Hemolytic Uremic Syndrome
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Efficacy of INM004 in Children With STEC-HUS [Phase 3]
Phase 3 trial evaluating INM004 for efficacy in children with Shiga toxin-producing E. coli-associated Hemolytic-Uremic Syndrome is currentl…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium
This entry notes that a prospective study evaluating the role of complement-related thrombotic microangiopathy on the endothelium is current…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Prevalence of Hemolytic Uremic Syndrome (HUS) in Pediatrics
The trial update announces a pediatric prevalence study of Hemolytic Uremic Syndrome sponsored by Assiut University, which is not yet recrui…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection [NA]
Clinical trial update indicating hyperhydration is being studied in children with Shiga toxin-producing Escherichia coli infection, with rec…
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: A Study to Assess Safety, Efficacy, and Pharmacokinetics of INM004 in Pediatric Patients With STEC-HUS [Phase 2]
Phase 2 study assessing safety, efficacy, and pharmacokinetics of INM004 in pediatric patients with STEC-HUS has completed.
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUS [Phase 2, Phase 3]
Phase 2/3 trial evaluating INM004 for prevention of hemolytic uremic syndrome in STEC-positive pediatric patients was terminated.
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CLINICAL_TRIALS trial_result · 2021-01-13Clinical Trial Update: Erythropoietin in Hemolytic Uremic Syndrome [Phase 4]
Phase 4 trial update on erythropoietin use for Hemolytic Uremic Syndrome and anemia has completed.
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CLINICAL_TRIALS trial_result · 2019-07-12Clinical Trial Update: Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU [Phase 3]
A Phase 3 clinical trial evaluating eculizumab for Shiga-toxin related Hemolytic Uremic Syndrome in pediatric patients has completed.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic Syndrome [Phase 3]
A Phase III randomized trial evaluating SYNSORB Pk for E. coli-associated Hemolytic Uremic Syndrome in children was terminated.
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CLINICAL_TRIALS trial_result · 2013-09-04Clinical Trial Update: Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects
Completed clinical trial from Zurich examining hemolytic-uremic syndrome in children, with a focus on clinical features, cognitive outcomes,…
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CLINICAL_TRIALS research · 2013-06-19Clinical Trial Update: International Registry and Biorepository for TMA(Thrombotic Microangiopathy)
The international registry and biorepository study for thrombotic microangiopathy, including hemolytic uremic syndrome and thrombotic thromb…
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CLINICAL_TRIALS withdrawal · 2013-04-17Clinical Trial Update: The Plasma Large-Volume Exchange RCT [Phase 3]
A Phase 3 randomized trial of plasma exchange for thrombotic thrombocytopenic purpura and hemolytic uremic syndrome has been withdrawn.
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CLINICAL_TRIALS safety_alert · 2012-11-20Clinical Trial Update: Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4
An update on a clinical trial indicates an outbreak of hemolytic-uremic syndrome linked to Escherichia coli serotype O104:H4, with the study…
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis [NA]
The trial evaluated repetitive intestinal lavage in patients with EHEC-associated hemorrhagic colitis and is now completed.
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CLINICAL_TRIALS trial_result · 2010-05-19Clinical Trial Update: Rituximab in Patients With Relapsed or Refractory TTP-HUS [Phase 2]
Phase 2 trial evaluating rituximab in patients with relapsed or refractory thrombotic thrombocytopenic purpura and hemolytic uremic syndrome…