the interaction potential between dolutegravir and simeprevir in HIV/HCV seronegative volunteers.
-
CLINICAL_TRIALS trial_result · 2021-03-16Clinical Trial Update: Grazoprevir/Elbasvir for Genotype 1b Chronic Hepatitis C After Liver or Kidney Transplantation [Phase 4]
Phase 4 trial update on grazoprevir/elbasvir for genotype 1b chronic hepatitis C after liver or kidney transplantation; study terminated.
-
CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant [Phase 4]
Phase 4 trial update evaluating antiviral therapy to prevent de novo hepatitis C infection after liver or kidney transplant; study completed…
-
CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Proof of Concept Study to Determine the Safety and Antiviral Effect of BZF961 With or Without Ritonavir Boosting in Hepatitis C Virus Infected Patients [Phase 1, Phase 2]
A phase 1/2 proof-of-concept study evaluating the safety and antiviral effect of BZF961 with or without ritonavir boosting in hepatitis C pa…