Hemorrhagic Shock
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Biological and Clinical Relevance of Quantra Viscoelastic Hemostatic Assay in Hemorrhagic Cardiac Surgery
This completed clinical trial assesses the biological and clinical relevance of the Quantra viscoelastic hemostatic assay in patients with h…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries.
This clinical trial update describes a study on delaying fluid administration in hemorrhagic shock after severe injuries; the trial is not y…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children [Phase 3]
Phase 3 pediatric trial evaluating massive transfusion for life-threatening hemorrhage after trauma; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial [Phase 3]
A Phase 3 trial evaluating Type O Whole Blood and the impact of donor age during prehospital resuscitation in hemorrhagic shock and traumati…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs [NA]
A clinical trial from the University of Sao Paulo is evaluating prehospital tourniquet models for arterial occlusion in upper and lower limb…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam [NA]
The REVIVE trial evaluating an in-vivo expandable foam to reduce exsanguination is currently recruiting for hemorrhagic shock and trauma ind…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Trauma Resuscitation With Low-Titer Group O Whole Blood or Products [Phase 3]
Phase 3 trial update on trauma resuscitation using low-titer Group O whole blood or related products in patients with wounds, injuries, and …
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Optimization Strategies for Blood Transfusion Protocols in the Emergency Treatment of Hemorrhagic Shock [Phase 3]
Phase 3 clinical trial update on optimizing blood transfusion protocols for emergency treatment of hemorrhagic shock, including upper gastro…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients [Phase 3]
A Phase 3 trial comparing low-titer O-positive whole blood to component therapy for emergent transfusion in trauma patients has completed, w…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Low Dose of Norepinephrine Within 24-Hour Mortality in Traumatic Patient With Hemorrhagic Shock [NA]
A completed clinical trial from Tanta University evaluated the impact of low-dose norepinephrine within 24 hours on mortality in patients wi…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Early Norepinephrine in Trauma Patients With Hemorrhagic Shock [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study of early norepinephrine use in trauma patients with hemorrhagic shock. The trial is curr…
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CLINICAL_TRIALS withdrawal · 2025-05-09Clinical Trial Update: Resuscitative Endovascular Balloon Occlusion of the Aorta in Haemorrhagic Shock
The trial NCT05941572 evaluating resuscitative endovascular balloon occlusion of the aorta (REBOA) for hemorrhagic shock in trauma has been …
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Whole Blood in Trauma Patients With Hemorrhagic Shock [Phase 3]
Phase 3 clinical trial evaluating the use of whole blood in trauma patients with hemorrhagic shock is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Prospective Validation of the SHOCKMATRIX Hemorrhage Predictive Model
This clinical trial update reports prospective validation of the SHOCKMATRIX hemorrhage predictive model in patients with traumatic shock an…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: The AT-REBOA Target Trial
Clinical trial update for the AT-REBOA Target Trial (NCT06312436) from the Medical University of Graz indicates the trial has completed enro…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Cold Stored Platelet in Hemorrhagic Shock [Phase 2]
Phase 2 trial evaluating cold stored platelets for hemorrhagic shock in trauma has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Feasibility of Evaluating XSTAT Use in the Prehospital Setting [NA]
Terminated feasibility trial evaluating XSTAT for prehospital management of hemorrhagic shock due to penetrating injuries. Results were post…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Prehospital Management of Hypotensive Trauma in HEMS
This ClinicalTrials.gov study NCT04760977 is evaluating prehospital management of hypotensive trauma in helicopter EMS and is currently recr…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: California Prehospital and In Hospital Antifibrinolytic Therapy Via TXA [Phase 3]
Phase 3 trial evaluating tranexamic acid for prehospital and in-hospital antifibrinolytic therapy in hemorrhagic shock and trauma has comple…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Infusion of Prostacyclin vs Placebo for 72-hours in Trauma Patients With Haemorrhagic Shock Suffering From Organ Failure [Phase 2]
Phase 2 trial comparing a prostacyclin infusion to placebo over 72 hours in trauma patients with hemorrhagic shock and multi-organ dysfuncti…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Shock, Whole Blood, and Assessment of TBI S.W.A.T. (LITES TO 2)
A completed clinical trial evaluating shock treatment using whole blood in patients with hemorrhagic shock and traumatic brain injury; resul…
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage [Phase 3]
Phase 3 trial update assessing transfusion of red blood cells, tranexamic acid, and fibrinogen concentrate for severe trauma hemorrhage has …
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CLINICAL_TRIALS withdrawal · 2023-05-08Clinical Trial Update: Study Using Plasma for Patients Requiring Emergency Surgery [Phase 4]
Phase 4 trial using plasma for patients requiring emergency surgery was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-10-06Clinical Trial Update: Pragmatic Prehospital Group O Whole Blood Early Resuscitation Trial [Phase 3]
Phase 3 pragmatic trial on early resuscitation with group O whole blood for hemorrhagic shock has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: Resuscitative Endocrinology: Single-dose Clinical Uses for Estrogen-Traumatic Hemorrhagic Shock (RESCUE - Shock) [Phase 2]
Phase 2 trial update for RESCUE - Shock evaluating a single-dose estrogen-based resuscitative approach in hemorrhagic shock; study completed…