Hemorrhage
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EMA approval · 2026-04-23EMA Authorised: Praxbind (idarucizumab) — Boehringer Ingelheim International GmbH
EMA authorised Praxbind (idarucizumab) for hemorrhage. Boehringer Ingelheim International GmbH is the marketing authorisation holder; decisi…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Retrospective Study on Characteristics and Outcomes in Hospitalised Patients Treated With Ondexxya
A completed retrospective study evaluates characteristics and outcomes in hospitalized patients treated with Ondexxya (andexanet alfa) to re…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial [Phase 2]
A Phase 2 clinical trial (CAVALIER) evaluating calcium and vasopressin for trauma with hemorrhage, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Obsidio™ Conformable Embolic Registry
The Obsidio Conformable Embolic Registry trial sponsored by Boston Scientific has completed.
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: RE-BLEED: A Digital Platform for Identifying Bleeding Patients - a Feasibility Study
This document reports on a completed feasibility study of RE-BLEED, a digital platform designed to identify bleeding patients. The study cov…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study [Phase 3]
Phase 3 pediatric trial evaluating tranexamic acid for traumatic brain injury and related hemorrhagic injuries in children; status is NOT_YE…
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EMA safety_alert · 2025-10-31Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 27 - 30 October 2025
The EMA's Pharmacovigilance Risk Assessment Committee (PRAC) agreed to issue a safety communication to healthcare professionals about inject…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM)
A clinical trial registry entry for a study comparing traditional versus newer technology hemodynamic monitors during craniosynostosis surge…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: the Use of Tranexamic Acid to Prevent the Bleeding in Bariatric Surgery [Phase 4]
This document summarizes a Phase 4 clinical trial evaluating tranexamic acid to prevent bleeding in bariatric surgery that has completed.
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Ascending Dose Study of FrontlineODP™ Spray Dried Plasma [Phase 1]
This document reports the completion of a Phase 1 ascending-dose trial of FrontlineODP Spray Dried Plasma by Velico Medical. The trial studi…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Life-saving Treatment With Dry-plasma for Massive Bleeding in an Pre-hospital Setting [Phase 4]
Phase 4 trial update on pre-hospital use of dry-plasma to manage massive bleeding; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients
A pediatric clinical trial is examining the effectiveness of the pressure recording analytical method to predict fluid responsiveness in hyp…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Pre-hospital Ventilation Clinical Study
Zoll Medical Corporation reports an ongoing pre-hospital ventilation trial that is currently enrolling by invitation for patients with sepsi…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen
Completed clinical trial evaluating the incidence of trauma-induced coagulopathy in patients who received prehospital fibrinogen.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Transfusion Using Stored Whole Blood
The UCLA-led clinical trial evaluating transfusion with stored whole blood has completed. It targeted trauma, hemorrhage and coagulopathy.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure
A completed clinical trial evaluated the impact of renal replacement therapy on the coagulation profile of patients with acute renal failure…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Goal-directed vs. Empirical Tranexamic Acid Administrationin Cardiovascular Surgery [NA]
A clinical trial update reports ongoing recruitment for comparing goal-directed versus empirical tranexamic acid use in cardiovascular surge…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Feasibility of Evaluating XSTAT Use in the Prehospital Setting [NA]
Terminated feasibility trial evaluating XSTAT for prehospital management of hemorrhagic shock due to penetrating injuries. Results were post…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Pharmacogenomics of Warfarin in Hispanics and Latinos
A pharmacogenomics study evaluating how genetic factors influence warfarin response in Hispanic and Latino populations; the trial is current…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Trauma Study: Early Warning of Progression Toward Hemodynamic Deterioration After Trauma [NA]
Clinical trial update for a trauma study evaluating early warning of progression toward hemodynamic deterioration after trauma. The trial st…
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CLINICAL_TRIALS trial_result · 2023-09-08Clinical Trial Update: The EVARREST® Paediatric Mild/Moderate Liver and Soft Tissue Bleeding Study [Phase 3]
Phase 3 trial update for EVARREST in pediatric liver and soft tissue bleeding completed, with posted results.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients [Phase 1, Phase 2]
Clinical trial update on extended cold-stored apheresis platelets in cardiac surgery patients across Phase 1/2.
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal [Phase 4]
A Phase 4 trial compared fixed versus variable dosing of 4-factor prothrombin complex concentrate for emergent reversal of warfarin in patie…
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CLINICAL_TRIALS trial_result · 2023-01-27Clinical Trial Update: Pre-hospital Anti-fibrinolytics for Traumatic Coagulopathy and Haemorrhage (The PATCH Study) [Phase 3]
Phase 3 clinical trial update on pre-hospital anti-fibrinolytics for traumatic coagulopathy and hemorrhage (The PATCH Study) completed.
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CLINICAL_TRIALS trial_result · 2022-11-08Clinical Trial Update: Early Administration of Prothrombin Concentrate Complex in Patients With Acute Hemorrhage Following Severe Trauma [Phase 3]
Phase 3 trial evaluating early administration of Prothrombin Concentrate Complex in patients with acute hemorrhage after severe trauma has c…